Glioblastoma tumors take advantage of mechanisms used to create neurons to spread far and wide, scientists in Germany say.
Category: neuroscience – Page 487
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Scientists from the University of Birmingham have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma.
The research, published today in Clinical and Translational Medicine, used cell and animal models to demonstrate that when taken orally the candidate drug, known as AZD1390, can block the response to DNA damage in nerve cells and promote regeneration of damaged nerves, so restoring sensory and motor function after spinal injury.
The announcement comes weeks after the same research team showed a https://medicalxpress.com/news/2022-05-spinal-cord-injury-treatment.html">different investigational drug (AZD1236) can reduce damage after spinal cord injury, by blocking the inflammatory response. Both studies were supported by AstraZenecaâs Open Innovations Program, which shares compounds, tools, technologies and expertise with the scientific community to advance drug discovery and developmentâŠ
To build a true artificial mind, first map out how thinking works. Enter the Common Model of Cognition.
How the virus behind covid-19 enters the brain was somewhat of a mystery, but new evidence hints it may build tiny tubes from nose cells to brain cells that it can shuttle through.
People who have at least two of the conditions type 2 diabetes, heart disease, or stroke are twice as likely to develop dementia. Research from Swedenâs Karolinska Institutet that was published in the journal Alzheimerâs.
Alzheimerâs disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common form of dementia and accounts for 60 to 80 percent of dementia cases. There is no current cure for Alzheimerâs disease, but there are medications that can help ease the symptoms.
University of Iowa researchers have confirmed in a new study that a specific region in the brain is critical to governing the mindâs communication with the bodyâs motor control system. The findings could yield advances in treatment for Parkinsonâs disease, as declining motor coordination is a central symptom of the disorder.
In experiments with humans, the researchers pinpointed the subthalamic nucleus as the region in the brain that communicates with the motor system to help the body stop an action. This communication is vital because it helps humans avoid surprises and react to potentially dangerous or unforeseen circumstances.
The subthalamic nucleus is a tiny grouping of cells that is part of the basal ganglia, which is a key circuit in controlling movement. The basal ganglia takes initial motor commands generated in the brain and either amplify or halt specific parts of those commands as they pass from the central nervous system to the spinal cord.
Figuring out whatâs going on in the brain is generally considered to be somewhere between extremely difficult and impossible. One major challenge is that the best ways to do so are room-sized machines relegated to hospitals â but brain.space is hoping that its portable, powerful and, most importantly, user-friendly EEG helmet could power new applications and treatments at home and, as a sort of cork pop for its debut, in space.
Electroencephalography, or EEG, is an established method for monitoring certain signals the brain produces. An EEG can indicate which areas of the cortex are active, whether the user is concentrating, agitated, and so on. Itâs not nearly as precise as an MRI, but all you need for an EEG is a set of electrical contacts on the scalp, while an MRI machine is huge, loud and incredibly expensive.
Thereâs been precious little advancement in EEG tech, though, and itâs often done more or less the same way it was done decades ago. Recently, thatâs begun to change with devices like Cognixionâs, which uses re-engineered EEG to interpret specific signals with the goal of allowing people with motor impairments to communicate.
Credit: Neuroimaging and Informatics Institute:
Dopaminergic Transmission.
Handbook of Basal Ganglia Structure and Function, Second Edition: https://www.sciencedirect.com/topics/neuroscience/dopaminergic-transmission.
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Antoine Galand, Director of Technology, GraphWear
Nanotechnology was once the stuff of science fiction, but today the concept of creating devices and machines that are several thousand times smaller than the width of a human hair is a well-established fact. The rise of nanotechnology has already transformed industries ranging from consumer electronics to textile manufacturing and cosmetics by unlocking new materials and processes at the nanoscale. The device youâre reading this on, for example, is only possible because of techniques adopted in the semiconductor industry that enable us to pattern silicon and metals to create the microscopic circuits and switches that are at the heart of modern computers.
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