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Category: neuroscience – Page 508

EEG hyperscanning during multiuser gaming offers opportunities to study brain characteristics of social interaction under various paradigms. In this study, we aimed to characterize neural signatures and phase-based functional connectivity patterns of gaming strategies during collaborative and competitive alpha neurofeedback games. Twenty pairs of participants with no close relationship took part in three sessions of collaborative or competitive multiuser neurofeedback (NF), with identical graphical user interface, using Relative Alpha (RA) power as a control signal. Collaborating dyads had to keep their RA within 5% of each other for the team to be awarded a point, while members of competitive dyads scored points if their RA was 10% above their opponent’s. Interbrain synchrony existed only during gaming but not during baseline in either collaborative or competitive gaming. Spectral analysis and interbrain connectivity showed that in collaborative gaming, players with higher resting state alpha content were more active in regulating their RA to match those of their partner. Moreover, interconnectivity was the strongest between homologous brain structures of the dyad in theta and alpha bands, indicating a similar degree of planning and social exchange. Competitive gaming emphasized the difference between participants who were able to relax and, in this way, maintain RA, and those who had an unsuccessful approach. Analysis of interbrain connections shows engagement of frontal areas in losers, but not in winners, indicating the formers’ attempt to mentalise and apply strategies that might be suitable for conventional gaming, but inappropriate for the alpha neurofeedback-based game. We show that in gaming based on multiplayer non-verbalized NF, the winning strategy is dependent on the rules of the game and on the behavior of the opponent. Mental strategies that characterize successful gaming in the physical world might not be adequate for NF-based gaming.

Humans are social creatures whose behavior and consciousness are heavily shaped by their environment. Hence, it is natural that hyperscanning, a technique which involves simultaneous recording of physiological activity from more than one subject, is used to deepen our understanding of human interaction. In recent years, hyperscanning has been applied to brain activity to shed light on the neurophysiological representation of various types of interpersonal communication. These range from verbal interaction (Pérez et al., 2017; Ahn et al., 2018), leader-imitator (Dumas et al., 2010; Yun et al., 2012), joint attention and joint decision-making (Toppi et al., 2016; Hu et al., 2018), to teaching or playing music in a duet (Sänger et al., 2012; Müller et al., 2013). Moreover, the neurological coupling of mothers and their infants was investigated for positive and negative emotions and their regulation (Reindl et al., 2018; Santamaria et al., 2020).

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I wanted to focus on the animal testing portion of the Show and Tell. Neuralink representatives showed us videos of a pig that has a cortex and spinal chip in its body. It also has pin points on joints in its leg that are sending data to the Neuralink scientist. When the scientist stimulates a joint it creates an uncontrolled movement. The pig moves its leg without wanting too, but because someone else wanted it too, the pig did not want to move. That’s the focus of this video.

#neuralink #neuroscience #videoessay #yuvalnoahharari #elonmusk #podcast #neurology

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Jeff Lichtman is Jeremy R. Knowles Professor of Molecular and Cellular Biology at Harvard. He received an A.B. from Bowdoin (1973), and an M.D. and Ph.D. from Washington University in St. Louis (1980) where he worked for 30 years before moving to Cambridge (2004). He is a member of Harvard’s newly established Center for Brain Science. Jeff’s research interests revolve around the question of how mammalian brain circuits are physically altered by experiences, especially in early life. He has focused on the dramatic re-wiring of neural connections in early postnatal development. More recently his research has focused on developing new electron microscopy methods to map the entire wiring diagram of the developing and adult brain. One of the principal aims of this “connectomics” approach is to uncover the ways information is stored in neural networks.

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

On January 18, 2013, Caltech hosted TEDxCaltech: The Brain, a forward-looking celebration of humankind’s quest to understand the brain, by exploring the past, present and future of neuroscience. Visit TEDxCaltech.com for more details.

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https://www.youtube.com/watch?v=i2W570VgV6I

David C. Van Essen is the Alumni Endowed Professor in the Anatomy & Neurobiology Department at Washington University in St. Louis. He has pioneered the use of surface-based analysis methods to characterize the structure, function, development, and connectivity of the cerebral cortex. He is Principal Investigator for the NIH Human Connectome Project, a large-scale effort to map brain circuitry and its relationship to behavior in healthy adults. His physiological and anatomical studies have provided deep insights into cortical functional organization. He has served as Editor-in-Chief of the Journal of Neuroscience, President of the Society for Neuroscience, and Head of the Anatomy & Neurobiology Department for 20 years. He is a fellow of the AAAS and received the Raven Lifetime Achievement Award from the St. Louis Academy of Sciences and the Krieg Cortical Discoverer Award from the Cajal Club.

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

On January 18, 2013, Caltech hosted TEDxCaltech: The Brain, a forward-looking celebration of humankind’s quest to understand the brain, by exploring the past, present and future of neuroscience. Visit TEDxCaltech.com for more details.

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Scientists have labored for decades to understand how brain structure and functional connectivity drive intelligence. A new analysis offers the clearest picture yet of how various brain regions and neural networks contribute to a person’s problem-solving ability in a variety of contexts, a trait known as general intelligence, researchers report.

They detail their findings in the journal Human Brain Mapping.

The study used “connectome-based predictive modeling” to compare five theories about how the gives rise to , said Aron Barbey, a professor of psychology, bioengineering and neuroscience at the University of Illinois Urbana-Champaign who led the new work with first author Evan Anderson, now a researcher for Ball Aerospace and Technologies Corp. working at the Air Force Research Laboratory.

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Transplanting a patient’s own hematopoietic stem cells may defer the progression of disability longer in patients with secondary progressive multiple sclerosis (SPMS) than treatment with other anti-inflammatory disease-modifying therapies (DMT), reports a study published in the journal Neurology “Hematopoietic Stem Cell Transplantation in People With Active Secondary Progressive Multiple Sclerosis”.

“Hematopoietic stem cell transplants have been previously found to delay disability in people with relapsing-remitting MS, but less is known about whether such transplants could help delay disability during the more advanced stage of the disease,” said Matilde Inglese, MD, PhD, professor of neurology at the University of Genoa in Italy and senior author of the study. “Our results are encouraging because while current treatments for SPMS have modest or small benefits, our study found stem cell transplants may not only delay disability longer than many other MS medications, they may also provide a slight improvement in symptoms.”

Patients initially diagnosed with relapsing-remitting MS, where periods of active flare-up of symptoms alternate spans of remission, eventually develop SPMS where the disease worsens gradually but steadily. The exact mechanisms leading to increased neurodegeneration in SPMS are unclear, but evidence suggests a major role of innate and adaptive immune mechanisms that drive inflammation in the brain parenchyma, the leptomeninges, and the cerebrospinal fluid.

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You may have heard the phrase, “You are what you eat.” It’s no surprise that what you put into your body directly impacts how you feel and other aspects of your health, including cognitive function.

In fact, diets that contain certain amounts of minerals like sodium and potassium could have an effect on brain function, especially in older adults, according to a recent study published in Global Transitions.

Researchers from China found diets higher in sodium were associated with a higher risk of cognitive decline and poor and deteriorated memory. On the other hand, participants in the study who had more potassium intake in their diet were associated with higher cognitive function.

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