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Sugar-coated nanoparticles show promise against glioblastoma.
Researchers have developed mannose-coated lipid nanoparticles capable of crossing the blood-brain barrier and delivering therapeutic PTEN mRNA directly to glioblastoma cells, one of the deadliest forms of brain cancer.
Glioblastoma cells have an exceptionally high demand for glucose. By coating the nanoparticles with a sugar molecule called mannose, the researchers took advantage of this metabolic feature, allowing the particles to enter the brain more efficiently and accumulate within tumors.
Once inside the cancer cells, the nanoparticles restored production of PTEN, a critical tumor-suppressor protein that is frequently lost or dysfunctional in glioblastoma. In mouse models, this approach significantly slowed tumor growth, increased median survival by approximately 50%, and showed no measurable toxicity in major organs.
Although these findings are still preclinical and have not yet been tested in humans, they represent an exciting advance in overcoming one of neuro-oncology’s greatest challenges: safely delivering targeted therapies across the blood-brain barrier.
PORTLAND, Ore. – Researchers at Oregon State University have potentially found a new way to treat the most aggressive form of brain cancer, glioblastoma, whose two-year survival rate is less than 30%.
High-frequency waves classified as terahertz occupy a relatively underused region of the electromagnetic spectrum between infrared light and microwaves. Researchers have long recognized their unique potential for applications including ultrafast wireless communication, security screening, remote sensing and medical imaging.
As technologies push toward higher operating frequencies and data rates, photonics-based terahertz systems, which use light at high speed to generate and process terahertz signals, have emerged as a promising alternative to conventional electronic technologies because of their superior bandwidth and power efficiency. However, today’s terahertz optoelectronic systems, which are electronic systems that control light, remain bulky, complex and difficult to scale for widespread use. They typically rely on multiple separate components—including lasers, amplifiers, modulators, sources and detectors—that must be individually made, aligned and interconnected, limiting their use outside specialized laboratory settings.
Now, a UCLA–led research team has demonstrated a way to integrate these functions onto a single semiconductor chip compatible with modern photonic technologies. The breakthrough, published in Nature Communications, paves the way for compact, scalable terahertz systems for next-generation communication, imaging and sensing applications.
Whatever that binary does, it does as you, with your source, your SSH keys and your cloud tokens. Cursor keeps re-running it for as long as the project stays open.
No prompt injection, no agent, no model in the loop, and no prior access to the machine: opening the folder is the entire exploit, and the result is arbitrary code execution as the logged-in user.
AI security firm Mindgard reported the flaw to Cursor on December 15, 2025 and published full technical details on Tuesday, seven months later. There is still no patch, and Cursor has published no advisory for the issue.
Zoom is warning of a critical vulnerability in its desktop client and software development kit for Windows that could be exploited by an unauthenticated party to hijack accounts.
Discovered internally, the security issue is tracked as CVE-2026–53412 and received a severity score of 9.8 out of 10.
In an advisory this week, the messaging platform says that the flaw affects Zoom Workplace for Windows before version 7.0.0, the Windows VDI Client before versions 7.0.10, 6.6.15, and 6.5.18, and the Meeting SDK for Windows before version 7.0.0.
1st comment below.
The executive was “going to be killed,” he told the guard, and he needed to warn someone, according to records of the April 15 incident viewed by The Wall Street Journal.
The encounter, which took place five days after an attempted firebombing of OpenAI Chief Executive Officer Sam Altman’s house, ended without violence or an arrest. But for executives at Anthropic—and across the artificial-intelligence industry—the threat was far from over.
In recent months, mounting opposition to AI has given rise to a surge of violent rhetoric, threats against people and property, and a serious attempt at harm. The phenomenon has executives at tech companies large and small reconsidering their personal security arrangements and how they talk about their products to a public that is increasingly wary of the technology and the societal changes it is ushering in.