A recent paper published in Nature Aging by researchers from Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning.
Machine learning is a subset of artificial intelligence (AI) that deals with the development of algorithms and statistical models that enable computers to learn from data and make predictions or decisions without being explicitly programmed to do so. Machine learning is used to identify patterns in data, classify data into different categories, or make predictions about future events. It can be categorized into three main types of learning: supervised, unsupervised and reinforcement learning.
Scientists have achieved a major breakthrough in combating ageing and age-related diseases. The study by the researchers from Harvard Medical School and Massachusetts Institute of Technology was published in the journal Aging-US.
Humanity’s attempt to prevent ageing: What is the breakthrough?
The researchers have introduced a chemical method through a ‘single pill’ to reprogram body cells, following which the cells effectively return to a younger state.
VIDEO : The company behind GR-1 plans to release 100 units by the end of 2023 mainly targeting robotic R&D labs. GR-1 will be able to carry patients from the bed to wheelchairs and help pick up objects.
Research led by Sichuan University and Huazhong University of Science and Technology, China, has revealed genetic mechanisms that could prolong healthy aging. In the paper, titled “Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span,” published in PLOS Biology, the team details the methods they used to narrow down the potential genomic pathways to a single gene that could be critical to extending healthy human longevity.
With a combination of genetic manipulation, behavioral assays, microscopy techniques, and electrophysiology, the researchers investigated the role of VPS-34 in motor aging. These methods allowed the researchers to gain insights into the molecular mechanisms underlying motor aging and the effects of VPS-34 inhibition on motor function, synaptic transmission, and muscle integrity.
According to the authors, increased life expectancy in recent decades has not been accompanied by a corresponding increase in health span. Aging is characterized by the decline of multiple organs and tissues and motor aging, in particular, leads to frailty, loss of motor independence, and other age-related issues. Identifying mechanisms for therapeutics to delay motor aging is crucial for promoting healthy aging.
Consider it a technological solution to the problem of death.
Over the last couple years, I’ve been writing about creating ghosts — perhaps an inevitability in the midst of a pandemic.
Artur Sychov, founder and CEO of metaverse company Somnium Space, has joined the quest against loss. Using motion capture and voice data, he wants to create duplicate avatars that can move as you moved and speak as you spoke, using your voice.
Starting at 12:40 Liz asks what would your perfect virtual world be like. Not sure what my home world would be like, a Maldives island, an orbital ring colony perhaps. I think my main form of entertainment would be to adventure in the worlds people will create, and perhaps help build them. Someone will detail the 30 million worlds of A Galaxy Far Far Away and go play in it, someone will create a Star Trek Galaxy, D&D, Niven’s Known Space, Potter-verse, LOTR, and so on.
Only a handful of people in the entire world are aware of the work that is going on to increase the lifespan of #humans. Not just in terms of numbers, but also in terms of the quality of life. Most people today are unable to imagine living beyond 80–90, and they absolutely cannot imagine living an active life at 80–90 or beyond, to say nothing of living forever, and leading an active life forever.
But, the reality is that living forever is going to be a reality in the near future. You can catch up on what’s going on in the #longevity space at The Buying Time Podcast.
The Buying Time Podcast is brought to you by two people who are passionate about super-longevity. Sa…ra…va…nan (Saravanan Balakrishnan) is the founder and CEO of Amura Health (amura.ai), a #hospital on the cloud that helps people to beat many #chronic conditions. Liz Parrish is the CEO of BioViva Science, a fore runner in the space of bringing #gene therapy to super-longevity space.
Liz Parrish is a path-maker in the longevity space. She not only established BioViva Sciences, but has tried out her company’s gene #therapy. She is determined not to allow future generations to die of #diseases that plagued previous generations because she is convinced that every disease is curable. If there is no disease, why do you have to die?
In a groundbreaking study, researchers have unlocked a new frontier in the fight against aging and age-related diseases. The study, conducted by a team of scientists at Harvard Medical School, has published the first chemical approach to reprogram cells to a younger state. Previously, this was only achievable using a powerful gene therapy.
On July 12, 2023, researchers from Harvard Medical School, University of Maine and Massachusetts Institute of Technology (MIT) published a new research paper in Aging, titled, “Chemically induced reprogramming to reverse cellular aging.”
The team’s findings build upon the discovery that the expression of specific genes, called Yamanaka factors, could convert adult cells into induced pluripotent stem cells (iPSCs). This Nobel Prize-winning discovery raised the question of whether it might be possible to reverse cellular aging without causing cells to become too young and turn cancerous.
