IBM Research hosts a fascinating seminar with Rafael Yuste, a world leader in optical methods for brain research. According to Professor Yuste, lifting neuroscience studies from looking at neurons one at a time to ensembles or functional units is key in our quest to understanding how brains work.

Rafael Yuste is a Professor of Biological Sciences and Neuroscience at Columbia University and Co-director of the Kavli Foundations Institute for Neural Circuitry. He recently helped launch the BRAIN Initiative, a large-scale scientific project to systematically record and manipulate the activity of complete neural circuits.

In this seminar, Rafael Yuste shows the results from his group’s two-photon holographic methods to selectively image and manipulate the activity of neuronal populations in 3D in vivo. These experiments – from imaging neuron activities, triggering of neuron ensemble activities, and even altering behavioral choices bi-directionally – are shedding light on the possibility of neuronal ensembles being functional building blocks of cortical circuits.

We’re going to be a little different. Our route into special relativity might be thought of as top-down, taking the idea of a unified space-time seriously from the get-go and seeing what that implies. We’ll have to stretch our brains a bit, but the result will be a much deeper understanding of the relativistic perspective on our universe.

The development of relativity is usually attributed to Albert Einstein, but he provided the capstone for a theoretical edifice that had been under construction since James Clerk Maxwell unified electricity and magnetism into a single theory of electromagnetism in the 1860s. Maxwell’s theory explained what light is — an oscillating wave in electromagnetic fields — and seemed to attach a special significance to the speed at which light travels. The idea of a field existing all by itself wasn’t completely intuitive to scientists at the time, and it was natural to wonder what was actually “waving” in a light wave.