Today, we are going to be taking a look at GAIM and what it might mean for treating amyloid-based diseases, such as Alzheimer’s, Parkinson’s, and amyloidosis. This approach has the potential to treat multiple age-related diseases at once by targeting a common characteristic that they all share.
Misfolded proteins cause multiple age-related diseases
Proteins are large, complex molecules that regulate almost everything in our bodies, either directly or indirectly. They do the majority of the work in cells and are critical for the function, regulation, and structure of tissues and organs.
The Singularity is Near.
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For fifteen years, I’ve assumed that the Matrix Sequels were irredeemable failures. But looking back on them with fresh eyes reveals a pair of films that are exhilarating, interesting, and sometimes hilarious. In this video I try to make sense of these two movies, and what they have to say about free will and the systems that control society.
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Works Cited:
Scarlet protein has a protective effect against Parkinson’s disease in fruit flies.
Researchers at the Department of Biological Sciences at Lehigh University in Bethlehem, Pennsylvania, discovered that a protein known as Scarlet has protective effects against the fruit fly version of Parkinson’s disease [1].
Abstract
Parkinson’s Disease (PD) is characterized by the loss of dopaminergic neurons, resulting in progressive locomotor dysfunction. Identification of genes required for the maintenance of these neurons should help to identify potential therapeutic targets. However, little is known regarding the factors that render dopaminergic neurons selectively vulnerable to PD. Here we show that Drosophila melanogaster scarlet mutants exhibit an age-dependent progressive loss of dopaminergic neurons, along with subsequent locomotor defects and a shortened lifespan. Knockdown of Scarlet specifically within dopaminergic neurons is sufficient to produce this neurodegeneration, demonstrating a unique role for Scarlet beyond its well-characterized role in eye pigmentation.
DARPA seeks to achieve high levels of brain-system communications without surgery, in its new program, Next-Generation Nonsurgical Neurotechnology (N3).
Cientistas conectaram o cérebro de 3 pessoas, permitindo que elas compartilhassem os pensamentos! smile
Neuroscientists have successfully hooked up a three-way brain connection to allow three people share their thoughts – and in this case, play a Tetris-style game. The team thinks this wild experiment could be scaled up to connect whole networks of people, and yes, it’s as weird as it sounds.
It works through a combination of electroencephalograms (EEGs), for recording the electrical impulses that indicate brain activity, and transcranial magnetic stimulation (TMS), where neurons are stimulated using magnetic fields.
The researchers behind the new system have dubbed it BrainNet, and say it could eventually be used to connect many different minds together, even across the web.
