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Researchers have discovered why inflammaging occurs and are working on new treatments. Inflammaging is new medical term for “the chronic inflammation brought on by old age.”


Summary: Inflammaging is a low-grade inflammation brought on by old age. It accelerates the aging process and worsens diseases like cancer and heart disease. Because inflammaging accelerates aging, geroscientists are perfecting a few cures for the condition.

As we age, most of us tend to develop a low-grade chronic inflammation that causes disease and damage throughout the body. Because this low-level inflammation typically accompanies aging, scientists have nicknamed it ‘inflammaging.’ Most geroscientists implicate inflammaging as the cause of many of age-related diseases including diabetes, heart disease, cancer, and dementia. These chronic diseases accelerate aging and shorten our lives.

There is good news, however. Geroscientists feel that reducing inflammaging will eliminate or reduce these diseases. In fact, these anti-aging scientists have developed several potential remedies to solve the problem.

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The number of people who believe—based on data, not faith—that humans can become (almost) immortal is growing, and includes the likes of scientists, billionaires, engineers and billionaire-engineers. For instance, investor Peter Thiel has donated to the anti-ageing cause, in addition to the $500,000 (around ₹3.2 crore) Palo Alto Longevity Prize for anyone who can radically extend the life of a mammal. Larry Ellison, the co-founder of Oracle, too has donated $335 million to scientists studying ageing before he decided to redirect his foundation’s grants toward eliminating polio in 2013.


When, in the future, expensive baubles cease to hold the same novelty they do today, redefined concepts of luxury are what the super-rich can pick from.

By harichandan arakali forbes india staff

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We are doing a series of articles that discuss the Hallmarks of Aging. Published in 2013, this paper is highly regarded in academia and is one of the most cited papers in biology, with an average of being cited once every two days. The paper divides aging into distinct categories (“hallmarks”) of damage to explain how the aging process works and how it causes age-related diseases[1].

Today, we will be looking at one of the primary hallmarks, genomic instability.

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The work, published in the March 8 issue of Science, finally proves that a single anti-aging enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.

The paper shows all of the 117 drugs tested work on the single enzyme through a common mechanism. This means that a whole new class of anti-aging drugs is now viable, which could ultimately prevent cancer, Alzheimer’s disease and type 2 diabetes.

“Ultimately, these drugs would treat one disease, but unlike drugs of today, they would prevent 20 others,” says the lead author of the paper, Professor David Sinclair, from UNSW Medicine, who is based at Harvard University. “In effect, they would slow aging.”

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