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Immune molecule alters cellular makeup of human brain organoids

The changes may help explain the link between maternal infection and autism, though more research is needed.

Read the article: https://www.thetransmitter.org/organo

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The Transmitter is an essential resource for the neuroscience community, dedicated to helping scientists at all career stages stay current and build connections. The publication aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. As part of that mission, The Transmitter offers a steady stream of up-to-date news and analysis of the field, written by journalists and scientists.

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#science #research #neuroscience

Neil deGrasse Tyson and Sean Carroll Discuss Controversies in Quantum Mechanics

What is the nature of quantum physics? Neil deGrasse Tyson and comedian Chuck Nice get quantum, exploring Schrodinger’s Cat, electrons, Hilbert Space, and the biggest ideas in the universe (in the smallest particles) with theoretical physicist Sean Carroll.

When did the idea of fields originate? Are fields even real or are they just mathematically convenient? We explore electrons, whether they are a field, and whether they exist at all. We also discuss the wave function, Hilbert Space, and what quantum mechanics really is. Do superpositions always exist?

What would happen if Planck’s Constant were macroscopic? Learn about entangling particles and the longest entanglement distances. If the particles are entangled why would the distance matter? Could we make an internet with quantum entanglement? We break down Schrodinger’s cat, its interpretations, and what the thought experiment really means. Do superpositions always exist?

Are there quantum manifestations in the macro-universe? We explore the microwave background, inflation, and how we discovered that atoms are mostly empty. Sean gives his latest takes on dark matter, dark energy, emergence, and free will. Plus, is dark energy really the cosmological constant?

Timestamps:
00:00 — Introduction: Sean Carroll.
05:28 — The Origin of Feild Theory.
8:26 — Do Electrons Exist?
11:57 — What Really is Quantum Mechanics?
17:30 — What If the Planck Constant Were Macroscopic?
18;45 — Extending Quantum Entanglement.
25:50 — Schrodinger’s Cat \& The Multiverse.
36:16 — Quantum in the Macro Universe.
42:17 — Thoughts on the Dark Universe.

Check out our second channel, @StarTalkPlus.

Alzheimer’s and Dementia | 60 Minutes Full Episodes

From 2018, Dr. Jon LaPook’s groundbreaking report following an Alzheimer’s patient and her caregiver husband for 10 years to document the struggles they face. From 2019, Bill Whitaker’s heartbreaking look at frontotemporal dementia. From July 2017, Lesley Stahl’s examination of efforts to prevent Alzheimer’s. And from this past January, Sharyn Alfonsi’s story on a new approach to brain surgery that could revolutionize the treatment of Alzheimer’s disease.

#news #alzheimer #dementia.

Study: Brain’s Reward System Could Help Heart Attack Recovery

Researchers at the Technion – Israel Institute of technology in Haifa have shown that boosting a person’s mental state could help them recover from a heart attack.

The researchers focused on the reward system – a network in the brain that is activated when a person is motivated or in a positive emotional state – in order to ascertain its impact on recovery from a heart attack, formally known as an acute myocardial infarction (AMI).

They found that activating this system in mice led to better clinical outcomes and reduced scarring of the heart tissue. And while the science behind the link between the brain and the heart is still undefined, the Technion said the study raises hopes of improved treatment for heart disease.

Child Patient Receives World’s First Brain Implant For Rare Form Of Epilepsy

A 13-year-old boy named Oran Knowlson has become the world’s first patient to test out a brain stimulation implant to treat severe epilepsy.

Knowlson was sometimes having hundreds of seizures per day before the device was fitted. His family has stated that he’s already seeing positive changes compared to his condition before implanting the device.

Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy

Several studies have indicated that interrupted epigenetic reprogramming using Yamanaka transcription factors (OSKM) can rejuvenate cells from old laboratory animals and humans. However, the potential of OSKM-induced rejuvenation in brain tissue has been less explored. Here, we aimed to restore cognitive performance in 25.3-month-old female Sprague–Dawley rats using OSKM gene therapy for 39 days. Their progress was then compared with the cognitive performance of untreated 3.5-month-old rats as well as old control rats treated with a placebo adenovector. The Barnes maze test, used to assess cognitive performance, demonstrated enhanced cognitive abilities in old rats treated with OSKM compared to old control animals. In the treated old rats, there was a noticeable trend towards improved spatial memory relative to the old controls.

Does consciousness change the rules of quantum mechanics?

Is your mind blown yet? It should be.

We might never reach the stage where we could perform such an experiment, but thinking about it raises several interesting questions. Why is what we believe about how the world works inconsistent with quantum mechanics? Is there an objective reality, even on the macroscopic scale? Or is what you see different than what I see? Do we have a choice in what we do?

At least one thing is for sure: We are not seeing the whole picture. Maybe our understanding of quantum mechanics is incomplete, or maybe something changes when we scale it to the macroscopic world. But perhaps our role as conscious observers of the world around us is, indeed, unique.