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We live in an amazing age. New medicines, therapies, and treatments come out every day that help people live happier, more meaningful lives. Things are moving so fast it can be hard to keep up. That’s why I follow futurists like Ray Kurzweil who sift through all these innovations. They make it easier for regular people like me to live happier and healthier lives.


Learn from Ray Kurzweil how to easily improve your health and increase your productive lifespan so you can be happier and more fulfilled.

Previous research, oftentimes, has used a narrow definition of what healthy aging can look like.

A recent study from researchers at the University of Toronto has provided new insights into healthy aging by observing two distinct demographics in Canada: immigrant and Canadian-born older adults.

The study’s authors identified several characteristics associated with positive experiences later in life that may contribute to healthy aging, thus revising the definition of what it means to age successfully.

This is a timeline of life extension, attempting to describe significant and illustrative events on the topic, covering advocacy, experiments, some scientific research, and industry. For more content on life extension research, visit Timeline of senescence research and Timeline of calorie restriction.

Almost exactly one year ago, the Longevity Science Foundation emerged onto scene, announcing its bold ambition to work towards a goal of distributing upwards of $1 billion over the next ten years towards funding longevity research. Fast forward one year, and the foundation has announced its first calls for research funding applications: aging clocks and psychedelics in longevity and appointed non-profit fundraising expert Lisa Ireland as its president and CEO.

Longevity. Technology: It’s one thing to say you’re going to spend $1 billion on longevity and quite another to actually make it happen. With more than 25 years’ experience in executive leadership and fundraising roles at non-profit organisations including the United Way, Ireland has the kind of background needed to ensure the LSF delivers on its promise. We caught up with Ireland to learn more about her key objectives at the LSF, and her fresh perspective on the longevity field.

Ireland happily admits to having little knowledge of the longevity field before taking on the role at the LSF. Far from seeing it as a weakness, she views her lack of longevity experience as an advantage in a field that needs to expand its appeal beyond those who are already convinced of its importance.

A scientist shares what he’s learned about living longer, with the help of worms. Scientists are hard at work trying to understand what causes aging and how to help people stay healthy for longer. Biologist Matt Kaeberlein breaks down the science of longevity and tells us how he’s using a robot to test 100,000 aging drugs a year on microscopic worms and a long-term study on the aging of pet dogs. And we’ll leave the lab to visit Willie Mae Avery, the oldest person in Washington D.C., to hear what it’s like to live such a long life.

Portrait of 107-year-old Willie Mae Avery, D.C.‘s oldest living resident.
Credit: Photograph by Rebecca Hale, National Geographic.

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In this video Professor Sebastiano discusses the three most advanced interventions that Turn Bio is working on, for skin, immunology and muscles and when they will be available for human trial.

Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview.

Turn Bio website.
https://www.turn.bio/
Professor Sebastiano’s lab at Stanford.
https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html.
Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells.
https://pubmed.ncbi.nlm.nih.gov/32210226/

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The newly-created Longevity Escape Velocity Foundation (LEV) has released details of the first study in its flagship research programme: Robust Mouse Rejuvenation – Study 1.

Longevity. Technology: A highlight of Longevity Summit Dublin 2022 was Dr Aubrey de Grey’s announcement of his new foundation; LEV Foundation exists to proactively identify and address the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease, and to that end, its flagship research programme is a sequence of large mouse lifespan studies.

Mouse models are significant in aging research for several reasons. Mice and humans share many genetic and physiological similarities, including similar aging-related pathways, and this makes mice a useful model for studying the molecular and cellular processes underlying aging in humans.