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Summary: A brief review of the top reports in 2017 on prediabetes and type 2 diabetes treatments, including new ones and those in the pipeline. [This article first appeared on the LongevityFacts.com website. Author: Brady Hartman.]

A paper published in the Lancet shocked the public last year when they reported that 40% of Americans walking around today would develop type 2 diabetes. While type 2 diabetes is a leading cause of premature death, the World Health Organization (WHO) upset even more people when they announced that prediabetes – the precursor state to diabetes – kills far more people.

Here’s a look back at the reports in 2017 on the ways to prevent type 2 diabetes and prediabetes and the promising treatments in the pipeline for these two forms of diabetes.

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Scientists are searching for an effective Parkinsons treatment.


Summary: A disease-modifying drug for Parkinson’s disease remains the goal of researchers as they develop promising treatments using gene therapy, autophagy upregulators, and brain mapping. [Author: Brady Hartman. This article first appeared on LongevityFacts.]

Parkinson’s, Alzheimer’s and other forms of dementia are diseases of aging, and the incidence of these conditions rise with each passing year. Doctors expect these disorders to ramp up with increasing life expectancies.

Researchers aren’t just focusing on treatments for Alzheimer’s disease. Fortunately, scientists throughout the world are developing promising treatments for Parkinson’s disease as well.

8 top videos of the future of medicine from 2017.


Summary: a review of the eight top videos on the future of medicine reported in 2017. [This article first appeared on the LongevityFacts.com website. Author: Brady Hartman.]

Throughout 2017, a new breed of researchers called geroscientists were working on revolutionary medical advances, including cancer-seeking bacteriobots, lab-grown organs, soft robots that help an ailing heart to beat, weaponized killer T-cells, plans for radical life extension, advancements in CRISPR gene editing, and the emergence of the microbiome in human health.

These videos came from many sources including Kurzsegat, Popular Science, and the journal Nature. Here’s a look back at the 8 videos in 2017 that shows us the coming revolutionary advances in healthcare.

The Philippines’ most active volcano has shown signs of imminent eruption, forcing thousands of people on the main island of Luzon to evacuate.

Authorities upgraded the alert level at the Mayon volcano in the southern part of Luzon to “level 3” Sunday after observing steam eruptions and a bright lava glow.

As many as 3,000 villagers fled their homes while the volcano spewed ash, according to CNN affiliate CNN Philippines.

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A tissue-based soft robot that mimics the biomechanics of a stingray has been developed, which could lead to advances in bio-inspired robotics, regenerative medicine and medical diagnostics.

The simple body design of stingrays, specifically, a flattened body shape and side fins that start at the head and end at the base of their tail, makes them ideal to model bio-electromechanical systems on.

The 10-millimeter long robot is made up of four layers: tissue composed of live heart cells, two distinct types of specialized biomaterials for structural support, and flexible electrodes. Imitating nature, the robotic stingray is even able to “flap” its fins when the electrodes contract the heart cells on the biomaterial scaffold.

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Today, at least 45 start-ups are working on chips that can power tasks like speech and self-driving cars, and at least five of them have raised more than $100 million from investors. Venture capitalists invested more than $1.5 billion in chip start-ups last year, nearly doubling the investments made two years ago, according to the research firm CB Insights.


SAN FRANCISCO — For years, tech industry financiers showed little interest in start-up companies that made computer chips.

How on earth could a start-up compete with a goliath like Intel, which made the chips that ran more than 80 percent of the world’s personal computers? Even in the areas where Intel didn’t dominate, like smartphones and gaming devices, there were companies like Qualcomm and Nvidia that could squash an upstart.

But then came the tech industry’s latest big thing — artificial intelligence. A.I., it turned out, works better with new kinds of computer chips. Suddenly, venture capitalists forgot all those forbidding roadblocks to success for a young chip company.

Dennis Wingo sees metals mining, communication stations and telescopes on the moon. The combination of industries will make moon development viable.

The moon is largely made up of metal oxides that could yield new supplies of platinum — perhaps enough to drive prices for the precious metal down to $300 from $1,400 an ounce today. Processing metals on the moon does not require chemicals. Different levels of heat can be used to make different metals. Cheaper platinum will make fuel cells that are so much more effective than combustion engines.

