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Delivering Drugs And Removing Toxins With 3-D Printed Micro-Robots

Nanotechnology and 3-D printing are two fields that have huge potential in general, but manipulating this technology and using it in biology also has tremendous and exciting prospects. In a promising prototype, scientists have created micro-robots shaped like fish which are thinner than a human hair, and can be used to remove toxins, sense environments or deliver drugs to specific tissue.

These tiny fish were formed using a high resolution 3-D printing technology directed with UV light, and are essentially aquatic themed sensing, delivery packages. Platinum particles that react with hydrogen peroxide push the fish forward, and iron oxide at the head of the fish can be steered by magnets; both enabling control of where they ‘swim’ off to. And there you have it — a simple, tiny machine that can be customised for various medical tasks.

In a test of concept, researchers attached polydiacetylene (PDA) nanoparticles to the body, which binds with certain toxins and fluoresces in the red spectrum. When these fish entered an environment containing these toxins, they did indeed fluoresce and neutralised the compounds.

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DARPA Deploys Programmable Nanoscale Switches for Next-Generation Electronics

The Defense Advanced Research Projects Agency (DARPA) website reports that two of DARPA’s Young Faculty Award (YFA) recipients have developed nanoscale electronic switches with reprogrammable features, similar to those at play in inter-neuron communication in the brain, which could find uses in next-generation reconfigurable electronic devices and brain-inspired computing.

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A high-performance single-molecule diode

Researchers from Berkeley Lab and Columbia University have created the world’s highest-performance single-molecule diode, using a combination of gold electrodes (yellow) and a “TDO” molecule (purple, with molecular structure on the left) in propylene carbonate, an ionic solution (light blue). The circuit symbols on the right represent a battery and an ammeter (A) to measure current flow. (credit: Brian Capozzi et al./Nature Nanotechnology)

A team of researchers from Berkeley Lab and Columbia University has created “the world’s highest-performance single-molecule diode,” using a combination of gold electrodes and an ionic solution.

The diode’s rectification ratio (ratio of forward to reverse current at fixed voltage) is in excess of 200, “a record for single-molecule devices,” says Jeff Neaton, Director of the Molecular Foundry, a senior faculty scientist with Berkeley Lab’s Materials Sciences Division and the Department of Physics at the University of California Berkeley and a member of the Kavli Energy Nanoscience Institute at Berkeley (Kavli ENSI).

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Millennium Project releases ’2015–16 State of the Future’ report

The Millennium Project released today its annual “2015–16 State of the Future” report, listing global trends on 28 indicators of progress and regress, new insights into 15 Global Challenges, and impacts of artificial intelligence, synthetic biology, nanotechnology and other advanced technologies on employment over the next 35 years.

“Another 2.3 billion people are expected to be added to the planet in just 35 years,” the report notes. “By 2050, new systems for food, water, energy, education, health, economics, and global governance will be needed to prevent massive and complex human and environmental disasters.”

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Synthetic biology – the next big thing

Synthetic biology programming microorganisms to perform some new functions. Genes are made out of DNA; synthetic biology involves inserting synthetic genes that might not have existed before into yeast and reprogramming them to make a new chemistry or things not made naturally by biology. Each gene codes for an enzyme. One can program a new set of enzymes and convert them to intermediate products. If you go through five or even 15 steps, you can get a final product – a polymer, a new drug – creating a chemical factory inside a cell. This is much better than nanotechnology, because in synthetic biology, we get down to molecular size…


Prof. Joseph Jacobson, a leading physicist at the Massachusetts Institute of Technology, is not only the inventor of e-ink but also a mover in creating artificial DNA to eventually cure diseases.

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Super-elastic conducting fibers for artificial muscles, sensors, capacitors

UT Dallas scientists have constructed novel fibers by wrapping sheets of tiny carbon nanotubes to form a sheath around a long rubber core. This illustration shows complex two-dimensional buckling, shown in yellow, of the carbon nanotube sheath/rubber-core fiber. The buckling results in a conductive fiber with super elasticity and novel electronic properties. (credit: UT Dallas Alan G. MacDiarmid Nanotech Institute)

An international research team based at The University of Texas at Dallas has made electrically conducting fibers that can be reversibly stretched to more than 14 times their initial length and whose electrical conductivity increases 200-fold when stretched.

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