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Category: life extension – Page 637

BioViva made headlines last week after announcing that they had become the first company to administer anti-aging gene therapy on a human subject. But missing from the press release was exactly how this would work, the likelihood of its success, and the consequences. How better to address this then, than to hear from ‘Patient 0’ herself, Liz Parrish, the company’s CEO who will be undertaking the treatment.

Yesterday (October 11), she took part in a Reddit AMA (Ask Me Anything), answering a range of questions submitted by Reddit users seeking to find out more about this supposedly pioneering study.

Here are ten things we learned from Liz Parrish’s Reddit AMA.

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Elephants are long-lived, and rather large. Given their size and longevity, scientists have pondered what protects them from cancer for a long time. Thanks to new research, we now know.

A mystery unlocked

Cancer is a big problem. A staggering 1 in 2 people born after 1960 in the UK are predicted to develop cancer at some point in their lifetime. We may be living longer, but the extra years are coming with a raised cancer risk. We may be getting better at treatment, but we’re still finding out exactly what causes it, and how we can prevent it from being a danger altogether.

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Aging is 100% genetic, the reason you go from infant to child to adult to old age.

We need to be scrutinizing Progeria, and the case of the girl who died at 20 and was stuck at the age of a toddler, for the key to the genes that will pause aging. While nanotechnology advances parallel with the cure for all diseases.

Once a bucket of genes linked to aging is removed, the lifespan of cells increases significantly, American scientists discovered during ten years of meticulous research, stressing that the results could be applied to humans.

An “exhaustive, ten-year effort” allowed scientists at the Buck Institute for Research on Aging and the University of Washington to identify some 238 genes which could be targeted to improve human health and possibly extend life spans by 60 percent. The paper was published on Thursday in the journal Cell Metabolism.

Continue reading “Key to longevity? Blocking over 200 genes boosts lifespan” | >

This Week in Science: The First Privately Backed Moon Mission, Using Gene Therapy to Reverse Aging, Artificial Veins and Arteries, and More.

Go here for a clickable image: http://futurism.com/images/this-week-in-science-october-4th-11th-2015/?src=home

Sources
Detecting All Viruses:http://futurism.com/5srzA
Water on Pluto: http://futurism.com/aO2av
Kidney Tissue from Stem Cells: http://futurism.com/DLDON
Converting Algae Blooms into Electrodes: http://futurism.com/w9ez
Fixing Holes in Heart: http://futurism.com/a13Jd
Reversing Aging: http://futurism.com/TjaTL
Private Moon Mission: http://futurism.com/9V626
Artificial Veins: http://futurism.com/rKNzH

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Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures. As a strong proponent of progress and education for the advancement of gene therapy, she serves as a motivational speaker to the public at large for the life sciences. She is actively involved in international educational media outreach and sits on the board of the International Longevity Alliance (ILA). She is an affiliated member of the Complex Biological Systems Alliance (CBSA) whose mission is to further scientific understanding of biological complexity and the nature and origins of human disease. She is the founder of BioTrove Investments LLC and the BioTrove Podcasts which is committed to offering a meaningful way for people to learn about and fund research in regenerative medicine. She is also the Secretary of the American Longevity Alliance (ALA) a 501©(3) nonprofit trade association that brings together individuals, companies, and organizations who work in advancing the emerging field of cellular & regenerative medicine with the aim to get governments to consider aging a disease. I am not a medical doctor or scientist. I can not answer details of therapy. I would like to discuss my experience of creating BioViva, organizing the gene therapies, and then finally being able to administer it to the first human.

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New article on Immortality Bus trip promoting transhumanism with new videos:

It seemed a wild, impossible dream a year ago when I told my wife and young daughters I was going to drive a bus shaped like a coffin across America to raise life extension issues. A week ago, I just finished the second stage of the tour. Soon I’ll begin the third stage from Arizona to Texas, and then across the Bible Belt to Washington DC, where I plan to post a Transhumanist Bill of Rights to the US Capitol building.

If the bus tour seems like a wacky idea–especially for a presidential candidate –it’s because it is. Of course, to transhumanists, a more wacky idea is how most of our nation largely accepts death as a way of life. In the 21st Century, with the amazing science and technology this country has, I don’t believe death needs to be left unconquered. If, as a nation, we would just apply our ingenuity and resources, we could probably conquer death in a decade’s time with modern medicine. That’s precisely the reason why I’m running for president and driving the coffin bus around the country; I want to tell people the important news and get them to support radical technology and longevity science.

2015-10-05-1444064898-3248007-construction.jpg
Construction of the bus in San Francisco — Photo by Zoltan Istvan

Continue reading “Transhumanism Immortality Bus Underway Across America” | >

Today, dementia affects over 46 million people worldwide, by 2050 it will affect more than 131 million people.

Global costs of dementia are estimated at $818 billion. As a result, if dementia care were a country, it would be the world’s 18th largest economy.

Dementias are one of the most expensive diseases for the healthcare system as patients require long-term care with daily activities like washing, getting dressed and eating. It has been estimated that the US health care would save an astonishing 40 billion dollars annually if the age of onset for Alzheimer’s disease was delayed by just 5 years. The estimated annual cost of dementia worldwide is 818 billion dollars, more than the current US defence budget. By 2018 the cost may reach a trillion dollars. Remarkably, if dementia were a country, it would be the 18th largest economy on earth.

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An article written by Dr Michael Fossel talking about telomerase therapy for Alzheimer’s and the work Bioviva and Telocyte are doing to beat this horrific condition.

Reversing Alzheimer’s by Lengthening Telomeres.

There are telomere lengthening compounds available right now for use in research labs. They are not currently available for human use. A group of scientists wants to test these compounds on aging humans now to see if the telomere lengthening effects will induce meaningful age reversal effects.

Telomeres in our cells shorten as we grow older and create cellular havoc that predisposes us to multiple age-related pathologies. These experimental enzymes promote telomere lengthening and in the process offer an intriguing opportunity to circumvent biological aging processes.

Alzheimer’s disease has no cure and evidence points at microglial epigenetic changes being the cause of the inability to remove misfolded proteins in neurons. This proposed study will evaluate the effect the use of hTERT (human telomerase reverse transcriptase) to reverse biomarkers and symptomatology of aging with special target of the microglia cells in Alzheimer’s patients. Misfolded beta amyloids can be effectively cleared by healthy microglia. This could represent a clinical breakthrough in Alzheimer’s treatment that would be immediately available in the clinical setting.

How Alzheimer’s Can Be Prevented and Cured…

Michael Fossel, MD, PhD

As I said in my medical textbook on aging, “If age is a thief, then the greatest treasure we lose is ourselves.”

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