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Dr. Harold Katcher, PhD — Chief Scientific Officer — Yuvan Research — Rejuvenative Plasma Fractions

Studying Novel Plasma Fractions For Age-Related Diseases And Systemic Rejuvenation — Dr. Harold Katcher Ph.D., Chief Scientific Officer, Yuvan Research Inc.


Dr. Harold Katcher is the Chief Scientific Officer at Yuvan Research Inc., a biotech company exploring the development of novel, young plasma fraction rejuvenation treatments in mammals.

Most recently Dr. Katcher was the Academic Director for Natural Sciences for the Asian Division of the University of Maryland Global Campus and throughout his career, Dr. Katcher has been a pioneer in the field of cancer research, and in the development of modern aspects of gene hunting and sequencing (including as one of the discoverers of the breast cancer gene BRCA1) as part of Myriad Genetics, and carries expertise in bioinformatics, chronobiology, and biotechnology.

Dr. Katcher has thousands of citations in the scientific literature, with publications ranging from protein structure to bacteriology, biotechnology, bioinformatics and biochemistry.

Dr. Katcher is launching his new book “The Illusion of Knowledge” on September 4th, 2021.

Dr. Hanadie Yousef, Ph.D. Co-Founder & CEO — Juvena Therapeutics — Secretome Derived Therapies

Secretome Derived Regenerative Therapeutics — Dr. Hanadie Yousef Ph.D., Co-Founder & CEO, Juvena Therapeutics


Dr. Hanadie Yousef, Ph.D. is a Scientist, Co-Founder and CEO of Juvena Therapeutics (https://www.juvenatherapeutics.com/), a regenerative medicine company developing protein therapeutics to promote tissue regeneration and increase healthspan, to prevent, reverse, and cure degenerative diseases.

For over 17 years, Dr. Yousef elucidated mechanisms of aging and developed methods for tissue regeneration supported by multiple awards, fellowships and grants. Her discoveries were published in top publications that include Nature Medicine and led to several issued patents which laid the foundation of Juvena Therapeutics’ venture-backed, drug discovery and pre-clinical development platform.

Dr. Yousef earned a BS in Chemistry, summa cum laude, from Carnegie Mellon University, a PhD in Molecular and Cell Biology from UC Berkeley as an NSF graduate research fellow, pursued a 5-year postdoctoral fellowship in Neurology at Stanford School of Medicine, and conducted R&D at Regeneron and Genentech.

Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study

ABOVE: MAPT, one of the genes linked to both heavy drinking and neurodegenerative diseases, codes for the protein tau (blue in this illustration) inside a neuron. NATIONAL INSTITUTE ON AGING/ NATIONAL INSTITUTES OF HEALTH

Some genetic risk factors for alcohol use disorder overlap with those for neurodegenerative diseases like Alzheimer’s, scientists reported in Nature Communications on August 20. The study, which relied on a combination of genetic, transcriptomic, and epigenetic data, also offers insight into the molecular commonalities among these disorders, and their connections to immune disfunction.

“By meshing findings from genome wide association studies… ith gene expression in brain and other tissues, this new study has prioritized genes likely to harbor regulatory variants influencing risk of Alcohol Use Disorder,” writes David Goldman, a neurogenetics researcher at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), in an email to The Scientist. “Several of these genes are also associated with neurodegenerative disorders—an intriguing connection because of alcohol’s ability to prematurely age the brain.”

How To Live To 150: The Science & Tech Of Growing Young | Lifespan.io Interview

Out today.


Sergey Young is a longevity investor and visionary with the XPRIZE his mission to extend healthy lifespans of at least one billion people. To do that, Sergey founded Longevity Vision Fund to accelerate life extension technological breakthroughs and to make longevity affordable and accessible to all.

Today Sergey is launching his new book! : “The Science and Technology of Growing Young.” https://www.amazon.com/Science-Technology-Growing-Young-Brea…atfound-20

Watch more videos with Sergey on his Youtube Channel.
https://www.youtube.com/channel/UCaBpzdvA76UpZ72_Env-ZFw.

In this interview, Elena Milova of Lifespan.io is discussing with Sergey his work and the practical tips from the book to help readers live longer healthier.

Dr. Tia Rains, Ph.D., VP Customer Engagement & Strategic Development, Ajinomoto Health & Nutrition

Innovation in the amino-sciences for health, wellness, and aging — dr. tia rains phd, VP customer engagement & strategic development, ajinomoto.


