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What the study shows, the researchers said, is that the interactions between the bacterial populations are as significant to the host’s overall fitness as their presence — the microbiome’s influence cannot be solely attributed to the presence or absence of individual species. “In a sense,” said Jones, “the microbiome’s influence on the host is more than the sum of its parts.”


The gut microbiome — the world of microbes that inhabit the human intestinal tract — has captured the interest of scientists and clinicians for its critical role in health. However, parsing which of those microbes are responsible for effects on our wellbeing remains a mystery.

Taking us one step closer to solving this puzzle, UC Santa Barbara physicists Eric Jones and Jean Carlson have developed a mathematical approach to analyze and model interactions between gut bacteria in fruit flies. This method could lead to a more sophisticated understanding of the complex interactions between human gut microbes.

Their finding appear in the Proceedings of the National Academy of Sciences.

Scientists look around the universe and see amazing structure. There are objects and processes of fantastic complexity. Every action in our universe follows exact laws of nature that are perfectly expressed in a mathematical language. These laws of nature appear fine-tuned to bring about life, and in particular, intelligent life. What exactly are these laws of nature and how do we find them?

The universe is so structured and orderly that we compare it to the most complicated and exact contraptions of the age. In the 18th and 19th centuries, the universe was compared to a perfectly working clock or watch. Philosophers then discussed the Watchmaker. In the 20th and 21st centuries, the most complicated object is a computer. The universe is compared to a perfectly working supercomputer. Researchers ask how this computer got its programming.

How does one explain all this structure? Why do the laws seem so perfect for producing life and why are they expressed in such exact mathematical language? Is the universe really as structured as it seems?

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The constant figures in other situations, making physicists wonder why. Why does nature insist on this number? It has appeared in various calculations in physics since the 1880s, spurring numerous attempts to come up with a Grand Unified Theory that would incorporate the constant since. So far no single explanation took hold. Recent research also introduced the possibility that the constant has actually increased over the last six billion years, even though slightly. If you’d like to know the math behind fine structure constant more specifically, the way you arrive at alpha is by putting the 3 constants h, c, and e together in the equation — As the units c, e, and h cancel each other out, the.

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New research into a very weird type of ice known as Ice VII has revealed how it can form at speeds over 1,000 miles per hour (1,610 kilometres per hour), and how it might be able to spread across yet-to-be-explored alien worlds.

This ice type was only discovered occurring naturally in March, trapped inside diamonds deep underground, and this latest study looks in detail at how exactly it takes shape – apparently in a way that’s completely different to how water usually freezes into ice.

Based on a mathematical model devised by researchers from the Lawrence Livermore National Laboratory in California, there’s a certain pressure threshold across which Ice VII will spread with lightning speed. This process of near-instantaneous transformation is known as homogeneous nucleation.

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Cancer is the poster child of age-related diseases, and a recent study sheds light on why the risk of cancer rises dramatically as we age.

Abstract

For many cancer types, incidence rises rapidly with age as an apparent power law, supporting the idea that cancer is caused by a gradual accumulation of genetic mutations. Similarly, the incidence of many infectious diseases strongly increases with age. Here, combining data from immunology and epidemiology, we show that many of these dramatic age-related increases in incidence can be modeled based on immune system decline, rather than mutation accumulation. In humans, the thymus atrophies from infancy, resulting in an exponential decline in T cell production with a half-life of ∼16 years, which we use as the basis for a minimal mathematical model of disease incidence. Our model outperforms the power law model with the same number of fitting parameters in describing cancer incidence data across a wide spectrum of different cancers, and provides excellent fits to infectious disease data.

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