Here’s Liz Parrish talking about driving down costs, replacing viral vectors, and having all kinds of trouble with the lid of a bottle.
Liz Parrish, founder or Bioviva company, which developing genetic therapy against aging. He first in world tested such genetic therapy on himself and resulting effect make her cells be like 20 years younger.
Event begins in Russian language, but Liz and Roy talks in English.
This is from 2014 but is getting posted around the past couple of days.
““It’s estimated that we’re born with around 20,000 blood stem cells, and at any one time, around 1000 are simultaneously active to replenish blood,” says Holstege. During life, the number of active stem cells shrinks, she says, and their telomeres shorten to the point at which they die –”
She lived to 115, but a study of Hendrikje van Andel-Schipper’s blood hints at factors limiting lifespan.
Amazing!! More time to learn, evolve, love, & explore the world…
A sprawling facility called Timeship in Texas will host 50,000 frozen dead people with one goal — to become the human race’s first immortals.
Activist Saul Kent — one of the minds behind it — is such a passionate believer in ‘cryogenics’ that he froze his own mother’s head in 1988 after her death.
The creators of Timeship — to begin construction shortly — say that the site will stay in place for ‘hundreds of years’, waiting for technology to advance sufficiently to revive the patients inside.
Are pomegranates really the superfood we’ve been led to believe will counteract the aging process? Up to now, scientific proof has been fairly weak. And some controversial marketing tactics have led to skepticism as well. A team of scientists from EPFL and the company Amazentis wanted to explore the issue by taking a closer look at the secrets of this plump pink fruit. They discovered that a molecule in pomegranates, transformed by microbes in the gut, enables muscle cells to protect themselves against one of the major causes of aging. In nematodes and rodents, the effect is nothing short of amazing. Human clinical trials are currently underway, but these initial findings have already been published in the journal Nature Medicine.
As we age, our cells increasingly struggle to recycle their powerhouses. Called mitochondria, these inner compartments are no longer able to carry out their vital function, thus accumulate in the cell. This degradation affects the health of many tissues, including muscles, which gradually weaken over the years. A buildup of dysfunctional mitochondria is also suspected of playing a role in other diseases of aging, such as Parkinson’s disease.
One molecule plays David against the Goliath of aging
The scientists identified a molecule that, all by itself, managed to re-establish the cell’s ability to recycle the components of the defective mitochondria: urolithin A. “It’s the only known molecule that can relaunch the mitochondrial clean-up process, otherwise known as mitophagy,” says Patrick Aebischer, co-author on the study. “It’s a completely natural substance, and its effect is powerful and measurable.”
For all my Precision Medicine, Cancer researchers, and anti-aging friends researchers have id that the mitochondria pathway has been used by cancer cells to exploit for motility and metastasis.
Researchers have identified a new mitochondrial pathway that cancer cells exploit for motility and metastasis—providing a viable, “druggable” target for many different types of tumors. [NIEHS].
Are you an avid supporter of aging research and a keen longevity activist?
The Biogerontology Research Foundation is offering select summer internships for talented individuals. You’d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.
The advertised positions are 3 month internships, with the possibility of continuing afterwards. Free accommodation will be provided for in London, alongside a negotiable salary.
The Biogerontology Research Foundation is a UK based think tank dedicated to aging research and accelerating its application worldwide.
Apply to: [email protected]
Are you an avid supporter of aging research and a keen longevity activist?
The Biogerontology Research Foundation is offering select summer internships for talented individuals. You d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.
Narrated by actor Edward James Olmos, this video describes one of the body’s critical anti-cancer defences – the telomeres. These caps on the ends of our chromosomes shorten each time a cell divides and, when they become too short, trigger the cell to self-destruct. When a cell grows too rapidly, it and all of its descendants normally suffer this fate. Such growths are sometimes called “pre-cancer”. Since our stem cells need to be able to divide without this constraint in order to replace cells lost across the body, they produce the enzyme telomerase to re-extend their telomeres. Unfortunately, a small number of pre-cancerous cells manage to activate their own copies of the telomerase gene, escaping the limit on their growth. SENS Research Foundation is developing therapies to completely block telomere extension in pre-cancerous cells, ensuring the body’s existing defences can function as intended.