Lifeboat Foundation

As he sits stroking his Rip Van Winkle-worthy beard, it’s easy to see how de Grey’s achieved this “kind of a spiritual leader-status,” as he calls it. He dives easily into intricate explanations of two research projects unfolding in the lab down the hall, eagerly describing how one studies mitochondrial mutations, which are thought to cause an increase in oxidative stress. The other looks at atherosclerosis, the narrowing and hardening of artery walls. If we understood more about this buildup, the logic goes, we could better clean it up before too much damage is done.

Though he attends lab meetings and oversees the SENS’s research, his primary task is convincing the general public that death is, in fact, bad and that we should be doing everything we can to stop it. This focus on messaging suits him just fine. “I’m not in this to do science for the sake of doing science,” he says. “I’m in it for the ultimate goal.” He does a “ridiculous” amount of media, he says, and gives around 50 talks a year, from Vietnam to the Czech Republic.

Back in April, at a San Francisco blockchain conference called Block 2 the Future, de Grey began his talk with a disclaimer: “I probably ought to start by emphasizing that I don’t know fuck-all about cryptocurrencies. I am really only here because I have apparently quite a significant fan base in this community, and I am delighted that I do.”

Continue reading “The Bitcoiners Who Want to Defeat Death” »

Given the chance, there are very few of us who wouldn’t want to slow down the aging process. Chasing that fountain of youth is a major branch of medical science at the moment, and a hardy little worm known as C. elegans is probably the most prolific test subject. Now, a team at Scripps Research has found that blocking a particular enzyme can extend the lifespan of these worms by almost half again.

Today, we want to spotlight a new publication that charts the senescence-associated secretory phenotype (SASP), which consists of the various secreted signals given out by senescent cells during aging.

Senescent cells and the SASP

As we get older, an increasing number of our cells enter into a state known as senescence. They cease dividing and supporting the tissues and organs of which they are part and, instead, secrete a range of harmful chemical signals. This cocktail of harmful signals is known as the senescence-associated secretory phenotype (SASP).

Continue reading “A New Database for Senescent Cells” »

Clinical trials to remove senescent cells have now begun.

Eric Kilhstrom (Director of Aging Analytics Agency and former Interim Director of the £98 million Healthy Ageing Industrial Strategy Challenge Fund) is interviewed about the agency’s recent “Longevity Industry in Israel Landscape Overview 2019” report.

New report shows that Israel’s academic and business ecosystem is the optimal base for an internationally recognized longevity industry hub.

Continue reading “Israel fast becoming world hub of aging industry” »

We submitted the Longevity Peace Prize, worth $5 million dollars to be awarded to any longevity activist(s) in the next 5 years who can get a major world government or the UN to declare “aging a disease” as a policy and to help reverse regulatory hurdles on life extension research. Hopefully, this early version of a prize may one day become reality. https://xprize.org/

April is gone, and before we move on to May, let’s take a look back at the highlights of last month in the rejuvenation world.

LEAF News

Continue reading “Rejuvenation Roundup April 2019” »

undoing-aging.org/…/judy-campisi-presenting-at-undoing-agin…

More info on Forever Healthy: forever-healthy.org