There’s an arms race in medicine—scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, sending the researchers back to square one. In an article published in the Journal of the American Chemical Society, a University of California, Irvine-led team describes the development of a drug candidate that can stop bacteria before they have a chance to cause harm.
“The issue with antibiotics is this crisis of antibiotic resistance,” said Sophia Padilla, a Ph.D. candidate in chemistry and lead author of the new study. “When it comes to antibiotics, bacteria can evolve defenses against them—they’re becoming stronger and always getting better at protecting themselves.”
About 35,000 people in the U.S. die each year from antibiotic-resistant bacterial infections from pathogens like Staphylococcus, while about 2.8 million people suffer from bacteria-related illnesses.
“Acquisitions and programs are moving forward,” an SDA spokesperson said in a statement to SpaceNews, adding that the agency is preparing to release a fresh solicitation for the 10 satellites in the near future.
Tranche 3 Tracking Layer proposals
In parallel with efforts to correct procurement missteps, SDA is advancing the first major satellite acquisition since Tournear’s removal: a 54-satellite procurement for the Tranche 3 Tracking Layer of the Proliferated Warfighter Space Architecture (PWSA). This next-generation missile tracking constellation builds on the foundation of earlier tranches, expanding coverage and improving real-time threat detection capabilities.
An interesting glimpse into the adventurous world of neutrino research in Antarctica!
At McMurdo, Karle must wait for the weather to permit the final leg of the trip. “It is not uncommon to spend several days in McMurdo,” he says. (Karle’s record is 10.) When it’s time, he takes a 3.5-hour flight on a ski-equipped LC-130 aircraft to reach the South Pole. Anyone or anything else that goes to the South Pole must take a similarly tedious route.
There’s a reason scientists have endured the challenges of the climate, the commute and the cost for over half a century—since members of the US Navy completed the original Amundsen–Scott South Pole Station in 1957. Despite all the trouble it takes to get there, the South Pole is an unparalleled environment for scientific research, from climate science and glaciology to particle physics and astrophysics.
This sentiment was echoed by the Particle Physics Project Prioritization Panel in its 2023 report, a decadal plan for the future of particle physics research in the United States. Under its recommendation to “Construct a portfolio of major projects that collectively study nearly all fundamental constituents of our universe and their interactions,” the report prioritized support for five specific projects—two of which are located at the South Pole: cosmic microwave background experiment CMB-S4, the top priority, and neutrino experiment IceCube-Gen2, recommended fifth. Because of the high scientific priority of these projects, the report also urged maintenance of the South Pole site.
The move places True Anomaly in closer proximity to the Space Systems Command in Los Angeles, which oversees billions in Space Force procurement, and taps into Southern California’s deep aerospace talent pool.
The majority of the Long Beach factory will be dedicated to the design, development and manufacturing of new products for the military market, including some being developed for classified U.S. Space Force programs, True Anomaly’s CEO Even Rogers said in an interview.
The company’s headquarters and existing manufacturing facility will remain in Centennial, Colorado, where True Anomaly makes its flagship product, the Jackal satellite, designed to perform in-orbit activities such as rendezvous and proximity operations, and imaging of objects in orbit. The company also developed an operating system software for space domain awareness called Mosaic.