Toggle light / dark theme

Research involving bowhead whales has suggested that it may one day be possible to extend the human lifespan to 200 years.


From the demigods of Greek mythology to the superheroes of 20th century comic books, we’ve been intrigued by the idea of human enhancement for quite a while, but we’ve also worried about negative consequences. Both in the Greek myths and modern comics and television, each enhanced human has been flawed in some way.

In the area of lifespan enhancement, for instance, Tithonus, though granted eternal life, shrunk and shriveled into a grasshopper, because his immortal girlfriend Eos, forgot to ask Zeus to give him eternal youth. Achilles, while super strong and agile, had a weak spot at the back of his heal, and Superman would lose his power if exposed to “kryptonite”. As for Khan’s people, their physical superiority, both physical and mental, made them overly ambitious, causing a third world war that nearly destroyed humanity in the Star Trek backstory.

CHECK OUT SEASON 1 PLAYLIST: https://www.youtube.com/watch?v=ic9AV4mMbOQ&list=PL_GIV9cvJ8…itbMC34bPF

KEEP THE SHOW ON-AIR! : WWW.PATREON.COM/DEBTNATION

• PLEASE CHECK OUR SPONSOR: WWW.IAMTRANSHUMAN.ORG/

• LINK TO BOOK: https://www.amazon.com/Transhumanism-Handbook-Newton-Lee/dp/…atfound-20

A new study suggests that the enzyme intestinal alkaline phosphatase (IAP) appears to help to prevent age-related loss of intestinal barrier integrity in mice, fruit flies, and potentially humans.

Improving intestinal barrier integrity

There can now be little doubt that the decline of intestinal barrier integrity and the resulting inflammation play an important role in aging. In fact, some researchers suggest that inflammaging, the low-grade chronic background of inflammation seen in older people, has its origin point in the microbiome, the ecosystem of bacteria living in our guts.

IM’s mission is to offer the most reliable and relevant information on radical life extension and human enhancement.

IM’s is published monthly and features articles and interviews by distinguished scholars, scientists, philosophers, artists, designers, bloggers, speakers, and entrepreneurs.

CHECK OUT SEASON 1 PLAYLIST: https://www.youtube.com/watch?v=ic9AV4mMbOQ&list=PL_GIV9…itbMC34bPF

KEEP THE SHOW ON-AIR! : WWW.PATREON.COM/DEBTNATION

• PLEASE CHECK OUR SPONSOR: WWW.IAMTRANSHUMAN.ORG/
• LINK TO BOOK: https://www.youtube.com/redirect?q=https%3A%2F%2Fwww.amazon.…yQqqBCoW44

This episode of Debt Nation is sponsored by Thrivous, the human enhancement company (https://thrivous.com). Thrivous develops and distributes advanced nootropic and geroprotector dietary supplements, to enhance cognition and promote healthy aging. Each nutrient and each dose is based on multiple human studies. And all quality control is completely open source.

A 102-year-old woman has recovered from coronavirus in the northern Italian city of Genoa after spending more than 20 days in hospital, doctors who treated her and her nephew told CNN.

“We nicknamed her ‘Highlander’ – the immortal,” said doctor Vera Sicbaldi, who treated Italica Grondona in the San Martino hospital in Genoa.

“Italica represents a hope for all the elderly facing this pandemic.”

His work transformed the mind-set of scientists, launching a new field in the science of aging when he demonstrated that identifying and manipulating genes could lengthen life span.

Although Johnson’s research has led to drug development to slow the effects of age-related diseases, he has yet to find the secret to stop aging. Now the soft-spoken redheaded scientist is running out of time as he confronts his own mortality.


In 1987, scientist Tom Johnson’s team identified the first gene that affects aging. Today, he still works in his lab as he deals with incurable Lewy body dementia.

For the first time, scientists have reprogrammed cells from a 114-year-old woman into induced pluripotent stem cells (iPS cells), a move which they describe as a significant step toward understanding “the underlying mechanisms of extreme longevity and disease resistance.”

iPS cells are adult cells that have been genetically reprogrammed into an embryonic stem cell-like state and are able to give rise to any of the specialized cell types of the body, whether it’s neurons, blood cells, or heart cells.

Until this new project, researchers weren’t even certain whether they could create viable iPS cells from someone so elderly, let alone a supercentenarian. Now they have shown it’s possible to effectively make these aged cells resemble young pluripotent cells, the researchers believe they might have made a step towards the reversal of cellular aging.