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There’s an arms race in medicine—scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, sending the researchers back to square one. In an article published in the Journal of the American Chemical Society, a University of California, Irvine-led team describes the development of a drug candidate that can stop bacteria before they have a chance to cause harm.

“The issue with antibiotics is this crisis of antibiotic resistance,” said Sophia Padilla, a Ph.D. candidate in chemistry and lead author of the new study. “When it comes to antibiotics, can evolve defenses against them—they’re becoming stronger and always getting better at protecting themselves.”

About 35,000 people in the U.S. die each year from from pathogens like Staphylococcus, while about 2.8 million people suffer from bacteria-related illnesses.

Smart bullets are real—and they might already be in use. From DARPA’s EXACTO to Russia’s secretive programs, guided bullets have come a long way since The Fifth Element. Here’s what we know.

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Cyber Warfare, Explained.
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From influencing elections to disrupting nuclear facilities, the threat of cyber warfare is both ever-present and mostly ignored. Israel, America, and Russia are just a few of the countries in the ever growing cyber arms race.

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Check out all my sources for this video here: https://docs.google.com/document/d/1gaOjUIm3ucnKpQawfkaP_YXn…sp=sharing.

– VIDEO CHAPTERS -
0:00 Intro.
3:13 A New Type of Weapon.
5:50 Zero Days.
12:52 Cyber Warfare 2.0
24:49 Silent Timebombs.
28:18 Outro.

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“Acquisitions and programs are moving forward,” an SDA spokesperson said in a statement to SpaceNews, adding that the agency is preparing to release a fresh solicitation for the 10 satellites in the near future.

Tranche 3 Tracking Layer proposals

In parallel with efforts to correct procurement missteps, SDA is advancing the first major satellite acquisition since Tournear’s removal: a 54-satellite procurement for the Tranche 3 Tracking Layer of the Proliferated Warfighter Space Architecture (PWSA). This next-generation missile tracking constellation builds on the foundation of earlier tranches, expanding coverage and improving real-time threat detection capabilities.

In this interview Jeff Sebo discusses the ethical implications of artificial intelligence and why we must take the possibility of AI sentience seriously now. He explores challenges in measuring moral significance, the risks of dismissing AI as mere tools, and strategies to mitigate suffering in artificial systems. Drawing on themes from the paper ‘Taking AI Welfare Seriously’ and his up and coming book ‘The Moral Circle’, Sebo examines how to detect markers of sentience in AI systems, and what to do about it. We explore ethical considerations through the lens of population ethics, AI governance (especially important in an AI arms race), and discuss indirect approaches detecting sentience, as well as AI aiding in human welfare. This rigorous conversation probes the foundations of consciousness, moral relevance, and the future of ethical AI design.

Paper ‘Taking AI Welfare Seriously’: https://eleosai.org/papers/20241030_T… — The Moral Circle by Jeff Sebo: https://www.amazon.com.au/Moral-Circl?tag=lifeboatfound-20?tag=lifeboatfound-20… Jeff’s Website: https://jeffsebo.net/ Eleos AI: https://eleosai.org/ Chapters: 00:00 Intro 01:40 Implications of failing to take AI welfare seriously 04:43 Engaging the disengaged 08:18 How Blake Lemoine’s ‘disclosure’ influenced public discourse 12:45 Will people take AI sentience seriously if it is seen tools or commodities? 16:19 Importance, neglectedness and tractability (INT) 20:40 Tractability: Difficulties in measuring moral significance — i.e. by aggregate brain mass 22:25 Population ethics and the repugnant conclusion 25:16 Pascal’s mugging: low probabilities of infinite or astronomically large costs and rewards 31:21 Distinguishing real high stakes causes from infinite utility scams 33:45 The nature of consciousness, and what to measure in looking for moral significance in AI 39:35 Varieties of views on what’s important. Computational functionalism 44:34 AI arms race dynamics and the need for governance 48:57 Indirect approaches to achieving ideal solutions — Indirect normativity 51:38 The marker method — looking for morally relevant behavioral & anatomical markers in AI 56:39 What to do about suffering in AI? 1:00:20 Building in fault tolerance to noxious experience into AI systems — reverse wireheading 1:05:15 Will AI be more friendly if it has sentience? 1:08:47 Book: The Moral Circle by Jeff Sebo 1:09:46 What kind of world could be achieved 1:12:44 Homeostasis, self-regulation and self-governance in sentient AI systems 1:16:30 AI to help humans improve mood and quality of experience 1:18:48 How to find out more about Jeff Sebo’s research 1:19:12 How to get involved Many thanks for tuning in! Please support SciFuture by subscribing and sharing! Have any ideas about people to interview? Want to be notified about future events? Any comments about the STF series? Please fill out this form: https://docs.google.com/forms/d/1mr9P… Kind regards, Adam Ford

