Nice write up on magnetic Nano diamonds (NDs)
Here we present a simple physical method to prepare magnetic nanodiamonds (NDs) using high dose Fe ion-implantation. The Fe atoms are embedded into NDs through Fe ion-implantation and the crystal structure of NDs are recovered by thermal annealing.
A biopharmaceutical company focused on the development and commercialization of innovative therapeutics for disease intersections of arthritis, hypertension, and cancer, today announced that they have entered into a license agreement regarding the Company’s SMARTICLES platform for the delivery of nanoparticles including small molecules, peptides, proteins and biologics…
Marina Biotech, Inc. a biopharmaceutical company focused on the development and commercialization of innovative therapeutics for disease intersections of arthritis, hypertension, and cancer, today announced that they have entered into a license agreement regarding the Company’s SMARTICLES platform for the delivery of nanoparticles including small molecules, peptides, proteins and biologics. This represents the first time that the Company’s SMARTICLES technologies have been licensed in connection with nanoparticles delivering small molecules, peptides, proteins and biologics. Under terms of the agreement, Marina could receive up to $90MM in success based milestones. Further details of the agreement were not disclosed.
Interesting read for those interested in inorganic protein (NP) states from a solid to a liquid as the research proves inorganic NPs are in a ‘glassy’ state while transitioning from a solid to a liquid form.
Molecular dynamics simulations of ubiquitin in water/glycerol solutions are used to test the suggestion by Karplus and coworkers that proteins in their biologically active state should exhibit a dynamics similar to ‘surface-melted’ inorganic nanoparticles (NPs). Motivated by recent studies indicating that surface-melted inorganic NPs are in a ‘glassy’ state that is an intermediate dynamical state between a solid and liquid, we probe the validity and significance of this proposed analogy. In particular, atomistic simulations of ubiquitin in solution based on CHARMM36 force field and pre-melted Ni NPs (Voter-Chen Embedded Atom Method potential) indicate a common dynamic heterogeneity, along with other features of glass-forming (GF) liquids such as collective atomic motion in the form of string -like atomic displacements, potential energy fluctuations and particle displacements with long range correlations (‘colored’ or ‘pink’ noise), and particle displacement events having a power law scaling in magnitude, as found in earthquakes. On the other hand, we find the dynamics of ubiquitin to be even more like a polycrystalline material in which the α-helix and β-sheet regions of the protein are similar to crystal grains so that the string -like collective atomic motion is concentrated in regions between the α-helix and β-sheet domains.
Nice.
Researchers at the University of Central Florida (UCF) in the US are combining nanoscience with the principle of Faraday rotation, a magnetic phenomenon discovered in 1845, in a new method for speedy medical tests.
The team applied the magneto-optical technique, called frequency-domain Faraday rotation spectroscopy—or fd-FRS, to characterize proteins, using antibody-functionalized magnetic nanoparticles (MNPs).
Continue reading “Faraday Rotation Spectroscopy for Speedy Medical Testing” »
IBM researchers have established experimental proof of a previously difficult-to-prove law of physics, and in so doing may have pointed to a way to overcome many of the heat management issues faced in today’s electronics. Researchers at IBM Zurich have been able to take measurements of the thermal conductance of metallic quantum point contacts made of gold. No big deal, you say? They conducted measurements at the single-atom level, at room temperature—the first time that’s ever been done.
These measurements confirm the Wiedemann–Franz law, which predicts that the smallest amount of heat that can be carried across a metallic junction — a single quantum of heat — is directly proportional to the quantum of electrical conductance through the same junction. By experimentally confirming this law, it can now be used with confidence to predict and to explore nanoscale thermal and electrical phenomena affecting materials down to the size of few atoms or a single molecule.
Continue reading “Scientists Measure Single Quantum of Heat” »
Published today, using a technique which looks like trampoline, IBM scientists have measured the thermal conductance of metallic quantum point contacts made of gold down to the single-atom level at room temperature for the first time.
As everything scales to the nanoscale, heat – more precisely, the loss of it – becomes an issue in device reliability. To address this, last year, IBM scientists in Zurich and students from ETH Zurich published and patented a technique to measure the temperature of these nano-sized objects at and below 10 nanometer – a remarkable achievement. They called the novel technique scanning probe thermometry (video) and it provided engineers, for the first time, with the ability to map heat loss across a chip, and, more importantly, map heat loss down to the single device level and to map temperature distributions.
I do hope people realize things like nanoparticles/ quantum bio revolutionizing everything in medicine beyond AI. Anyone, not considering in biotech and medical space in general will look dated as improved and advance options are presented that works in conjunction with our systems v. trying kill things or negatively altered our systems like chemo, radioactive treatments, and other drugs do today.
Moderna Therapeutics hopes to turn RNA into a new kind of drug. Can it live up to the hype?
We all love graphene — the one-atom-thick sheets of carbon aren’t just super flexible, harder than diamond, and stronger than steel, they’ve also recently become superconductors in their own right.
But it’s not the only over-achieving nanomaterial out there. Researchers have just simulated a stretched out, one-dimensional (1D) chain of boron, predicting that the material could have even weirder properties than graphene.
Continue reading “Scientists Simulate a New Material That Could Be Even Weirder Than Graphene” »
Graphene cooking oil?
In Brief
Researchers have found a way to turn cheap, everyday cooking oil into the wonder material graphene – a technique that could greatly reduce the cost of making the much-touted nanomaterial.
Graphene is known as the world’s thinnest material due to its 2-D structure, in which each sheet is only one carbon atom thick, allowing each atom to engage in a chemical reaction from two sides. Graphene flakes can have a very large proportion of edge atoms, all of which have a particular chemical reactivity. In addition, chemically active voids created by missing atoms are a surface defect of graphene sheets. These structural defects and edges play a vital role in carbon chemistry and physics, as they alter the chemical reactivity of graphene. In fact, chemical reactions have repeatedly been shown to be favoured at these defect sites.
Interstellar molecular clouds are predominantly composed of hydrogen in molecular form (H2), but also contain a small percentage of dust particles mostly in the form of carbon nanostructures, called polyaromatic hydrocarbons (PAH). These clouds are often referred to as ‘star nurseries’ as their low temperature and high density allows gravity to locally condense matter in such a way that it initiates H fusion, the nuclear reaction at the heart of each star. Graphene-based materials, prepared from the exfoliation of graphite oxide, are used as a model of interstellar carbon dust as they contain a relatively large amount of atomic defects, either at their edges or on their surface. These defects are thought to sustain the Eley-Rideal chemical reaction, which recombines two H atoms into one H2 molecule.
The observation of interstellar clouds in inhospitable regions of space, including in the direct proximity of giant stars, poses the question of the origin of the stability of hydrogen in the molecular form (H2). This question stands because the clouds are constantly being washed out by intense radiation, hence cracking the hydrogen molecules into atoms. Astrochemists suggest that the chemical mechanism responsible for the recombination of atomic H into molecular H2 is catalysed by carbon flakes in interstellar clouds. Their theories are challenged by the need for a very efficient surface chemistry scenario to explain the observed equilibrium between dissociation and recombination. They had to introduce highly reactive sites into their models so that the capture of an atomic H nearby occurs without fail.
Continue reading “Neutrons reveal ‘quantum tunnelling’ on graphene enables the birth of stars” »
