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Researchers from Scripps Research have discovered how the proteasome, which is made of protein complexes in the cell that breaks down damaged and unwanted proteins, converts energy into motion to unfold target proteins for recycling.

What is the proteasome?

The proteasome is a protein complex whose job is to break down and recycle proteins that have become damaged or are no longer required. It achieves this via a process called proteolysis, a chemical reaction that breaks the peptide bonds, thus allowing the target protein to be destroyed and broken down into its constituent parts, which become ready to be reused to make new proteins. The enzymes that facilitate this recycling process are known as proteases.

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By Luke Miller

A fungus that can “eat” plastic has been discovered in Pakistan. This discovery could tackle the growing plastic problem the planet is currently facing, by cutting the lifespan of plastic from up to 1000 years, to just weeks.

One of the largest environmental problems we are currently facing is plastic. Taken from sas.org pollution facts and figures:

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STOREY COUNTY — The need for more infrastructure and housing is constraining Tesla Motors’ desire to grow its footprint in Northern Nevada, Tesla CEO Elon Musk said Tuesday.

Musk’s comment came during a technology and innovation summit hosted by Gov. Brian Sandoval at Tesla’s Gigafactory 1 located just outside of Sparks.

Musk said he envisions growing the number of employees at the Nevada factory from roughly 7,000 currently to upward of 20,000 in the future, and more than doubling the physical footprint of the 5.8 million-square-foot lithium-ion battery factory.

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A massive, previously unexplored cave discovered by accident in Canada has been named “Sarlacc’s Pit,” after the multi-tentacled alien beast that first made an appearance in Star Wars: Return of the Jedi.

Officials from Canada’s Ministry of Environment and Climate Change first came across the huge cavern in Wells Gray Provincial Park in British Columbia while conducting a caribou count by helicopter in March.

The sinkhole was later discovered to be the entrance to a cave, and is 328 feet long, 196 feet broad and 600 feet deep. Officials believe it may be Canada’s largest cave.

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Tesla launched a new ‘Enhanced Anti-theft’ system as an aftermarket product last month and we now take a first look at one of the very first installations on a Model X.

There have been strings of Tesla thefts earlier this year that prompt the automaker to offer several new security features.

We reported on several Tesla vehicle thefts through relay attacks in Europe earlier this year.

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As local, federal, and international policies targeting the quality of the air we breathe continue to evolve, questions arise of how effective existing policies have been in improving human health. For example, how many lives have been saved by tough air pollution policies? How many illnesses have been caused by lax policies?

US ozone levels map highlighting highest levels

Annual mean levels of fine particulate matter (PM2.5) pollution declined in the United States between 1990 (left) and 2010 (right), leading to thousands of lives saved, according to researcher Jason West.

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The American missile defense system, strategically placed all around the globe, has been the centerpiece of the “defensive” capabilities of Washington for years. The system relies on anti-aircraft missiles, supposed to shoot down incoming hostile projectiles. But the emergence of unconventional weaponry –namely the hypersonic missiles– has raised demand for new, equally unconventional defense systems.

Apart from hitting an incoming projectile with an intercepting one, the anti-missile research and development in the US revolved around two main ideas – using lasers and hitting hostile missiles with a kinetic device. The US military-industrial companies have been recycling the two concepts for years, fielding several prototypes that never entered full-scale production.

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Analyst Salveen Richter and colleagues laid it out:

The potential to deliver “one shot cures” is one of the most attractive aspects of gene therapy, genetically engineered cell therapy, and gene editing. However, such treatments offer a very different outlook with regard to recurring revenue versus chronic therapies… While this proposition carries tremendous value for patients and society, it could represent a challenge for genome medicine developers looking for sustained cash flow.

For a real-world example, they pointed to Gilead Sciences, which markets treatments for hepatitis C that have cure rates exceeding 90 percent. In 2015, the company’s hepatitis C treatment sales peaked at $12.5 billion. But as more people were cured and there were fewer infected individuals to spread the disease, sales began to languish. Goldman Sachs analysts estimate that the treatments will bring in less than $4 billion this year.

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Critics say that geoengineering efforts are Band-Aid solutions that treat the symptoms of climate change instead of the cause: global carbon emissions. Jim Thomas, the co-executive director of an environmental advocacy organization called the ETC Group, told Nature that he fears the Harvard project could push the concept of geoengineering into the mainstream.

But advocates say that anything that could buy some extra time in the face of looming climate catastrophe is worth exploring.

“I’m studying a chemical substance,” Harvard researcher Zhen Dai told Nature. “It’s not like it’s a nuclear bomb.”

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