Specifically, the researchers examined how THC administered through edibles, a common consumption method, influenced epigenetic changes in crucial areas for fetal development, including the placenta, fetal lung, brain, and heart.
In recent years, the popularity and availability of cannabis has grown significantly, with various consumption methods like edibles gaining traction. However, alongside this trend, there has been a worrisome increase in cannabis use among pregnant women. Unfortunately, our understanding of the detailed effects of using cannabis during pregnancy on the developing child remains limited. Because normal fetal development relies on the crucial process of epigenetic regulation and gene expression modification, it has been suggested that studying the molecular changes linked to cannabis exposure during pregnancy could provide important insights.
To gain a better understanding of the effects of cannabis use during pregnancy, researchers from the Oregon Health & Science University (OHSU) conducted a unique preclinical study that focused on investigating the epigenetic impact of THC, the main active component in cannabis, on fetal development and future health outcomes. The study’s findings were published in the journal Clinical Epigenetics.
With the increasing prevalence of cannabis use, there is a common perception that it is safe. As a result, more pregnant women are turning to cannabis, particularly during the first trimester, to relieve symptoms like morning sickness. However, early pregnancy is a critical time when the developing fetus is most susceptible to environmental factors.
We often believe computers are more efficient than humans. After all, computers can complete a complex math equation in a moment and can also recall the name of that one actor we keep forgetting. However, human brains can process complicated layers of information quickly, accurately, and with almost no energy input: recognizing a face after only seeing it once or instantly knowing the difference between a mountain and the ocean.
These simple human tasks require enormous processing and energy input from computers, and even then, with varying degrees of accuracy.
Creating brain-like computers with minimal energy requirements would revolutionize nearly every aspect of modern life. Quantum Materials for Energy Efficient Neuromorphic Computing (Q-MEEN-C)—a nationwide consortium led by the University of California San Diego—has been at the forefront of this research.
Researchers have long thought that rewards like food or money encourage learning in the brain by causing the release of the “feel-good” hormone dopamine, known to reinforce storage of new information. Now, a new study in rodents describes how learning still occurs in the absence of an immediate incentive.
Led by researchers at NYU Grossman School of Medicine, the study explored the relationship between dopamine and the brain chemical acetylcholine, also known to play a role in learning and memory. Past research had shown that these two hormones compete with one another, so that a boost in one causes a decline in the other. Rewards were thought to promote learning by simultaneously triggering an increase in dopamine and a decrease in acetylcholine.
This sudden hormone imbalance is believed to open a window of opportunity for brain cells to adjust to new circumstances and form memories for later use. Known as neuroplasticity, this process is a major feature of learning as well as recovery after injury. However, the question had remained whether food and other external rewards are the only drivers for this memory system, or whether our brains instead are able to create the same conditions that are favorable to learning without outside help.
Research roadblocks and political debates have delayed progress—but scientists are inching closer to delivering a cure.
Twenty-five years ago, in 1998, researchers in Wisconsin isolated powerful stem cells from human embryos. It was a fundamental breakthrough for biology, since these cells are the starting point for human bodies and have the capacity to turn into any other type of cell—heart cells, neurons, you name it.
National Geographic would later summarize the incredible promise: “the dream is to launch a medical revolution in which ailing organs and tissues might be repaired” with living replacements. It was the dawn of a new era. A holy grail. Pick your favorite cliché—they all got… More.
The isolation of embryonic stem cells in 1998 was a fundamental breakthrough for biology. But despite high hopes new medical treatments based on those stem cells haven’t materialized.
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In this video we will be talking about how to own yourself from the philosophy of Carl Jung. He found his own school of psychology, called analytical psychology and his philosophy is dubbed as “Jungian philosophy”. Within the field of psychology, Jung is famously known for introducing the terms ‘introvert’ and ‘extravert,’ introducing archetypes of the psyche and classifying the boundary between the unconscious and conscious. Our consciousness includes everything that we know about ourselves; the unconsciousness entails everything that is part of us but that we are not aware of. Jung introduced ‘the ego’ and ‘the persona’ as our consciousness, and ‘the shadow’ and ‘the animus and anima’ as the parts that make up our unconsciousness. The shadow is one of the toughest, most intimidating parts to handle: it exists out of everything about ourselves that we dislike, which is why we often refuse to acknowledge it as a part of us. However, what many people don’t know is that not facing the shadow can be an even more intense blow on your self-esteem. But facing it is actually the only way to gain true control over yourself and who you are.