Skycorp’s mission is to fundamentally transform the spacecraft industry, utilizing orbital assembly process, electric propulsion, and modular construction, to create applications unthinkable before.

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MANILA, Philippines – The Philippines‘ most active volcano rumbled back to life Sunday with lava rising to its crater in a gentle eruption that has prompted authorities to evacuate thousands of villagers.

The Philippine Institute of Volcanology and Seismology warned a “hazardous eruption” of Mount Mayon, located in Albay province in the northeastern Philippines, is possible within weeks or even days.

Story continues below.

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Some blogs and news outlets eschew long titles. Publishers want readers to scan a list of topics that fit on one-line each. But, a better title for this article would be:

“Massive electric consumption by cryptocurrency mining:
An unfortunate environmental nightmare will soon pass!
… Proof-of-Work alternatives are on the horizon”

A considerable amount of electricity is used in the process of mining Bitcoin and other cryptocurrencies. Miners are effectively distributed bookkeepers, and this use of resources is part of a system called “proof-of-work”. It keeps the books fair, honest, and without an ability for the miners to collude (In other words, they cannot ‘cook the books’).

What makes the process unique and exciting is that this “distributed consensus” does not require a trusted authority, like a bank. In fact, the whole point of the blockchain revolution is that users trust a mechanism rather than a bank, government or even each other.

But, for any network that hopes to become part of the financial fabric, it must be ubiquitous and in constant motion. Proof-of-work just doesn’t make the grade, because it doesn’t scale. The need for miners to prove that they did something complex sucks up too much power. If Bitcoin or any proof-of-work currency were to be adopted for even a small fraction of commercial and personal transactions, it would overwhelm the world’s energy services.

One reader suggests the problem will be solved by the recent boom in shale fracking and renewable, non-polluting energy. He points out that crypto mining may even drive a market for distributed, clean electric production.

Unfortunately, clean and cheap power makes the problem worse. Even if electric capacity were to rise dramatically and experience a great cost reduction, cryptocurrency networks would automatically demand all the extra electricity. It is a no-win game, because mining incentives escalate with an increase in supply or drop in cost.

Will large-scale, blockchain-based networks fail, because of enormous electric demand? Fortunately, the future is not so bad, after all. Although networks, like Bitcoin, currently use proof-of-work to ensure honesty and fairness, it is only one of many possible measurement and enforcement mechanisms. Eventually, developers and miners will swap in another proof mechanism to keep the network humming—and without creating an environmental catastrophe.

Will Change in Proof Come in Time?

The political process for changing the fairness mechanism (“forking the code”) is complex and fraught with infighting, but the problem will eventually be addressed, and it will be solved before electricity becomes a critical issue. Despite a messy voting process, the miners have too much at stake to ignore this problem much longer.

Various proof alternatives are already being used in altcoins. Since Bitcoin is perfectly free to steal these techniques (none can be protected by patent or trade secrecy), we can think of these other coins as beta-tests for Bitcoin. How so? As the first and biggest elephant in the room, Bitcoin will likely reign supreme, as long as it doesn’t wait too long before grabbing the best technology and tucking it into its quiver.

Proof-of-Work Alternatives

  • One method, already used by some altcoins, is called “proof-of-stake”. It’s a bit like getting voting rights based on how much land you own. This method does not demand lots of electricity—but some analysts feel that is not as fair, because it cedes network control to the wealthiest members.
  • Another method, called BFT Replication was developed by Marko Vukolić, at the IBM Blockchain Group in Zurich Switzerland. It might be exactly what we need.
  • Yet another method was proposed by C.V. Alkan, an amateur analyst with a passion to solve this problem. He calls it Distributed Objective Consensus.

These aren’t the only alternatives to proof-of-work. Ultimately, one or more of these fairness enforcement mechanisms will make its way into Bitcoin and other currencies and blockchain services. In my opinion, the electrical crisis is a genuine threat, but it is one that with a solution that will be implemented soon—perhaps even this year.

Related:


Philip Raymond co-chairs CRYPSA, publishes A Wild Duck and hosts the New York Bitcoin Event. He is keynote speaker at the Cryptocurrency Expo in India this month. Click Here to inquire about a presentation or consulting engagement.