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Scientists hoping to get a glimpse of molecules that control brain activity have devised a new probe that allows them to image these molecules without using any chemical or radioactive labels.

Currently the gold standard approach to imaging molecules in the brain is to tag them with radioactive probes. However, these probes offer low resolution and they can’t easily be used to watch dynamic events, says Alan Jasanoff, an MIT professor of biological engineering.

Jasanoff and his colleagues have developed new sensors consisting of proteins designed to detect a particular target, which causes them to dilate blood vessels in the immediate area. This produces a change in blood flow that can be imaged with magnetic resonance imaging (MRI) or other imaging techniques.

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Great.


Research published in Acta Neuropathologica, identified alterations in a protein known as ATRX in human brain tumours; researchers might also be able to target microRNAs directly, altering their levels to make cancer cells less likely to form tumours.

A recent study suggests that two recently discovered genetic differences between brain cancer cells and normal tissue cells could offer clues to tumour behaviour and potential new targets for therapy.

Published in Acta Neuropathologica, the study identified alterations in a protein known as ATRX in human brain tumours that arise as part of a genetically inherited condition known as neurofibromatosis type 1 (NF1). The disorder, marked initially by benign tumours on nerves, often leads to brain cancer, and although most NF1-related malignancies are nonaggressive, a fraction are “high-grade” and difficult to treat, experts say.

Hmmmm.


Sam Gussman arrived four years ago at Stanford University hoping to eventually parlay an engineering degree into a product manager job at Google or Facebook.

Working for the National Security Agency or other intelligence bureaus never crossed his mind. For Gussman, the government didn’t seem like the place for the most exciting, cutting-edge research in human computer interaction — his area of interest. Plus, it did no on-campus recruiting, unlike the many tech startups that e-mailed him daily about job opportunities and happy hours.

That career plan changed dramatically after Gussman took a new graduate class at Stanford’s engineering school called Hacking for Defense, or H4D, where he got to tackle real-life national security challenges. There he met with U.S. military officers and studied the mental duress soldiers face during combat and then worked on software that distinguishes insurgents from civilians in video feeds from drones. Suddenly government work was “super cool.”

A huge discovery has just been made about Parkinson’s disease that scientists may have been looking for answers in the wrong place all along. Scientists have found that there is a strong correlation between symptoms of Parkinson’s and bacteria in the gut, not the brain, based on examinations of mice.

Parkinson’s disease is the second most common debilitating brain disorder in the world after Alzheimer’s. It is a neurodegenerative disease that involves a type of protein that builds up around brain cells and then causes the patient to lose motor function. Naturally, scientists had been looking at the brain for answers in dealing with it, but a new study finds that perhaps the answer was in the gut bacteria all along, according to an Axial Biotherapeutics statement.

The finding could lead to a new generation of probiotics that are far more sophisticated than typical brands currently available to the public.

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Correction:
Fluid intelligence is just the ability to think and reason abstractly. The higher your fluid intelligence, in theory, the faster and more efficient you become at thinking abstractly.

One study shows that people with very high fluid intelligence have closer connections between neurons which allows them to reach conclusions faster. Another shows that the brain organizes itself in a more efficient manner allowing them to use less brain power to reach the same conclusions someone of lower intelligence would take longer to come to.

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Radiologists have finally figured out why astronauts who spend a lot of time in space get impaired vision.

The problem, called visual impairment intracranial pressure (VIIP) syndrome, has been reported in two-thirds of astronauts who go up to the International Space Station.

And according to a new study from researchers at the University of Miami — reported Monday at the Radiological Society of North America’s annual conference — those changes to the eye have everything to do with changes in the fluid that surrounds the brain and spinal cord.

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In an epidsode of the dystopian near-future series, Black Mirror, a small, implantable device behind the ear grants the ability to remember, access, and replay every moment of your life in perfect detail, like a movie right before your eyes.

Theodore Berger, a biomedical engineer at the University of Southern California, can’t promise that level of perfect recall—perhaps for the better—but he is working on a memory prosthesis. The device, surgically implanted directly into the brain, mimics the function of a structure called the hippocampus by electrically stimulating the brain in a particular way to form memories—at least in rats and monkeys. And now, he’s testing one that could work in humans.

Berger’s device hinges on a theory about how the hippocampus transforms short-term memories, like where you deposited your keys, into long-term memories—so you can find them later. In his early experiments, he played a tone and then puffed air in a rabbit’s face, causing it to blink. Eventually, just playing the tone would make the rabbit blink, just like Pavlov’s famous salivating dogs. Berger recorded the hippocampus’ activity with electrodes, and as the rabbits learned to associate the tone with the air puff, patterns in those signals changed in a predictable way.

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