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The Gist: They think they can start wider human trials soon which would last 2 years then have a product in 3 to 4 years.

In this video, Drs Irina and Mike Conboy talk how TPE, therapeutic plasma exchange is already available as an FDA approved procedure and the plans to extend the usage to include more age related diseases. We also discuss the company that they have formed IMU

Our guests today are Drs. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. their discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

Continue reading “Translating Blood Plasma Dilution To Humans | Drs. Irina & Mike Conboy Interrview Series Ep3” | >

In this video, Drs Irina and Mike Conboy talk about the procedure of Neutral Blood Exchange. How it is done and how much blood of the blood is exchanged.

Our guests today are Drs. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. their discovery of the rejuvenating effects of young blood through parabiosis in a seminal paper published in Nature in 2005 paved the way for a thriving field of rejuvenation biology. The Conboy lab currently focuses on broad rejuvenation of tissue maintenance and repair, stem cell niche engineering, elucidating the mechanisms underlying muscle stem cell aging, directed organogenesis, and making CRISPR a therapeutic reality.

Papers mentioned in this video.
Plasma dilution improves cognition and attenuates neuroinflammation in old mice.
https://pubmed.ncbi.nlm.nih.gov/33191466/
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin.
https://pubmed.ncbi.nlm.nih.gov/32474458/
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
https://pubmed.ncbi.nlm.nih.gov/15716955/

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Continue reading “Blood Plasma Dilution w/Saline-Albumin | Drs. Irina & Mike Conboy Interview Series Ep 2” | >

According to recent Occupational Safety and Health Administration data, workers at Amazon fulfillment centers were seriously injured about twice as often as employees in other warehouses. To improve workplace safety, Amazon has been increasing its investment in robotic helpers to reduce injuries among its employees. With access granted for the first time ever, “Sunday Morning” correspondent David Pogue visited the company’s secret technology facility near Seattle to observe some of the most advanced warehouse robots yet developed, and to experience how high-tech tools are being used to aid human workers.

“CBS Sunday Morning” features stories on the arts, music, nature, entertainment, sports, history, science and Americana, and highlights unique human accomplishments and achievements. Check local listings for CBS Sunday Morning broadcast times.

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Continue reading “Meet Amazon’s robots” | >

This product came out months ago with some shocking numbers as to effect. But those effects were in mice tests. 10–20% increase in lifespan and 55% increase in healthspan. It is AKG, Rejuvant, it’s a product you can buy now. There will be a part 2 of this interview so I hope to hear about human data.

Here we present an interview with Tom Weldon the founder and CEO of Ponce de Leon Health, which makes Rejuvant a Calcium AKG based supplement. In this video Tom talks through the process and reasons for selecting CaAKG. He also talks about some of the other results that they found in their tests, especially with respect to mixing different supplements and their combined effects.

This it part 1 of a two part series. In part 2 we talk about his personal experience and on going clinical trials. With that let me start the interview.

Continue reading “CaAKG — The Science Behind Rejuvant | Tom Weldon Interview Series Part I” | >

Signals can be amplified by an optimum amount of noise, but this so-called stochastic resonance is a rather fragile phenomenon. Researchers at AMOLF were the first to investigate the role of memory for this phenomenon in an oil-filled optical microcavity. The effects of slow non-linearity (i.e. memory) on stochastic resonance were never considered before, but these experiments suggest that stochastic resonance becomes robust to variations in the signal frequency when systems have memory. This has implications in many fields of physics and energy technology. In particular, the scientists numerically show that introducing slow non-linearity in a mechanical oscillator harvesting energy from noise can increase its efficiency by tenfold. They published their findings in Physical Review Letters on May 27th.

It is not easy to concentrate on a difficult task when two people are having a loud discussion right next to you. However, complete silence is often not the best alternative. Whether it is some soft music, remote traffic noise or the hum of people chatting in the distance, for many people, an optimum amount of noise enables them to concentrate better. “This is the human equivalent of stochastic resonance,” says AMOLF group leader Said Rodriguez. “In our scientific labs stochastic resonance happens in non-linear systems that are bistable. This means that, for a given input, the output can switch between two possible values. When the input is a periodic signal, the response of a non-linear system can be amplified by an optimum amount of noise using the stochastic resonance condition.”

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Going to eco-extremes to try and save the planet is a great thing to do, but for the majority of us, it’s not an easy thing to do. If everybody makes a few easy little changes to live more sustainably, it’ll have a far bigger impact. And with our range of affordable, everyday solutions, the power of change is in everybody’s hands. The difference isn’t going to be made with a few grand gestures, it’ll be when we all change a bit for good.

#WonderfulEveryday.

To find out more about how IKEA can help you live more sustainably.
visit: https://bit.ly/3oDO9c3

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Continue reading “IKEA — Change a bit for good — TV advert 60 #WonderfulEveryday” | >

Both arts and sciences advance through open-minded iterations. The alternative of staying within traditional boundaries suppresses the exploration of new territories. As Oscar Wilde said: “Consistency is the last refuge of the unimaginative.”

Recognizing the crucial role that imagination plays in advancing both arts and sciences would translate to a culture that fosters innovation by rewarding creativity. Conventional groupthink could be circumvented by populating selection committees of funding agencies with creative individuals rather than with traditional thinkers. A culture of innovation would also benefit from overlap spaces where scientists and artists interact. In deriving his theory of gravity Albert Einstein was inspired by the philosopher Ernst Mach, and Einstein’s new notions of space and time inspired Picasso’s paintings.

Creativity in arts and sciences establishes a backdrop for human existence, as the content it invents gives pleasure and meaning to our lives. The human act of creation is an infinite-sum game, from which all of us benefit. And we can all participate in the creative process, as long as we follow Wilde’s advice: “Be yourself; everyone else is already taken.”

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Global Automobile Infotainment System Market 2020 Industry Research, Review, Growth, Segmentation, Key Players Analysis and Forecast to 2025.

MIT researchers have developed the first fiber with digital capabilities that is able to capture, store, analyze and derive activity after it has been sewn into a shirt.

Yoel Fink, professor of materials science and electrical engineering, lead researcher at the Electronics Research Laboratory and lead author of the study, says digital fibers expand the possibilities for fabrics to uncover the context of hidden patterns in the human body that could be used for monitoring physical performance, medical conclusions and early disease detection are used.

Or you can keep your wedding music one day in the dress you wore on the big day – more on that later.

Continue reading “Engineers create a programmable fiber | MIT News” | >