Rice University researchers have developed a new implantable sensor, spinalNET, capable of recording the electrical activity of spinal neurons in freely moving subjects. This breakthrough could help unlock the complexities of how spinal neurons process sensory and motor functions, potentially leading to better treatments for spinal cord diseases and injuries.

Implantable technologies have significantly improved our ability to study and even modulate the activity of neurons in the brain. However, neurons in the spinal cord are harder to study in action.

“If we understood exactly how neurons in the spinal cord process sensation and control movement, we could develop better treatments for spinal cord disease and injury,” said Yu Wu, a research scientist who is part of a team of Rice University neuroengineers working on a solution to this problem.

Dr. Matt Lyon, MD: “We are not entirely sure what causes these issues with vision, but we suspect it has to do with a shift in cerebrospinal fluid in the optic nerve sheath. On Earth, gravity pushes that fluid down and it drains out, but in space, it floats up and presses against the optic nerve and retina.”

How does spaceflight affect vision loss in astronauts for both the short and long term? This is what a combined effort between the upcoming Polaris Dawn mission and the Medical College of Georgia (MCG) at Augusta University hopes to achieve as the four-person crew will be using a portable ultrasound machine to study changes in vision during spaceflight. This is especially prevalent since the four-person crew will be traveling in an elliptical orbit 870 miles above the Earth’s surface, exposing them to the Van Allen radiation belt, which is a highly radiated region of space between the Earth and the Moon.

For context, the International Space Station orbits approximately 250 miles above the Earth, and this research holds the potential to further explore the effects of space radiation on the human body, and specifically vision loss.

This study comes as 70 percent of astronauts have been found to suffer from Spaceflight Associated Neuro-Ocular Syndrome (SANS), which is associated with changes within the brain from fluids shifting during spaceflight. Additionally, with NASA planning on sending humans back to the Moon in the next few years, better understanding these changes could help scientists develop ways to combat them, as well.

The city is considering whether to spend federal funds to offer personalized transcranial magnetic stimulation, or PrTMS, to public safety personnel who may feel groggy from poor sleep or want to improve interactions with the public.

Dr. Kevin Murphy explained the drug-free, noninvasive therapy at workshops Monday in Turlock. Therapy performed in a clinic directs magnetic pulses to stimulate electrical activity in neurons in the brain to regulate moods and restore mental well-being. The treatment is tailored for each individual based on an EEG and mapping of brain activity.

Murphy said the benefits for first responders will be fewer injuries and complaints, better sleep and employee satisfaction. The doctor said improved sleep is a common denominator for people who come into the clinic struggling with different issues.

University of Colorado Boulder scientists have discovered that proteins left by COVID-19 can significantly lower cortisol levels in the brain, leading to heightened immune responses to new stressors.

This research, focusing on the neurological symptoms of Long COVID, utilized rats to demonstrate how SARS-CoV-2 antigens persist in the body and alter brain function. This persistent effect could explain the severe and varied symptoms of Long COVID, suggesting potential directions for further research and symptom management strategies.

Understanding covid-19’s long-term impact on the brain.