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6 Ways to Regulate Your Nervous System (According to Neuroscience)

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UT researchers successfully test ‘brain-powered’ wheelchair for disabled individuals

According to an article by the university, the study is significant because it is a sign of future viability for noninvasive technology to help those with limited motor function.

“We demonstrated that the people who will actually be the end users of these types of devices are able to navigate in a natural environment with the assistance of a brain-machine interface,” said José del R. Millán, professor at the Cockrell School of Engineering’s Chandra Family Department of Electrical and Computer Engineering and leader of the international research team.

Vaccine for lethal brain cancer extends the lifespan of patients

People affected by the lethal glioblastoma cancer only live for 12–18 months after diagnosis.

A global trial that began in 2007 has confirmed that a vaccine for the treatment of the most lethal brain cancer can give patients years of extended life.

Glioblastoma is not only the most common form of brain cancer but is also one of the deadliest. People affected by the disease only live just 12–18 months after the diagnosis, or even less.

Now, thanks to the vaccine DCVax, some 2,500 people who are diagnosed with deadly cancer in the UK could be benefitted.

Dr. Peggy Hamburg, MD — Chair, Nuclear Threat Initiative (NTI), bio Advisory Group

Guarding Against Future Global Biological Risks — Dr. Margaret “Peggy” Hamburg, MD — Chair Nuclear Threat Initiative, bio Advisory Group; Commissioner, Bipartisan Commission on Biodefense; former Commissioner, U.S. Food and Drug Administration (FDA)


Dr. Margaret “Peggy” Hamburg, MD is an internationally recognized leader in public health and medicine, who currently serves as chair of the Nuclear Threat Initiative’s (NTI) bio Advisory Group (https://www.nti.org/about/people/margaret-hamburg-md/), where she has also served as founding vice president and senior scientist. She also currently holds a role as Commissioner on the Bipartisan Commission on Biodefense (https://biodefensecommission.org/teams/margaret-a-hamburg/).

Dr. Hamburg previously served as foreign secretary of the National Academy of Medicine and is a former Commissioner of the U.S. Food and Drug Administration (FDA), having served for almost six years where she was well known for advancing regulatory science, modernizing regulatory pathways, and globalizing the agency. Previous government positions include Assistant Secretary for Planning and Evaluation, U.S. Department of Health and Human Services, Health Commissioner for New York City, and Assistant Director of the National Institute of Allergy and Infectious Diseases, National Institutes of Health.

In her role, as Foreign Secretary of the National Academy of Medicine, the health arm of the National Academy of Sciences, Engineering and Medicine, Dr. Hamburg served as senior advisor on international matters and was the liaison with other Academies of Medicine around the world. She is an elected member of the Council on Foreign Relations and the National Academy of Medicine.

Dr. Hamburg currently sits on the boards of the Commonwealth Fund, the Simons Foundation, the Urban Institute, the Global Alliance for Vaccines and Immunization, the Parker Institute for Cancer Immunotherapy and the American Museum of Natural History. She is chair of the Joint Coordinating Group for the Coalition for Epidemic Preparedness and Innovation, and a member of the Harvard University Global Advisory Council, the Global Health Scientific Advisory Committee for the Gates Foundation, the Harvard Medical School Board of Fellows, and the World Dementia Council.

This Week in The Journal

Kazuaki Ikeda, Masaki Kataoka, and Nobuaki K. Tanaka.

(see pages 8621–8628)

Current flowing through the plasma membrane of individual neurons causes fluctuations in the surrounding electrical field that can be detected with extracellular electrodes. Changes in the local field potential can influence the activity of all neurons within that field. For example, when two unmyelinated axons are closely apposed, an action potential in one axon alters the membrane potential of the other. This phenomenon is called ephaptic signaling. Ephaptic signaling is most prominent in layered neural structures in which numerous similarly oriented neurons are synchronously active. In fact, ephaptic signaling is thought to promote synchronous firing of cerebellar Purkinje cells and cortical and hippocampal pyramidal neurons. Ikeda et al. now show that ephaptic signaling originating in Drosophila eyes can influence activity in olfactory sensory neurons (OSNs) in the antennae.

‘I’m just carrying on’: vaccine gives brain cancer patient years of extra life

It’s been seven years since Nigel French was woken up in the middle of the night by his wife after having a seizure, which came out of the blue after experiencing a mild headache – something he had simply put down to blocked sinuses.

“She told me that the ambulance had arrived and I was like: ‘what ambulance?’” recalls French, 53, a mechanic who was diagnosed with glioblastoma that required urgent surgery, without which he would have had only months to live.

In a different scenario, the impact of one of the most aggressive forms of brain cancer would have taken its toll by now, but thanks to a revolutionary vaccine, he is not only still alive but continuing to work and enjoy all that life has to offer.

Empathy Estimated Using Single-Cell Recordings in Human Brain

Can we measure empathy?

