The blood-brain barrier has stymied direct treatment of brain disorders. In a recently published study, a researcher reports finding a way to pass therapeutics through the barrier, using readily-available agents.
Category: neuroscience – Page 1,204
IBM’s brain-inspired chip TrueNorth changes how computers ‘think,’ but experts question its purpose
I see great potential for the TrueNorth chip as we migrate towards Quantum & Singularity. TrueNorth is an interim chip that assists researchers, engineers, etc. in their efforts to mimic the human brain’s nuero sensors and processing for robotics, BMI technology, etc.
The new IBM supercomputer chip mimics the human brain by using an architecture with 1 million neurons. Nevertheless, its true purpose remains in question for a project with massive public funding.
Human Brain Project’s Research Platforms Released
30.03.16 — Public Release of Platforms Will Help Advance Collaborative Research in Neuroscience, Medicine, and Computing
The Human Brain Project (HBP) is pleased to announce the release of initial versions of its six Information and Communications Technology (ICT) Platforms to users outside the Project. These Platforms are designed to help the scientific community to accelerate progress in neuroscience, medicine, and computing.
The Platforms released today consist of prototype hardware, software tools, databases and programming interfaces, which will be refined and expanded in a collaborative approach with users, and integrated within the framework of a European Research Infrastructure. The public release of the Platforms represents the end of the Ramp-Up Phase of the HBP and the beginning of the Operational Phase.
Salesforce: Future Works
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Invading the brain to understand and repair cognition
April 5, 2016, New York — People are using brain-machine interfaces to restore motor function in ways never before possible — through limb prosthetics and exoskletons. But technologies to repair and improve cognition have been more elusive. That is rapidly changing with new tools — from fully implantable brain devices to neuron-eavesdropping grids atop the brain — to directly probe the mind.
These new technologies, being presented today at the Cognitive Neuroscience Society (CNS) annual conference in New York City, are mapping new understandings of cognition and advancing efforts to improve memory and learning in patients with cognitive deficits.
Eavesdropping on neurons
“A new era” of electrophysiology is now upon us, says Josef Parvizi of Stanford University who is chairing the CNS symposium on the topic. “We have gotten a much sharper view of the brain’s electrophysiological activity” using techniques once relegated to science fiction.
Scientists identify neurons that help you process emotions
Scientists just got one step closer to understanding the nuts and bolts of how your mind handles emotions. An MIT team has identified two neural connections in the brain’s amygdala regions that process positive and negative emotional events. By tagging neuron groups with a light-sensitive protein, they discovered that the neurons form parallel but complex channels that respond differently to given situations. Some neurons within one of those connection will be excited by a feeling, while others will be inhibited — the combination of those reactions in a given channel may determine the emotion you experience.
It’s still early days. The researchers need to explore specific neuron populations in-depth to see how they’re connected, and they have to clearly define the larger neural circuits. If they succeed, though, they might help explain how mental health issues operate. Anxiety and depression might not fire the neurons that normally go off when you’re happy, for instance. The discoveries could lead to more effective treatments that restore your natural reactions.
Of mice and old men: is the elixir of youth finally coming of age?
Preliminary work suggests that T-cells, which normally target disease, can be genetically engineered to target senescent cells in a wide range of tissues. In future, an infusion of GM blood every few years might be able to keep you going indefinitely (assuming some major advances in treating cancer, Alzheimer’s and heart disease). At which point, the question might be less: “How long have I got?” and more: “How long do you fancy sticking around?”
American scientists have coined the term ‘senolytics’ to describe a new class of drugs designed to delay the ageing process by clearing out doddery cells.