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Our Journal Club goes live at 13:00 EST/18:00 UK. Come and watch the live stream on our page where we discuss the latest research. Todays topic is the recent reversal of Epigenetic changes in a living animal via partial cellular programming.


Journal Club live stream to our Facebook page May 30th 13:00 EST/18:00 UK. Join us here live to listen to LEAF and Ocean level Patrons discuss epigenetics and how it relates to aging. It will also be available later to view on Youtube.

This the first of our Monthly Journal Club events hosted by Dr. Oliver Medvedik and guests where we discuss the latest research papers. Journal Club is part of a host of new activities and content this year and is a result of the support we have recieved from the Heroes Campaign currently running on Lifespan.io. If you would like to see more content like this consider becoming a Patron today on the link below:

https://www.lifespan.io/campaigns/join-us-become-a-lifespan-hero/

There is an urgent need to develop better biomarkers and to use the in cost effective packages for accurate measurement of aging.


As human life expectancy has increased throughout the 20th and 21st centuries this has led to a steady increase in the population of older people. With that increase has come the rise of age-related diseases and disabilities. As a result it is becoming ever more important to develop preventative strategies to monitor and maintain health as well as therapies that directly address the various aging processes to delay or prevent the onset of age-related diseases.

One of the ways we can do this is by developing more effective ways to measure how someone is aging, this means developing high quality aging biomarkers. The challenge in creating such biomarkers has always been the fundamental question – what do we measure?

Chronological age is a poor indication of how someone might be aging and is not a good way to ascertain an individual’s risk factor for various age-related diseases. This is simply because everyone ages differently and at different rates. Whilst everyone ages due to the same processes the speed at which these different processes occur can vary between individuals.

Tech world innovator and serial entrepreneur, Naveen Jain, has just launched VIOME, a product that has the potential to forever change the way we look after our health. Riding on the growing awareness in the West that gut health is the foundation for all health, VIOME is a tech product with an artificial intelligence component used towards the in-depth analysis of the gut and metabolic flexibility.

What does that mean? It means that you will know exactly what’s going on in the gut, monitor it quarterly via a simple in-home test, and then employ the recommendations VIOME provides to reach your optimal healthiest living to—ultimately—live a better, longer life free of chronic illness.

But, wait. There’s more.

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Jamie Bartlett’s new book Radicals features #transhumanism in his opening chapter. He’s on a book tour and discusses his time on the Immortality Bus for about 10 minutes in this video below:


Society is badly served by the limited set of ideas which occupy our cultural mainstream. To cope with the increasing pace of change, we need big new ideas. Where might these ideas come from?

In this London Futurists presentation, Jamie Bartlett, Director of the Centre for the Analysis of Social Media at the think tank Demos, shared his thoughts on a number of “radical” outsiders — a variety of individuals, groups and movements who reject the way we live now, and who are attempting to find alternatives.

Future generations are on course to become enveloped in the biggest pension crisis in history, according to the World Economic Forum (WEF), unless policymakers from the world’s leading economies take urgent action.

The Geneva-based organization predicted the challenges of an ageing population could result in the world’s largest economies being forced to tackle a pension time-bomb.

Analysis from WEF showed six countries with the biggest pensions, including the U.S., Canada, U.K., Netherlands, Japan and Australia, as well as the two most densely populated countries in the world – China and India – would face a retirement savings gap in excess of $400 trillion in 2050, up from around $70 trillion in 2015.

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A novel way to target proteins in cells could lead to undruggable diseases being treatable.


Researchers at the university of Dundee have shown that it is possible to target and destroy specific proteins within cells using a new directed protein missile system. This is very interesting as it raises the possibility of targeting aberrant proteins present in diseases that currently have no drug that affects them.

This opens the door to treating a range of diseases as well as potentially being useful in directly targeting proteins involved in the aging process. Before we take a look at the research let’s recap on why proteins are important, what they do and how they relate to aging and diseases.

So what are proteins?

News from the world of rejuvenation biotechs.


Gone are—for now—the golden days when I would publish a new post each week. So, for as long as my schedule is going to be this busy, I’ll have to be content with update bundles. I thought I’d let you know about a few news items and interesting things going on in anti-ageing community.

On June 30 LEAF will host their first Journal Club event, with dr Oliver Medvedik. The topic will be the implications of epigenetic alterations on aging and as a primary aging process.

My topic was #transhumanism and life extension. I’m hoping they might invest in these fields. Former Keynote speakers of this event include Newt Gingrich, Peter Thiel, Andre Agassi, etc. I’ll share a recording of it when I get one. http://familyofficeassociation.com/

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