𝐄𝐦𝐩𝐚𝐭𝐡𝐲 𝐄𝐬𝐭𝐢𝐦𝐚𝐭𝐞𝐝 𝐔𝐬𝐢𝐧𝐠 𝐒𝐢𝐧𝐠𝐥𝐞-𝐂𝐞𝐥𝐥 𝐑𝐞𝐜𝐨𝐫𝐝𝐢𝐧𝐠𝐬 𝐢𝐧 𝐇𝐮𝐦𝐚𝐧 𝐁𝐫𝐚𝐢𝐧

𝘼 𝙨𝙩𝙪𝙙𝙮 𝙞𝙣 𝙚𝙇𝙞𝙛𝙚 𝙖𝙣𝙖𝙡𝙮𝙯𝙚𝙙 𝙩𝙝𝙚 𝙘𝙤𝙣𝙩𝙧𝙞𝙗𝙪𝙩𝙞𝙤𝙣 𝙤𝙛 𝙩𝙝𝙚 𝙞𝙣𝙨𝙪𝙡𝙖 𝙞𝙣 𝙤𝙪𝙧 𝙖𝙗𝙞𝙡𝙞𝙩𝙮 𝙩𝙤 𝙪𝙣𝙙𝙚𝙧𝙨𝙩𝙖𝙣𝙙 𝙩𝙝𝙚 𝙥𝙖𝙞𝙣 𝙤𝙛 𝙤𝙩𝙝𝙚𝙧𝙨 𝙗𝙮 𝙧𝙚𝙘𝙤𝙧𝙙𝙞𝙣𝙜 𝙛𝙧𝙤𝙢 𝙚𝙡𝙚𝙘𝙩𝙧𝙤𝙙𝙚𝙨 𝙚𝙢𝙗𝙚𝙙𝙙𝙚𝙙 𝙞𝙣 𝙩𝙝𝙚 𝙝𝙪𝙢𝙖𝙣 𝙗𝙧𝙖𝙞𝙣 𝙩𝙝𝙖𝙩 𝙢𝙚𝙖𝙨𝙪𝙧𝙚𝙙 𝙣𝙚𝙪𝙧𝙤𝙣𝙖𝙡 𝙖𝙘𝙩𝙞𝙫𝙞𝙩𝙮 𝙞𝙣 𝙞𝙣𝙙𝙞𝙫𝙞𝙙𝙪𝙖𝙡 𝙘𝙚𝙡𝙡𝙨 𝙞𝙣 𝙚𝙥𝙞𝙡𝙚𝙥𝙨𝙮 𝙥𝙖𝙩𝙞𝙚𝙣𝙩𝙨 𝙖𝙨 𝙩𝙝𝙚𝙮 𝙫𝙞𝙚𝙬𝙚𝙙 𝙨𝙝𝙤𝙧𝙩 𝙢𝙤𝙫𝙞𝙚𝙨 𝙤𝙛 𝙖𝙣 𝙖𝙘𝙩𝙧𝙚𝙨𝙨 𝙞𝙣 𝙥𝙖𝙞𝙣. 𝙏𝙝𝙚 𝙨𝙩𝙪𝙙𝙮 𝙞𝙢𝙥𝙧𝙤𝙫𝙚𝙨 𝙤𝙪𝙧 𝙪𝙣𝙙𝙚𝙧𝙨𝙩𝙖𝙣𝙙𝙞𝙣𝙜 𝙤𝙛 𝙩𝙝𝙚 𝙞𝙣𝙝𝙚𝙧𝙚𝙣𝙩 𝙙𝙞𝙛𝙛𝙚𝙧𝙚𝙣𝙘𝙚𝙨 𝙞𝙣 𝙥𝙚𝙤𝙥𝙡𝙚’𝙨 𝙖𝙗𝙞𝙡𝙞𝙩𝙮 𝙩𝙤 𝙚𝙢𝙥𝙖𝙩𝙝𝙞𝙯𝙚 𝙖𝙣𝙙 𝙧𝙚𝙖𝙘𝙩 𝙩𝙤 𝙩𝙝𝙚 𝙥𝙖𝙞𝙣 𝙤𝙛 𝙤𝙩𝙝𝙚𝙧𝙨, 𝙖𝙨 𝙬𝙚𝙡𝙡 𝙖𝙨 𝙥𝙤𝙩𝙚𝙣𝙩𝙞𝙖𝙡 𝙢𝙚𝙘𝙝𝙖𝙣𝙞𝙨𝙢𝙨 𝙛𝙤𝙧 𝙩𝙝𝙚 𝙡𝙖𝙘𝙠 𝙤𝙛 𝙚𝙢𝙥𝙖𝙩𝙝𝙮 𝙞𝙣 𝙘𝙚𝙧𝙩𝙖𝙞𝙣 𝙣𝙚𝙪𝙧𝙤𝙥𝙨𝙮𝙘𝙝𝙞𝙖𝙩𝙧𝙞𝙘 𝙘𝙤𝙣𝙙𝙞𝙩𝙞𝙤𝙣𝙨.


Using intracranial electroencephalographic (iEEG) recordings and single-cell recordings from the human insulae in patients with epilepsy who have electrodes embedded in their brains, scientists have analyzed the contribution of the insula in our ability to understand the pain of others. The study improves our understanding of the inherent differences in people’s ability to empathize and react to the pain of others, as well as potential mechanisms for the lack of empathy in certain neuropsychiatric conditions.

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