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Category: life extension – Page 372

Homeroom with Sal & David Sinclair, PhD — Tuesday, July 14

Want to learn how we age and whether we can slow or even reverse aging? David Sinclair, PhD, professor of genetics at Harvard Medical School, says in his book “Lifespan” that aging is a disease, and that disease is treatable. Tune in to Homeroom with Sal on Tuesday at noon PT to get your questions answered by a leading expert on aging and age-associated diseases.

For more information visit: keeplearning.khanacademy.org

Khan Academy is a nonprofit with a mission to provide a free, world-class education for anyone, anywhere. If you’d like to contribute, please visit:
https://www.khanacademy.org/donate?utm_source=youtube&utm_me…oolclosers

Researchers discover 2 paths of aging and new insights on promoting healthspan

Aging/longevity link!

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan.

The research is described July 17 in the journal Science.

Our lifespans as humans are determined by the aging of our individual . To understand whether different cells age at the same rate and by the same cause, the researchers studied aging in the budding yeast Saccharomyces cerevisiae, a tractable model for investigating mechanisms of aging, including the aging paths of skin and .

Sperm discovery reveals clue to genetic ‘immortality’

New insights into an elusive process that protects developing sperm cells from damage in growing embryos, sheds light on how genetic information passes down, uninterrupted, through generations.

The study identified a protein, known as SPOCD1, which plays a key role in protecting the early-stage precursors to sperm, known as , from damage in a developing embryo.

During their development, germ cells undergo a reprogramming process that leaves them vulnerable to rogue genes, known as jumping genes, which can damage their DNA and lead to infertility.

Geneticists sequence the complete human X chromosome for the first time

For the first time, scientists have determined the complete sequence of a human chromosome, namely the X chromosome, from ‘telomere to telomere’. This is truly a complete sequencing of a human chromosome, with no gaps in the base pair read and at an unprecedented level of accuracy.

A step closer towards the complete blueprint of a human being

The Human Genome Project was a 13-year-long, publicly funded project initiated in 1990 with the objective of determining the DNA sequence of the entire human genome.

For The First Time, Scientists Have Completely Sequenced a Human Chromosome

In 2003, history was made. For the first time, the human genome was sequenced. Since then, technological improvements have enabled tweaks, adjustments, and additions, making the human genome the most accurate and complete vertebrate genome ever sequenced.

Nevertheless, some gaps remain — including human chromosomes. We have a pretty good grasp of them in general, but there are still some gaps in the sequences. Now, for the first time, geneticists have closed some of those gaps, giving us the first complete, gap-free, end-to-end (or telomere-to-telomere) sequence of a human X chromosome.

The accomplishment was enabled by a new technique called nanopore sequencing, which enables ultra-long-reads of DNA strands, providing a more complete and sequential assembly.

Lifespan.io Launches Lifespan News

In this premier episode of Lifespan News, Brent Nally discusses Unity Biotechnology’s human trials of novel senolytic drugs, including a Phase 2 human trial of a senolytic drug for knee osteoarthritis; two proteins that allow LDL cholesterol to enter our cells; Ponce de Leon Health and epigenetic age reversal; the reason why naked mole rats are so resistant to cancer; XPrize adding longevity to its impact roadmaps; and a promo code for Ending Age-Related Diseases 2020, our upcoming online conference.

You can get your ticket to EARD2020 at https://www.eventbrite.com/e/ending-age-related-diseases-202…4918805703

0:00 Introduction
0:51 Unity Biotechnology Updates
1:43 Proteins & LDL: https://www.lifespan.io/news/two-proteins-allow-ldl-cholesterol-into-our-cells/
2:17 Epigenetic Age Reversal: https://www.lifespan.io/news/pilot-study-results-suggest-epi…-reversal/
3:18 Naked Mole Rat
4:11 XPrize and Longevity: https://www.xprize.org/articles/future-of-longevity-blog-post
4:50 Additional Information and Outro

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LEAF / Lifespan.io is a 501©(3) nonprofit organization. Everything we’ve done thus far and everything we will do in the future is thanks to your support — please stand with us to fight the diseases of aging and increase healthy human lifespan.
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#LifespanNews #LifespanIO #Unity #XPrize #Senolytics

The Booming Space Economy

The current market is expected to balloon to $1.0-$1.5 trillion in the next 20 years. Not even the anti-aging industry is worth that much!

The next decade is going to be an important one, with declining costs & advanced technology propelling the space economy to new highs. We have never been closer to the final frontier.

Reprinted with permission from the author.

Faisal Khan is a prolific Canada-based tech blogger and influencer. He is the founder and editor of the Technicity publication which focuses on technical, scientific and financial knowledge sharing. Follow him on Twitter @fklivestolearn.

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