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As the coming genetic revolution plays out, we’ll still have sex for most of the same reasons we do today. But we’ll increasingly not do it to procreate.


Another rocket booster will be the application of gene editing technologies like CRISPR to edit the genomes of pre-implanted embryos or of the sperm and eggs used to create them. Just this week, Chinese researchers announced they had used CRISPR to edit the CCR5 gene in the pre-implanted embryos of a pair of Chinese twins to make them immune to HIV, the first ever case of gene editing humans and a harbinger of our genetically engineered future. The astounding complexity of the human genome will put limits on our ability to safely make too many simultaneous genetic changes to human embryos, but our ability and willingness to make these types of alterations to our future children will grow over time along with our knowledge and technological ability.

With so much at stake, prospective parents will increasingly have a stark choice when determining how to conceive their children. If they go the traditional route of sex, they will experience both the benign wisdom and unfathomable cruelty of nature. If they use IVF and increasingly informed embryo selection, they will eliminate most single gene mutation diseases and likely increase their children’s chances of living a longer and healthier life with more opportunity than their unenhanced peers. But the optimizing parents could also set up their children for misery if these children don’t particularly enjoy what they have been optimized to become or see themselves as some type of freakish consumer product with emotions.

But although there will be pros and cons on each side, the fight between conception through good old-fashioned sex and conception in the lab will ultimately not be fair. Differences and competition within and between societies will pressure parents and societies to adopt ever more aggressive forms of reproductive technology if they believe doing so will open possibilities and create opportunities for the next generations rather than close them.

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#needles #HIV #shots #sex #corona


Only smart syringes that break after one use should be used for injections by 2020, the World Health Organization has announced.

The smart ones prevent the plunger from being pulled back after an injection, so they cannot be used again. The new needles are more expensive, but the WHO says the switch would be cheaper than treating the diseases.

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Marc Koska visited Roka earlier this month with a camera crew from the BBC. He wanted to visit because this village’s tragedy underscores the importance of a product he has spent the last 30 years advocating for: safe syringes, designed to be used only once.

WASHINGTON: Scientists have found that people who have a variant of a longevity gene have improved brain skills such as thinking, learning and memory. Researchers found that increasing levels of the gene, called KLOTHO, in mice made them smarter, possibly by increasing the strength of connections between nerve cells in the brain.

“This could be a major step toward helping millions around the world who are suffering from Alzheimer’s disease and other dementias,” said Dena Dubal, an assistant professor of neurology, the David A Coulter Endowed Chair in Aging and Neurodegeneration at the University of California San Francisco (UCSF) and the lead author of the study published in Cell Reports. “If we could boost the brain’s ability to function, we may be able to counter dementias,” Dubal said.

People who have one copy of a variant, or form, of the KLOTHO gene, called KL-VS, tend to live longer and have lower chances of suffering a stroke whereas people who have two copies may live shorter lives and have a higher risk of stroke. In the study, researchers found that people who had one copy of the KL-VS variant performed better on a battery of cognitive tests than subjects who did not have it, regardless of age, sex or the presence of the apolipoprotein 4 gene, the main genetic risk factor for Alzheimer’s disease.

“” Mr Nygard, 77, and his companies have been accused in a civil claim brought by 10 women of operating a “sex-trafficking ring” to transport young victims to his mansion in the Bahamas where they endured depraved abuse.

Andrew, 59, visited the mansion with his former wife, Sarah, Duchess of York, in the northern summer of 2000 shortly after Mr Nygard had settled cases of sexual harassment against three women out of court in Canada.””


Prince Andrew, the Duke of York, faces renewed scrutiny over his judgment after a fashion tycoon at whose Caribbean mansion he stayed was accused of luring girls as young as 14 to the property, where they were drugged and raped.

The allegations against Canadian Peter Nygard are strikingly similar to those against the late financier Jeffrey Epstein, a friend of the duke, which led to Prince Andrew stepping back from his royal duties.

They’re here, they have gears, get used to it.


In a special Valentine’s Day New Rule, Bill explores the latest emerging sexual trend: people who don’t need people – and why it’s bad news for humanity.

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Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Institut Curie in Paris have shown that the protein SPEN plays a crucial role in the process of X-chromosome inactivation, whereby female mammalian embryos silence gene expression on one of their two X chromosomes.

In their landmark research published in Nature on 5 February, the scientists reveal how SPEN targets and silences active on the X chromosome, providing important new insights into the molecular basis of X-inactivation.

In mammals, males and females differ genetically in their sex chromosomes—XX in females and XY in males. This leads to a potential imbalance, as more than a thousand genes on the X chromosome would be expressed in a double dose in females compared to males. To avoid this imbalance, which has been shown to lead to early embryonic lethality, female embryos shut down the expression of genes on one of their two X .

Starfleet Begins


Steven L. Kwast is a retired Air Force general and former commander of the Air Education and Training Command at Joint Base San Antonio-Randolph. A graduate of the United States Air Force Academy with a degree in astronautical engineering, he holds a master’s degree in public policy from Harvard’s Kennedy School of Government. He is a past president of the Air Force’s Air University in Montgomery, Alabama, and a former fighter pilot with extensive combat and command experience. He is the author of the study, “Fast Space: Leveraging Ultra Low-Cost Space Access for 21st Century Challenges.”

Beginning in 2010, and coinciding with the opening of Hillsdale College’s Allan P. Kirby, Jr. Center for Constitutional Studies and Citizenship on Capitol Hill, the College has hosted an annual Constitution Day Celebration in Washington, D.C. to commemorate the signing of the U.S. Constitution on September 17, 1787.

The program—which features speeches, debates, and roundtable discussions—explores the continuing relevance of the Founders’ Constitution for American politics today.

Hillsdale College is an independent institution of higher learning founded in 1844 by men and women “grateful to God for the inestimable blessings” resulting from civil and religious liberty and “believing that the diffusion of learning is essential to the perpetuity of these blessings.” It pursues the stated object of the founders: “to furnish all persons who wish, irrespective of nation, color, or sex, a literary, scientific, [and] theological education” outstanding among American colleges “and to combine with this such moral and social instruction as will best develop the minds and improve the hearts of its pupils.” As a nonsectarian Christian institution, Hillsdale College maintains “by precept and example” the immemorial teachings and practices of the Christian faith.