Lifeboat Foundation: Safeguarding Humanity
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Category: life extension – Page 236

Becoming Immortal through Mind Uploading sounds like something that’ll only be possible around the 2100’s. But amazingly, a group of scientists at Nectome are working on giving us the ability to live forever inside of a computer simulation by the end of this decade for around 10000$.

Ray Kurzweil, director of engineering at Google, has long predicted that people will be able to upload their entire brains to computers and become digitally immortal by 2045. Kurzweil made this claim for many years, e.g. during his speech in 2013 at the Global Futures 2045 International Congress in New York, which claims to subscribe to a similar set of beliefs. Mind uploading has also been advocated by a number of researchers in neuroscience and artificial intelligence, such as the late Marvin Minsky.
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TIMESTAMPS:
00:00 The Future is near.
01:46 How this procedure works.
03:31 The development of this technology.
04:24 Is this actually possible to achieve?
06:58 The ethical concerns.
07:40 Last Words.
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#longevity #minduploading #bci

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Aging affects everybody, so it’s easy to understand why so much scientific attention is focused on studying it. Scientists in Canada now claim to have found that telomeres play a different role in cellular aging than previously thought.

One of the main points of interest in anti-aging biology are what’s known as telomeres. These are sections of “junk” DNA that form caps on the ends of chromosomes, protecting important genetic information from damage when a cell divides. But a piece of the telomere is eroded away with each cell division, and when it gets too short the cell stops dividing entirely, entering a dormant state known as senescence. The build-up of these senescent cells contributes to a range of symptoms we associate with aging, such as frailty and age-related diseases.

The implication of this model is that telomeres take on a pre-emptive protection role – they signal to cells to stop dividing as soon as one telomere wears out. But there is evidence to suggest that cell division can continue with as many as five dysfunctional telomeres.

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Cryogenically frozen dead people are held preserved in a clinic at Scottsdale, Arizona in the hope that maybe someday science would be advanced enough to bring them back to life. This unique cryonics clinic is run by Alcor Life Extension Foundation, and surprisingly, many people, including some famous personalities like PayPal co-founder Peter Theil, are actually spending hundreds of thousands of dollars to have their bodies preserved here after death.

The idea of waking up in the future sounds like a great plot for a sci-fi movie or a novel but through cryonics 0 organizations like Alcor are trying to do the same in reality. Max Moore, a futurist and the former CEO of Alcor, believes that people can be rescued from death. “Our view is that when we call someone dead it’s a bit of an arbitrary line. In fact they are in need of a rescue,” he said in an interview. What’s perhaps more surprising is that Alcor is not the only cryonics clinic preserving dead bodies for revival in the future.

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Discussing The Future Of “Seno-Therapeutic” Development — Dr. Judith Campisi, PhD, Professor of Biogerontology, Buck Institute for Research on Aging.

Dr. Judith Campisi, PhD (https://www.buckinstitute.org/lab/campisi-lab/) is a biochemist, cell biologist, and Professor of Biogerontology at the Buck Institute for Research on Aging.

Dr. Campisi received a PhD in biochemistry from the State University of New York at Stony Brook and completed her postdoctoral training in cell cycle regulation at the Dana-Farber Cancer Institute and Harvard Medical School. As an assistant and associate professor at the Boston University Medical School, she studied the role of cellular senescence in suppressing cancer and soon became convinced that senescent cells also contributed to aging. She joined the Lawrence Berkeley National Laboratory as a senior scientist in 1991 working with Dr. Mina Bissell. In 2,002 she started a second laboratory at the Buck Institute. At both institutions, Dr. Campisi established a broad program to understand the relationship between aging and age-related disease, with an emphasis on the interface between cancer and aging.

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Shokrollah Elahi led a new study showing that short-lived white blood cells called neutrophils play a role in impaired T cell functions and counts in people with HIV, as well as the chronic inflammation that is common with the virus. (Photo: Najmeh Bozorgmehr)

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

Neutrophils are a foundational part of the body’s immune system and the most abundant type of white blood cell, making up about 60 to 80 per cent of circulating immune cells in the blood. However, unlike other types of white blood cells, neutrophils are extremely short-lived and cannot be frozen and thawed like other immune cells, making them extremely difficult to examine, said study lead Shokrollah Elahi.

“Neutrophils live for hours to a day or two maximum,” Elahi said. “The body produces a lot of neutrophils, and they do their job and then they die and have to be regenerated in the bone marrow. But despite the fact that neutrophils are the most abundant white blood cells in the blood circulation, their role in the context of HIV has not been very well defined.”

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In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Université de Montréal professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, is caused by irreversible damage to the genome rather than simply by telomere erosion.

This discovery goes against the scientific model most widely adopted in the last 15 years, which is based on one principle: telomeres, caps located at the ends of chromosomes whose purpose is to protect genetic information, erode with each cell division. When they get too short, they tell the cell to stop dividing, thus preventing damage to its DNA. Made dormant, the cell enters senescence.

For this model to be valid, the inactivation of a single should be sufficient to activate the senescence program. Rodier’s laboratory and many others had already observed that several dysfunctional telomeres were necessary.

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A futuristic Pill will soon have the ability to fix any issue with the Human body, cure any disease and even make you live longer. This advancement in Biology is made possible with the help of Artificial Intelligence in the form of Google’s Alphafold 2.0 which solved Protein Folding and created a huge medical database of all proteins for all scientists and researchers to use for free.

Protein folding is the physical process by which a protein chain is translated to its native three-dimensional structure, typically a “folded” conformation by which the protein becomes biologically functional. People like David Sinclair are using it to increase longevity and create future medicine and pills to give human actual superpowers.
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TIMESTAMPS:
00:00 A “Once in a Lifetime” Invention.
00:59 What is Protein Folding?
03:48 How AI Revolutionized the Medical Industry.
05:58 What this means for the future of Medicine.
08:07 Current Problems with AlphaFold 2.0
09:07 Last Words.
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#longevity #medicine #proteins

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To live forever. More and more scientists believe so and in a recent interview, Aubrey De Grey said that there’s a good chance for immortality by 2035. Young people on the other hand have a almost 100% certainty of living forever and never dying.

Reversing aging is no longer science fiction and will soon become a reality with advances in stem cell therapy and advanced injections that stop the aging process in young and old people. So what would a world without death look like? It’s definitely something the government has to look into.

Aubrey de Grey is an English author and biomedical gerontologist. He is the Chief Science Officer of the SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics, Inc. He is editor-in-chief of the academic journal Rejuvenation Research, author of The Mitochondrial Free Radical Theory of Aging and co-author of Ending Aging. He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. He is also an amateur mathematician who has contributed to the study of the Hadwiger–Nelson problem.
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Today, we’re bringing you 10 EMERGING Technologies That Will Change The World. Better stick around for #1 to find out how Elon Musk may have plans to turn us all into human robots some day.
What’s up tech-heads and welcome to another episode of TechJoint! It really feels like we’re already living in the future every day. From 5G connectivity to self-driving cars being even more accessible, innovation is everywhere we look! It can sometimes be hard to imagine a world with even more innovation—a future world. What would it look like? What everyday problems would be solved? It’s a pretty good bet some technologies like artificial intelligence will be in our lives, playing important roles in the future of humankind. Other technologies may seem far fetched, unnecessary and frankly, unattainable. So buckle up, and let’s take a look at these 10 futuristic technologies that are going to change the world as we know it.

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10 EMERGING technologies that will change the world.

10. 10 Voice Assistants.

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