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Menstruation can often come with a degree of discomfort as the uterus prepares to shed. For some, the effects can be horrendous.

It’s estimated that some 5 to 8 percent of women experience moderate to severe symptoms that have a noticeably negative impact on their lives, mental health, and ability to function normally. These premenstrual disorders, or PMDs, affect millions of women globally, yet we know shockingly little about their long-term consequences.

Now, a new nationwide observational study in Sweden has shown that women with PMDs have an increased risk of suicide. In fact, they’re more than twice as likely to die by suicide as women without PMDs. It’s a sobering figure, one that strongly suggests more work needs to be done to understand PMDs, and help the people who suffer from them.

First written: Dec 14, 2018, Last update: Jan 2, 2019.

How can we think about the relationship between the conscious and the physical? In this essay, I wish to propose a way of thinking about it that might be fruitful and surprisingly intuitive, namely to think of consciousness as waves.

The idea is quite simple: one kind of conscious experience corresponds to, or rather conforms to description in terms of, one kind of wave. And by combining different kinds of waves, we can obtain an experience with many different properties in one.

According to the philosopher and cognitive scientist Daniel Dennett, a conscious state is a brain state that is spread out in both space and time. It is spread out in the brain across multiple instances of what Dennett calls “content fixations.” These content fixations are the “multiple drafts” in the theory’s name. Each of these drafts compete for domination in the cognitive system. This domination is what Dennett calls “fame in the brain.” Read more about it here: http://www.scholarpedia.org/article/M

#philosophyofmind

Regular physical activity can offer major rejuvenation powers, helping people retain strength as they age while buffering against illness and injury. As a growing body of research suggests, this includes valuable protection throughout our bodies – including our brains.

According to a new study by researchers from the University of Queensland in Australia, exercise can slow or even prevent cognitive decline in mice, with a “profound and selective effect” on certain types of brain cell.

On top of demonstrating such an intriguing phenomenon in a fellow mammal, the new study also sheds light on how this effect is triggered inside the brains of physically active mice.

Sensory hypersensitivity in mice with the Grin2b gene mutation found in patients is related to hyperactivity of the anterior cingulate cortex (ACC) and hyperconnectivity between the ACC and other brain regions. Credit: Institute for Basic Science.

Director Kim Eunjoon states, “This new research demonstrates the involvement of the anterior cingulate cortex (ACC), which has been known for its deep association with cognitive and social functions, in sensory hypersensitivity in autism.”

The hyperactivity of the ACC was also associated with the enhanced functional connectivity between the ACC and other brain areas. It is believed both hyperactivity and the hyperconnectivity of the ACC with various other brain regions are involved with sensory hypersensitivity in Grin2b-mutant mice.

Enhanced neuron growth in the hippocampus, achieved through exercise or genetic methods, aids mice in forgetting strong, maladaptive memories, offering potential for new treatments for PTSD or drug addiction.

Researchers at the University of Toronto, Canada, and Kyushu University, Japan, discovered that enhancing neuron production and subsequently altering neural connections in the hippocampus—through exercise or genetic intervention—enables mice to forget memories associated with trauma or drugs. The findings, reported in the journal Molecular Psychiatry, could offer a new approach to treating mental health conditions like post-traumatic stress disorder (PTSD) or drug addiction.

PTSD is a mental health condition that can be triggered by experiencing or seeing a traumatic event, such as a natural disaster, serious accident, or attack. Worldwide, around 3.9% of the general population has PTSD, with symptoms including vivid flashbacks and avoidance behaviors, such as staying away from places or pushing away people that remind them of the traumatic event.