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Category: life extension – Page 557

Promising Drug Combo Nearly Halves Stroke Risk Says New Report

Summary: A new report provides good news for warding off stroke and hardening of the arteries, two diseases of aging. Combining blood-pressure-lowering drugs with cholesterol-lowering medications reduced first-time strokes by 44%, according to a report by the AHA/ASA. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]

Stroke is the fifth leading cause of death in the US and a disease of aging that grows more prevalent with each birthday.

Now, a report says a new drug regimen promises to cut that risk nearly in half.

The misconception of the two deaths

When we talk about life extension, we mean people living much longer than they do now, and, more importantly, people who are healthier for longer. For example, we mean being 120 with the health of a 30-year-old. Hang on, though—hasn’t a person who is 120 years old already more than lived their life? Hasn’t that person’s time more than come?

News flash: you haven’t lived your life until you’re dead, and even then, you might not necessarily have crossed off all the items on your list. So, no, there is no such thing as an age when you have, by definition, “already lived your life”—not 80, 90, 100, nor any other. What people actually mean when they say that someone has “already lived their life” is that, in their opinion, that person has lived long enough, and thus he or she might as well, and perhaps even should, die.

People who, for one reason or another, fear a world without aging tend to say things like that. Personally, I am much more afraid of a world where other people get to tell you when your life has been long enough, and, consequently, I tend to say that the only one who should have the right to decide when you’ve lived long enough, if ever, is you—not other people, not nature, not an imaginary greater good. You.

These researchers argue there is no upper limit to our lifespan

Researchers say there is not an upper limit to human lifespan. However, a new report from the CDC suggests that both sides of the debate may be missing the point.

Summary: Several researchers say there is not an upper limit to human lifespan, contradicting studies which point to a maximum human lifespan. However, a new report from the CDC suggests that both sides of the debate may be missing the point. [This article first appeared on LongevityFacts. Author: Brady Hartman. ]

While many studies have set an upper limit on human lifespan at around 115 to 120 years, other researchers argue that there is no upper limit. This article presents both sides of the debate over the existence of a maximum human lifespan.

Upper Limit to Human Lifespan

The trouble started last year when several new studies announced that human lifespan is limited to about 115 – 120 years.

Does Aging Have a Reset Button?

Part of Vittorio Sebastiano’s job is to babysit a few million stem cells. The research professor of reproductive biology at Stanford University keeps the cells warm and moist deep inside the Lorry I. Lokey Stem Cell Research Building, one of the nation’s largest stem cell facilities. He’s joined there by an army of researchers, each with their own goals. His own research program is nothing if not ambitious: He wants to reverse aging in humans.

Stem cells are the Gary Oldman of cell types. They can reprogram themselves to carry out the function of virtually any other type of cell, and play a vital role in early development. This functional reprogramming is usually accompanied by an age reset, down to zero. Sebastiano figures that if he can separate these different kinds of reprogramming, he can open up a whole new kind of aging therapy. Nautilus caught up with him last month.

Could Klotho Treat Dementia

Researcher Dr. Dena Dubal, from the University of California San Francisco, is considering a new approach to combat neurodegenerative diseases, such as Alzheimer’s disease and dementia, using a protein known as klotho.

Aging is the foundation of age-related diseases

Instead of trying to understand each of these diseases and the complex mechanisms unique to both, she considered what all these conditions have in common; the answer, of course, is aging.

Altered Carbon Premiere Viewing Party SF w Aubrey/Life Extension

Viewing party of one of the most highly-anticipated science fiction stories onto the screen. Richard Morgan’s Altered Carbon on Netflix. Introduction speech by Dr. Aubrey de Grey, famous proponent of innovative biotechnologies.

Watch the premiere alongside other fans and talk about what you would do if you could live another 100 years.

https://www.netflix.com/title/80097140

Cancer ‘vaccine’ eradicates tumors in mice, holds promise in humans

Summary: Activating T cells in tumors destroyed most traces of cancer in mice, and had ‘amazing, bodywide effects,’ Stanford University researchers reported. The researchers are recruiting lymphoma patients to test the approach in a clinical trial. [This article first appeared on the website LongevityFacts.com. Author: Brady Hartman. ]

Researchers at the Stanford University School of Medicine used two novel agents to activate immune system T cells in tumors. The immune-boosting treatment destroyed most traces of cancer in mice the researchers reported in a study published on Jan. 31 in the journal Science Translational Medicine.

Injecting tiny amounts of two immune-stimulating agents directly into solid tumors in mice can eradicate all traces of cancer in the rodents, including distant metastases, the researchers found. The novel approach works for many different types of cancers, including tumors that arise spontaneously, the new study found.