Cellular senescence used against cancer.
Researchers from the Walter and Eliza Hall Institute, the Monash Institute of Pharmaceutical Sciences, and Cancer Therapeutics CRC have developed a new type of drug that harnesses cellular senescence as a weapon against cancer [1].
Study abstract
Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug-delivery system that allows rapid response to heart attacks without surgical intervention. In laboratory and animal testing, the system proved to be effective at dissolving clots, limiting long-term scarring to heart tissue and preserving more of the heart’s normal function.
“Our approach would allow health-care providers to begin treating heart attacks before a patient reaches a surgical suite, hopefully improving patient outcomes,” says Ashley Brown, corresponding author of a paper on the work and an assistant professor in the Joint Biomedical Engineering Program (BME) at NC State and UNC. “And because we are able to target the blockage, we are able to use powerful drugs that may pose threats to other parts of the body; the targeting reduces the risk of unintended harms.”
Heart attacks, or myocardial infarctions, occur when a thrombus – or clot – blocks a blood vessel in the heart. In order to treat heart attacks, doctors often perform surgery to introduce a catheter to the blood vessel, allowing them to physically break up or remove the thrombus. But not all patients have quick access to surgical care.
City planners and designers can help make spaces safer in many ways. One strategy is known as Crime Prevention Through Environmental Design (CPTED, pronounced “sep-ted”). This approach is based on the idea that specific built and social environmental features can deter criminal behaviour.
Strategies can be as simple as good maintenance, like rapidly removing graffiti, which can deter some offenders.
Another method is to build houses, streets, transport hubs and retail settings in a way that promotes visibility. This can include making windows and entrances of buildings face each other and clever use of lighting. The enhanced visibility this creates is known as “passive surveillance”, which can deter some offenders.
In July 2018, The Engineer examined how modular fabrication techniques are reshaping the construction industry, enabling clean builds that are cost-effective and time efficient. But while off-site assembly brings many advantages, it can also be restrictive. This has prompted a new wave of engineers to bring the latest technology on-site, elevating the pre-fab to the fabulous.
According to Andrew Watts, CEO of engineering technology firm Newtecnic, this trend is part of a new era of digital construction where robots and drones will become commonplace on site. Digitalisation has penetrated virtually every aspect of design and engineering, but in many ways physical construction itself has remained a stubbornly analogue process, centuries of accumulated human expertise resisting the allure of ones and zeroes, and human hands still doing much of the heavy lifting. Newtecnic’s Construction Labs concept is aiming to change that, merging modular building with on-site construction to deliver perfect finishes on major public buildings.
“We’re using Construction Labs to realise complex projects,” Watts told The Engineer. “Its specific use is in the construction of facades and applications and connections for primary structures.”
Scientific progress, and Internet and mobile coverage proliferation in the last 8 years alone might have decreased the numbers dramatically. Still not as much as to liquidate the spiritual beliefs of the vast majority of the world’s population.
Does God exist? If She does, this is how we got our sacred soul. If She does not, we will soon be able to recreate the soul in machines!
This article is part of a series about how OS Fund (OSF) companies are radically redefining our future by rewriting the operating systems of life. Or as we prefer to think about it: Step 1: Put a dent into the universe. And Step 2: Rewrite the universe. You can see the full OSF collection here and read more about Building a Biological Immune System.
In contemplating the future, I love imagining how our daily lives today will be thought of in the future. What appears sci-fi to us today but will be “normal” 50 years from now? What inefficient and boneheaded things do we do today that future generations will look back and laugh at?
Seeing beyond what’s possible is a rare skill. Being able to design and build beyond what’s possible is even more rare. Put together, this is the unique set of skills and abilities that OSF founders all have in common. Most importantly, they’ve chosen to focus their abilities to tackling the biggest problems humanity faces.
Posted in computing, quantum physics
You’re never too old to live young so long as you put forth effort.
This 63-year-old is showing up people half his age.
Credit: Gerry Mansolill
Check out Synthego’s blog post to explore the possibility of CRISPR aided anti-aging solutions. #aging #genomics #GenomeEngineering https://buff.ly/2Ohmj2F
