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Early Life Experiences Biologically and Functionally Mature the Brain

Experiences early in life have an impact on the brain’s biological and functional development, shows a new study by a team of neuroscientists. Its findings, which centered on changes in mice and rats, reveal how learning and memory abilities may vary, depending on the nature of individual experiences in early life.

“The implications of this are many, including environmental influences on mental health, the role of education, the significance of poverty, and the impact of social settings,” says Cristina Alberini, a professor in New York University’s Center for Neural Science and the senior author of the paper, which appears in the journal Nature Communications.

“These results also offer promise for potential therapeutic interventions,” add Alberini and Benjamin Bessières, an NYU postdoctoral researcher and the paper’s co-lead author. “By identifying critical time periods for brain development, they provide an indicator of when pharmaceutical, behavioral or other type of interventions may be most beneficial.”

The scent of a rose improves learning during sleep

Fragrance helps learning even during sleep!


Effortless learning during sleep is the dream of many people. The supportive effect of smells on learning success when presented both during learning and sleep was first proven in an extensive sleep laboratory study. Researchers at the University of Freiburg—Medical Center, the Freiburg Institute for Frontier Areas of Psychology and Mental Health (IGPP) and the Faculty of Biology at the University of Freiburg have now shown that this effect can be also achieved very easily outside the lab. For the study, pupils in two school classes learned English vocabulary—with and without scent sticks during the learning period and also at night. The students remembered the vocabulary much better with a scent. The study was published in the Nature Group’s Open Access journal Scientific Reports on 27 January 2020.

“We showed that the supportive effect of fragrances works very reliably in and can be used in a targeted way,” said study leader PD Dr. Jürgen Kornmeier, head of the Perception and Cognition Research Group at the Freiburg-based IGPP and scientist at the Department of Psychiatry and Psychotherapy at the University of Freiburg—Medical Center in Germany.

The smell of roses when learning and sleeping

For the study, first author and student teacher Franziska Neumann conducted several experiments with 54 students from two 6th grade classes of a school in southern Germany. The young participants from the group were asked to place rose-scented incense sticks on their desks at home while learning English and on the bedside table next to the bed at night. In another experiment, they also placed the incense sticks on the table next to them during a vocabulary test at school during an English test. The results were compared with test results in which no incense sticks were used during one or more phases.

Mongoose’s Immunity to Cobra Venom Explained

Why could the mongoose Rikki Tikki Tavi attack deadly snakes with impunity in Kipling’s “Jungle Book?” Because he has a uniquely mutated receptor for a brain neurotransmitter called acetylcholine, researchers at the Weizmann Institute of Science report in the Proceedings of the National Academy of Sciences.

The toxins in many snake venoms, including that of cobras, bind to the acetylcholine receptors of their victims, blocking nerve-muscle communications. Molecular biologist Sara Fuchs and her colleagues found that the acetylcholine receptor in mongooses—like that in the snakes themselves—is slightly mutated so that the venom simply bounces off the muscle cells, causing them no harm.

How one entrepreneur is tackling humanity’s most pressing problems

Braintree founder Bryan Johnson, MBA’07, invests in bold ventures on the next frontier.

Bryan Johnson is determined to explore the depths of your mind and help save humanity from its direst threats.

“The biggest revolutions that have happened over the past couple of decades have largely been done on silicon—the transistors we build, the computers we have, the internet, our smartphones,” said Johnson, MBA’07. “The next great revolutions will be evolving our cognition and predictably engineering atoms, molecules, organisms and complex systems.”