Which is why in this video, we will teach you how you can truly own yourself by doing so-called shadow work in 3 easy steps, from the philosophy of Carl Jung. Step 1 — Meet Your Shadow. Step 2 — Accept Your Shadow. Step 3 — Integrate Your Shadow. I hope you enjoyed watching the video and hope that this wisdom on owning yourself from the philosophy of Carl Jung will be helpful in your life.
Carl Jung, together with Sigmund Freud and Alfred Adler, is one of the 3 founders of psychoanalysis which is a set of psychological theories and methods aiming to release repressed emotions and experiences — in other words, to make the unconscious conscious. Jung was born in Switzerland in 1,875 and died in 1961, leaving behind great works in the fields of psychiatry, anthropology, archaeology, literature, philosophy, psychology and religious studies. Jung had Freud as a mentor for a good part of his career but later he departed from him. This division was painful for Jung and it led him to found his own school of psychology, called analytical psychology as a comprehensive system separate from psychoanalysis. If classical psychoanalysis focuses on the patient’s past, as early experiences are very important in personality development, analytical psychology primarily focuses on the present, on mythology, folklore, and cultural experiences, to try to understand human consciousness. One of the most important ideas of analytical psychology which Jung founded is the process of individuation, which is the process of finding the self — something Jung considered an important task in human development. While he did not formulate a systematic philosophy, he is nonetheless considered a sophisticated philosopher — his school of thought dubbed “Jungian philosophy”. Its concepts can apply to many topics covered in the humanities and the social sciences. A good part of his work was published after his death and indeed there are still some articles written by him that to this day have yet to be published. Some of his most important books are: “Psychology of the Unconscious”, “Man and His Symbols”, “The Archetypes and The Collective Unconscious”, “Modern Man In Search of a Soul”, “The Psychology of the Transference”, “Memories, Dreams, Thoughts”, and “The Relations Between the Ego and the Unconscious”. Besides being a great writer and a researcher, he was also an artist, a craftsman and even a builder. His contribution is enormous and there is a great deal we can learn from his works.
HBP researchers from Germany performed detailed cytoarchitectonic mapping of distinct areas in a human cortical region called frontal operculum and, using connectivity modelling, linked the areas to a variety of different functions including sexual sensation, muscle coordination as well as music and language processing.
The study contributes to the further unravelling of the relationship of the human brain’s structure with function, and is the first proof-of-concept of structural and functional connectivity analysis of the frontal operculum. The newly identified cytoarchitectonic areas have been made publicly available as part of the Julich-Brain Atlas on the EBRAINS platform, inviting for future research to further characterise this brain region.
Based on cell-body stained histological sections in ten postmortem brains (five females and five males), HBP researchers from Heinrich Heine University Düsseldorf and Research Centre Jülich identified three new areas in the frontal operculum: Op5, Op6 and Op7. Each of these areas had a distinct cytoarchitecture. Connectivity modelling showed that each area could be ascribed a distinct functional role.
Immune system changes in the pregnant body that protect the fetus appear to extend to the brain, where a decrease in immune cells late in gestation may factor into the onset of maternal behavior, new research in rats suggests.
In adult female rats that had never given birth—which typically don’t like being around babies—depletion of these cells sped up their care for rat newborns that were placed in their cage.
The loss of these cells, called microglia, and the related uptick in motherly attentiveness were also associated with changes to neuron activity in several regions of the rat brain, suggesting shifts in immune function have a role in regulating maternal behavior.
For many people, they are tiny pests. These fruit flies that sometimes hover over a bowl of peaches or a bunch of bananas. But for a dedicated community of researchers, fruit flies are an excellent model organism and source of information into how neurons self-organize during the insect’s early development and form a complex, fully functioning nervous system.
That’s the scientific story on display in this beautiful image of a larval fruit fly’s developing nervous system. Its subtext is: fundamental discoveries in the fruit fly, known in textbooks as Drosophila melanogaster, provide basic clues into the development and repair of the human nervous system. That’s because humans and fruit flies, though very distantly related through the millennia, still share many genes involved in their growth and development. In fact, 60 percent of the Drosophila genome is identical to ours.
Once hatched, as shown in this image, a larval fly uses neurons (magenta) to sense its environment. These include neurons that sense the way its body presses against the surrounding terrain, as needed to coordinate the movements of its segmented body parts and crawl in all directions.
