Lifeboat Foundation

And going forward, we’ll do this with far more knowledge of what we’re doing, and more control over the genes of our progeny. We can already screen ourselves and embryos for genetic diseases. We could potentially choose embryos for desirable genes, as we do with crops. Direct editing of the DNA of a human embryo has been proven to be possible — but seems morally abhorrent, effectively turning children into subjects of medical experimentation. And yet, if such technologies were proven safe, I could imagine a future where you’d be a bad parent not to give your children the best genes possible.

Computers also provide an entirely new selective pressure. As more and more matches are made on smartphones, we are delegating decisions about what the next generation looks like to computer algorithms, who recommend our potential matches. Digital code now helps choose what genetic code passed on to future generations, just like it shapes what you stream or buy online. This might sound like dark science fiction, but it’s already happening. Our genes are being curated by computer, just like our playlists. It’s hard to know where this leads, but I wonder if it’s entirely wise to turn over the future of our species to iPhones, the internet and the companies behind them.

Discussions of human evolution are usually backward looking, as if the greatest triumphs and challenges were in the distant past. But as technology and culture enter a period of accelerating change, our genes will too. Arguably, the most interesting parts of evolution aren’t life’s origins, dinosaurs, or Neanderthals, but what’s happening right now, our present – and our future.

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In a new article published in eNeuro, fifteen leading scientists of the European Human Brain Project (HBP) outline how a new culture of collaboration and an era of digitalization has transformed neuroscience research over the last decade.

“The way we study the brain has changed fundamentally in recent years,” says first author Katrin Amunts, HBP Scientific Director, Director of the C. and O. Vogt-Institute of Brain Research, Düsseldorf and Director at the Institute of Neuroscience and Medicine at Research Centre Jülich. “In the past, separate communities have often focused on specific aspects of neuroscience, and the problem was always how to link the different worlds, for example, in order to explain a certain cognitive function in terms of the underlying neurobiology.”

Continue reading “The beginning of a new paradigm for understanding the brain” »

Brain research has in recent years indisputably entered a new epoch, driven by substantial methodological advances and digitally enabled data integration and modeling at multiple scales – from molecules to the whole system. Major advances are emerging at the intersection of neuroscience with technology and computing. This new science of the brain integrates high-quality basic research, systematic data integration across multiple scales, a new culture of large-scale collaboration and translation into applications. A systematic approach, as pioneered in Europe’s Human Brain Project (HBP), will be essential in meeting the pressing medical and technological challenges of the coming decade.

Summary: Floods of calcium that originate from hippocampal neurons can also boost learning, a new study reports.

Source: Columbia University.

Scientists have long known that learning requires the flow of calcium into and out of brain cells. But researchers at Columbia’s Zuckerman Institute have now discovered that floods of calcium originating from within neurons can also boost learning. The finding emerged from studies of how mice remember new places they explore.

An is an external information processing system that augments the brain’s biological high-level cognitive processes.

An individual’s would be comprised of external memory modules 0, processors 0, IO devices and software systems that would interact with, and augment, a person’s biological brain. Typically this interaction is described as being conducted through a direct brain-computer interface 0, making these extensions functionally part of the individual’s mind.

Individuals with significant exocortices can be classified as transhuman beings.

Summary: Neurons in the anterior cingulate store social rank information to inform upcoming decisions. The findings could shed new light on social deficits associated with ASD and schizophrenia.

Source: Mass General.

New research in mice has identified neurons in the brain that influence competitive interactions between individuals and that play a critical role in shaping the social behavior of groups.

US-based Kernel released a piece of wearable helmet tech called the Kernel Flow that uses near-infrared light to scan your brain with lasers.

Her fur clothes were mixed with moose brains.

A full-body reconstruction of a Neolithic woman who lived 4,000 years ago is now on display at a museum in Sweden.

Summary: Researchers have identified a neural circuit that helps suppress the execution of planned actions in response to specific cues.

Source: Max Planck Florida.

Planned movement is essential to our daily lives, and it often requires delayed execution. As children, we stood crouched and ready but waited for the shout of “GO!” before sprinting from the starting line. As adults, we wait until the traffic light turns green before making a turn. In both situations, the brain has planned our precise movements but suppresses their execution until a specific cue (e.g., the shout of “GO!” or the green light).