Lifeboat Foundation

Tomatoes gene-edited to produce vitamin D, the sunshine vitamin, could be a simple and sustainable innovation to address a global health problem.

Researchers used gene editing to turn off a specific molecule in the plant’s genome which increased provitamin D3 in both the fruit and leaves of tomato plants. It was then converted to vitamin D3 through exposure to UVB light.

Vitamin D is created in our bodies after skin’s exposure to UVB light, but the major source is food. This new biofortified crop could help millions of people with vitamin D insufficiency, a growing issue linked to higher risk of cancer, dementia, and many leading causes of mortality. Studies have also shown that vitamin D insufficiency is linked to increased severity of infection by Covid-19.

Many criticisms have been leveled against Elon Musk—that he’s part of the elite, that Tesla has been the beneficiary of government handouts and exemptions, that his transhumanist Neuralink is a brain-data-mining operation. Yet his planned purchase of Twitter, his supposed free-speech absolutism, and his subsequent renunciation of the Democratic Party as “the party of hate” have put Musk squarely in the crosshairs of the woke cartel.

Vitriolic Twitter storms, a New York Times-Financial Times biographical exposé, a slew of hit pieces and scaremongering segments in the legacy media, and allegations of sexual harassment have dogged the automobile magnate ever since his Twitter bid. In response, Musk announced on Twitter that he’s assembling a legal crew to sue defamers and defend Tesla (and likely himself) against lawsuits.

But the best indication that the woke cartel has really gone berserk is its removal of Tesla from the S&P 500’s ESG (Environmental, Social, and Governance) Index. This last rebuff proves that “ESG is a scam.”

This just came out, a day or so ago.

Can the aging process be reversed — or even halted, altogether? If we manage to decode this final mystery of our human biology, we might soon be able to eradicate age-related illnesses like cancer, dementia and heart problems.

Continue reading “More life — Decoding the secret of aging | DW Documentary” »

Just as it’s hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell’s environment. To solve that problem, researchers at Princeton Engineering have developed a method to elucidate a cell’s surroundings so that biologists can make more meaning of gene expression information.

The researchers, led by Professor of Computer Science Ben Raphael, hope the new system will open the door to identifying rare cell types and choosing cancer treatment options with new precision. Raphael is the senior author of a paper describing the method published May 16 in Nature Methods.

The basic technique of linking gene expression with a cell’s environment, called spatial transcriptomics (ST), has been around for several years. Scientists break down tissue samples onto a microscale grid and link each spot on the grid with information about gene expression. The problem is that current computational tools can only analyze spatial patterns of gene expression in two dimensions. Experiments that use multiple slices from a single tissue sample—such as a region of a brain, heart or tumor—are difficult to synthesize into a complete picture of the cell types in the tissue.

Summary: Researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson’s associated destruction of dopaminergic cells.

Neurodegenerative diseases damage and destroy neurons, ravaging both mental and physical health. Parkinson’s disease, which affects over 10 million people worldwide, is no exception. The most obvious symptoms of Parkinson’s disease arise after the illness damages a specific class of neuron located in the midbrain. The effect is to rob the brain of dopamine—a key neurotransmitter produced by the affected neurons.

In new research, Jeffrey Kordower and his colleagues describe a process for converting non-neuronal cells into functioning neurons able to take up residence in the brain, send out their fibrous branches across neural tissue, form synapses, dispense dopamine and restore capacities undermined by Parkinson’s destruction of dopaminergic cells.

Jesper AndersonNo. Nobody can “leave their body”. There is no evidence what so ever that this is possible.

What can be done is, copy many of your attributes and create a copy which behaves very much like you. But that’s simply an advanced method of writing a book. I… See more.

Craig Everett JonesAlthough neurons are much like transistors, our emotions are not just ones and zeroes. We feel things in our gut. I think singularity fans are grossly underestimating the dependencies between human consciousness and organic physiology. And, your b… See more.

Continue reading “COVID-19 in 2022—The Beginning of the End or the End of the Beginning?” »

How psilocybin evolved has more to do with sending insects on terrifying trips than it does making Phish sound good.

Research by Dr. Silvia de Santis and Dr. Santiago Canals, both from the Institute of Neurosciences UMH-CSIC (Alicante, Spain), has made it possible to visualize for the first time and in great detail brain inflammation using diffusion-weighted Magnetic Resonance Imaging. This detailed “X-ray” of inflammation cannot be obtained with conventional MRI, but requires data acquisition sequences and special mathematical models. Once the method was developed, the researchers were able to quantify the alterations in the morphology of the different cell populations involved in the inflammatory process in the brain.

An innovative strategy developed by the researchers has made possible this important breakthrough, which is published today in the journal Science Advances and which may be crucial to change the course of the study and treatment of neurodegenerative diseases.

The research demonstrates that diffusion-weighted MRI can noninvasively and differentially detect the activation of microglia and astrocytes, two types of brain cells that are at the basis of neuroinflammation and its progression.