Dr. Tia Rains, Ph.D., is Vice President of Customer Engagement & Strategic Development at Ajinomoto Health & Nutrition North America, Inc. (https://www.ajihealthandnutrition.com/), a division of Japanese food and biotechnology Ajinomoto Corporation (https://www.ajinomoto.com/), which produces seasonings, cooking oils, frozen foods, beverage, sweeteners, amino acids, and pharmaceuticals.

Dr. Rains has over 20 years of experience working on health and wellness initiatives within the food and beverage sector, and enjoys working at the intersection of nutrition research and communications, with the goal of advancing credible research in nutrition and developing truthful messaging on new research results in the context of the body of nutrition evidence.

Dr. Rains most recently headed up the Egg Nutrition Center (ENC) as it’s Executive Director.

Prior to joining ENC, Dr. Rains was the Senior Director of Metabolic Sciences at Biofortis Clinical Research, a global contract research organization specializing in the design and conduct of clinical research for leading food, beverage, and supplement companies around the world.

9 Best Sleep Trackers and Apps for Longevity in 2022

Obstructive sleep apnea is widely “underrecognized and underdiagnosed.” But individuals with moderate to severe sleep apnea have a notable elevated risk of mortality from cancer and stroke compared to individuals without. People with obstructive sleep apnea and parasomnia have higher risks of breast cancer. The same study finds that parasomnia also increases the risk of oral cancer.


Update 8/23/2021: This post has been updated since we originally published it in October 2020. I evaluated additional top sleep trackers and apps for 2,022 added Biostrap, updated the post to reflect most recent pricing, and added additional commentary on my reviews. The post has been cleaned up and links were made current.

I didn’t used to have a harmonious relationship with sleep. In fact, sleep used to be a source of anxiety for me. I have parasomnia, an amalgam of disorders that, occasionally, give me hypnopompic hallucinations Severe hallucinations when waking up from a deep sleep. 0 night terrors Nightmares that lead the dreamer to wake up screaming and thrashing without recollection of the dream itself 0 and, most dangerously, somnambulism The fancy word for ‘sleepwalking.’ 0 which has led me to drive while sleeping and scare the living piss out of my poor husband after we watched Paranormal Activity together (it didn’t help that I was mutely standing over him at 4:15 AM with my eyes wide open).

So it should come as no surprise that I’ve built quite the relationship with my own sleep metrics and have more than a layman’s knowledge of sleep science. Which brings me to this article.

Scientists Discover Small Proteins Regulate the Aging Process

The attachment of the small protein ubiquitin to other proteins (ubiquitination) regulates numerous biological processes, including signal transduction and metabolism / Scientists at the University of Cologne discover the link to aging and longevity.

Scientists have discovered that the protein ubiquitin plays an important role in the regulation of the aging process. Ubiquitin was previously known to control numerous processes, such as signal transduction and metabolism. Prof. Dr. David Vilchez and his colleagues at the CECAD Cluster of Excellence for Aging Research at the University of Cologne performed a comprehensive quantitative analysis of ubiquitin signatures during aging in the model organism Caenorhabditis elegans, a nematode worm which is broadly used for aging research.

This method — called ubiquitin proteomics — measures all changes in ubiquitination of proteins in the cell. The resulting data provide site-specific information and define quantitative changes in ubiquitin changes across all proteins in a cell during aging. A comparison with the total protein content of a cell (proteome) showed which changes have functional consequences in protein turnover and actual protein content during aging. The scientists thus discovered new regulators of lifespan and provide a comprehensive data set that helps to understand aging and longevity. The article, ‘Rewiring of the ubiquitinated proteome determines aging in C. elegans,‘has now been published in Nature.

Northwestern scientists discover remarkable longevity in a subset of mitochondrial proteins

Northwestern Medicine investigators have discovered that a subset of proteins in mitochondria of brain and heart cells are long-lived, supporting the long-term stability of mitochondrial complex architecture.

The study, published in the Journal of Cell Biology, was led by Jeffrey Savas, PhD, assistant professor in the Ken & Ruth Davee Department of Neurology’s Division of Behavioral Neurology, of Medicine the in Division of Nephrology and Hypertension, and of Pharmacology.

Previous work led by Savas discovered that nuclear pore complex proteins in post-mitotic neurons are exceptionally long-lived and persist for months in mouse and rat brains. These proteins, termed long-lived proteins, or LLPs, provide long-term stability and structure to the nuclear pore and subsequently to the nuclear envelope of neurons; however, this concept had never been considered for other intracellular organelles, until now.

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