Uploading your mind is not a pathway to immortality. Instead, it will create a possibly hostile digital doppelgänger.
Category: life extension – Page 236
How we can finally win the fight against aging | Aubrey De Grey | TEDxMünchen
For more information on Aubrey de Grey, please visit our website www.tedxmuenchen.de.
Dr. Aubrey de Grey is a biomedical gerontologist based Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501©(3) biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging. He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage.
Twitter: @aubreydegrey.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community.
Lifespan Extension With Calorie Restriction, Fasting, And Circadian Alignment
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Papers referenced in the video:
Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice.
https://www.nature.com/articles/s42255-021-00466-9
Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice.
Natasha Vita-More — Transhumanism, Life Extension & Cryonics
Nicely done Tim!
https://www.timventura.com — Dr. Natasha Vita-More discusses transhumanism, human augmentation, life extension, and cryopreservation, and provides valuable insights into the latest medical advances empowering body augmentation & super-longevity in humans.
Our interview begins with a philosophical discussion of transhumanism, including what it is and why this emerging community is growing so rapidly — as it is driven forward by rapid advances in medical technology and an aging boomer population.
We also discuss the work of Dr. David Sinclair, Liz Parrish and Bioviva Sciences, Alcor, and a collection of notable authors, thinkers, and scientists pushing the boundaries of what it means to be human in the 21st century.
Dr. Natasha Vita-More is a pioneering leader and community organizer in transhumanism, and a proponent of human rights, morphological freedom, and ethical means for human enhancement.
Stanford Neuroscientist: Rejuvenating Aging Brains
The Neuro-Network.
𝐒𝐭𝐚𝐧𝐟𝐨𝐫𝐝 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭: 𝐑𝐞𝐣𝐮𝐯𝐞𝐧𝐚𝐭𝐢𝐧𝐠 𝐀𝐠𝐢𝐧𝐠 𝐁𝐫𝐚𝐢𝐧𝐬
𝙎𝙩𝙖𝙣𝙛𝙤𝙧𝙙 𝙣𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩 𝙏𝙤𝙣𝙮 𝙒𝙮𝙨𝙨-𝘾𝙤𝙧𝙖𝙮, 𝙋𝙝𝘿, 𝙝𝙖𝙨 𝙨𝙥𝙚𝙣𝙩 20 𝙮𝙚𝙖𝙧𝙨 𝙙𝙞𝙨𝙘𝙤𝙫𝙚𝙧𝙞𝙣𝙜 𝙖𝙣𝙙 𝙞𝙣𝙫𝙚𝙨𝙩𝙞𝙜𝙖𝙩𝙞𝙣𝙜 𝙫𝙖𝙧𝙞𝙤𝙪𝙨 𝙢𝙤𝙡𝙚𝙘𝙪… See more.
Stanford neuroscientist Tony Wyss-Coray has spent 20 years unearthing and examining various molecules with neuroprotective and neurodegenerative properties.
Stanford neuroscientist Tony Wyss-Coray, PhD, has spent 20 years discovering and investigating various molecules with neuroprotective and neurodegenerative properties. These molecules are found in or on different cell types in the brain and on the blood vessels abutting it or floating in the blood and the cerebrospinal fluid that bathes it. As we age they become increasingly important.
Wyss-Coray and his colleagues have discovered substances in blood that can accelerate or slow down the brain-aging clock. They’ve identified proteins on blood-vessel surfaces through which some of these molecules can act on the brain, despite the existence of the blood-brain barrier. He’s even shown that older mice look and act younger after receiving young mouse cerebrospinal fluid.
Longevity sirtuin clinical trial teases promising results
New York’s Gorbunova Aging Research Center team is encouraged by frailty results from SIRT6 activator trial.
SIRT6, the so-called “longevity sirtuin” has been making rather a name for itself.
SIRT6 is a protein with an important job. It is vital for both normal base excision repair and double-strand break repair of DNA damage – damage that can lead to genomic instability, which ultimately contributing to aging. These repairs decline with age but can be boosted with SIRT6 [1].
But SIRT6 has another string to its longevity bow; back in 2019, Vera Gorbunova, professor of biology at the University of Rochester, and her team, demonstrated an overexpression of SIRT6 protein leads to extended lifespan. The researchers also showed that the opposite is also true – a deficiency in SIRT6 can cause premature aging [2].
Keith Camhi — Techstars Future of Longevity Accelerator — Innovative Solutions For Older Adults
Innovative Solutions For Unmet Needs Of Older Adults & Their Caregivers — Keith Camhi, Managing Director, Techstars Future of Longevity Accelerator — A Partnership With Melinda Gates Pivotal Ventures.
Keith Camhi is Managing Director, Techstars Future of Longevity Accelerator (https://www.techstars.com/accelerators/longevity), a program, run in partnership with Pivotal Ventures (https://www.pivotalventures.org/), an investment and incubation company created by Melinda French Gates, focusing on innovative solutions to address the unmet needs of older adults and their caregivers. The longevity accelerator core program themes include: Caregiver Support, Care Coordination, Aging in Place, Financial Wellness and Resilience, Preventive Health (both Physical and Cognitive), and Social Engagement.
Keith was previously the SVP of Accelerators for Techstars globally and was inspired to move to the MD role for the longevity program based on having built a venture-backed startup serving older adults himself, having experienced the gaps in America’s care giving infrastructure firsthand, and wanting to support entrepreneurs who are building solutions to address this substantial market opportunity.
Techstars is a global investment business that provides access to capital, one-on-one mentorship, a worldwide network and customized programming for early-stage entrepreneurs. It was founded in 2006 in Boulder, Colorado. As of May 2022, the company had accepted over 2,900 companies into its accelerator programs with a combined market capitalization of US$71 billion.
Prior to Techstars, Keith founded and led the rapid growth of two tech companies in the health and fitness industry – one that reached #20 on the Deloitte Fast 500, and another that made Entrepreneur’s Franchise 500 three times. He has raised over $50 million in venture funding, holds several patents for sensor and machine vision technology, has been an angel investor and LP in several venture funds, and enjoys mentoring promising startups.
TOP 5 Longevity Startups. Who Will Make Us Immortal?
I don’t buy the Jeanne Calment story.
How can we live longer and be healthier? These startups are trying to extend our lives.
✱ Download the Dizraptor app to invest in technologies of the future https://dizraptor.onelink.me/1kIK/samumed.
What’s inside:
00:00 How to make money.
01:42 How has human lifespan increased over history.
03:06 Top 1
04:28 Top 2
05:21 Top 3
05:43 Top 4
06:12 Top 5
06:48 What will the longevity economy change?
#investments #startups #technology #future #investing #preipo #dizraptor #disruptor.
DISCLAIMER:
Yale-developed technology restores cell, organ function in pigs after death
Within minutes of the final heartbeat, a cascade of biochemical events triggered by a lack of blood flow, oxygen, and nutrients begins to destroy a body’s cells and organs. But a team of Yale scientists has found that massive and permanent cellular failure doesn’t have to happen so quickly.
The researchers stressed that additional studies are necessary to understand the apparently restored motor functions in the animals, and that rigorous ethical review from other scientists and bioethicists is required.
The experimental protocols for the latest study were approved by Yale’s Institutional Animal Care and Use Committee and guided by an external advisory and ethics committee.
The OrganEx technology could eventually have several potential applications, the authors said. For instance, it could extend the life of organs in human patients and expand the availability of donor organs for transplant. It might also be able to help treat organs or tissue damaged by ischemia during heart attacks or strokes.