Book — The Moral Circle by Jeff Sebo: https://www.amazon.com.au/Moral-Circl?tag=lifeboatfound-20?tag=lifeboatfound-20

Jeff’s Website: https://jeffsebo.net/

Eleos AI: https://eleosai.org/

Chapters:

An interesting glimpse into the adventurous world of neutrino research in Antarctica!


At McMurdo, Karle must wait for the weather to permit the final leg of the trip. “It is not uncommon to spend several days in McMurdo,” he says. (Karle’s record is 10.) When it’s time, he takes a 3.5-hour flight on a ski-equipped LC-130 aircraft to reach the South Pole. Anyone or anything else that goes to the South Pole must take a similarly tedious route.

There’s a reason scientists have endured the challenges of the climate, the commute and the cost for over half a century—since members of the US Navy completed the original Amundsen–Scott South Pole Station in 1957. Despite all the trouble it takes to get there, the South Pole is an unparalleled environment for scientific research, from climate science and glaciology to particle physics and astrophysics.

This sentiment was echoed by the Particle Physics Project Prioritization Panel in its 2023 report, a decadal plan for the future of particle physics research in the United States. Under its recommendation to “Construct a portfolio of major projects that collectively study nearly all fundamental constituents of our universe and their interactions,” the report prioritized support for five specific projects—two of which are located at the South Pole: cosmic microwave background experiment CMB-S4, the top priority, and neutrino experiment IceCube-Gen2, recommended fifth. Because of the high scientific priority of these projects, the report also urged maintenance of the South Pole site.

The move places True Anomaly in closer proximity to the Space Systems Command in Los Angeles, which oversees billions in Space Force procurement, and taps into Southern California’s deep aerospace talent pool.

The majority of the Long Beach factory will be dedicated to the design, development and manufacturing of new products for the military market, including some being developed for classified U.S. Space Force programs, True Anomaly’s CEO Even Rogers said in an interview.

The company’s headquarters and existing manufacturing facility will remain in Centennial, Colorado, where True Anomaly makes its flagship product, the Jackal satellite, designed to perform in-orbit activities such as rendezvous and proximity operations, and imaging of objects in orbit. The company also developed an operating system software for space domain awareness called Mosaic.

Ugly.


Job losses are always terrible. This will be a dark and painful day at a space agency that brings so much light and joy to the world. Many of the probationary employees are just starting out their careers and were likely thrilled to land a job at NASA to explore the universe. And then all of that youthful energy and hope was extinguished this week.

It’s possible to view these losses through a couple of lenses.

Yes, NASA is clearly losing some capability with these latest cuts. Many of these hires were likely being counted on to bring new energy into the space agency and become its future discoverers and leaders. And their jobs are being sacrificed for no clear purpose. Is it to increase funding for the military? Is it to pay for tax cuts for the rich? There is a lot of anger that the relatively thin budget line of NASA—less than one-half of 1 percent of the federal budget—is being sliced for such purposes.

WASHINGTON — Space infrastructure company Redwire has secured a contract to provide an additional satellite platform for a U.S. Space Force orbital refueling experiment.

The satellite order, announced Feb. 11, is for a third Mako satellite bus for the Space Force’s Tetra-6 in-orbit refueling experiment scheduled for 2027. The prime contractor for the experiment, Arcfield, had previously ordered two Mako platforms for the Tetra-5 experiment, scheduled for 2025.

The Tetra-5 and Tetra-6 missions represent key tests of in-space refueling capabilities, a sector of the market closely being watched by military and commercial stakeholders as they seek to extend satellite lifespans.