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Summary: A breakdown in regulatory mechanisms causes iron to build up in the brain during aging, increasing oxidative stress and increasing the risk of age-related cognitive decline, a new study reports.

Source: Northwestern University.

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

Summary: Participating in high levels of physical activities, such as swimming or a game of tennis, once a week helps stave off chronic musculoskeletal pain.

Source: University of Portsmouth.

Those hoping to avoid one of the worst side effects of aging—bone, joint and muscle pain that doesn’t go away—might need to exercise a lot harder and more often than previously believed.

The Neuro-Network.

𝐇𝐨𝐰 ‘𝐃𝐨𝐫𝐦𝐚𝐧𝐭’ 𝐂𝐞𝐥𝐥𝐬 𝐈𝐧 𝐓𝐡𝐞 𝐀𝐠𝐢𝐧𝐠 𝐁𝐫𝐚𝐢𝐧 𝐂𝐨𝐧𝐭𝐫𝐢𝐛𝐮𝐭𝐞 𝐓𝐨 𝐂𝐨𝐠𝐧𝐢𝐭𝐢𝐯𝐞 𝐃𝐞𝐜𝐥𝐢𝐧𝐞

𝘾𝙤𝙜𝙣𝙞𝙩𝙞𝙫𝙚 𝙙𝙚𝙘𝙡𝙞𝙣𝙚 𝙖𝙣𝙙 𝙛𝙤𝙧𝙜𝙚𝙩𝙩𝙞𝙣𝙜 𝙩𝙝𝙞𝙣𝙜𝙨 𝙖𝙨 𝙬𝙚 𝙜𝙚𝙩 𝙤𝙡𝙙𝙚𝙧 𝙞𝙨 𝙖𝙡𝙢𝙤𝙨𝙩 𝙖 𝙧𝙞𝙜𝙝𝙩 𝙤𝙛 𝙥𝙖𝙨𝙨𝙖𝙜𝙚. 𝘼𝙡𝙡… See more.

Continue reading “How ‘Dormant’ Cells In The Aging Brain Contribute To Cognitive Decline” »

Accelerating Research To Prevent & Cure Disease — Dr. Kevin Perrott, Ph.D., Founder & CEO, OpenCures; Co-Founder & Treasurer, SENS Research Foundation

Dr. Kevin Perrott, Ph.D. is Founder and CEO, OpenCures (https://opencures.org/), Adjunct Professor, University of Alberta, Co-Founder and Advisor, Oisin Biotechnologies, President, of Global Healthspan Policy Institute, and Co-Founder and Treasurer, SENS Research Foundation.

Continue reading “Dr Kevin Perrott, PhD — Founder & CEO — OpenCures — Accelerating Research To Prevent & Cure Disease” »

Cam & Dowel Jig is a collection of preset jigs and various tools that are designed to help guide users through designing and constructing their own bespoke furniture.

If you didn’t pick up woodworking as a hobby during the quarantine, chances are you at least tried. In a perfect world, we’d have the know-how to pick up some tools, some pieces of wood, and design our living rooms with our own collection of bespoke furniture. Alas, this is no perfect world so we’ll need some shortcuts. Luckily, David Needham of Kingfisher Design Studio has us covered with an intuitive tool kit designed to streamline bespoke, DIY furniture-building projects.

Dr. Marvin Minsky — A.I. Pioneer & Mind Theorist. Professor of Media Arts and Sciences, MIT, Media Lab http://GF2045.com/speakers.

As soon as we understand how the human brain works, we should be able to make functional copies of our minds out of other materials. Given that everything is made of atoms, if you make a machine, in some sense it is made of the same kinds of materials as brains are made but organized either in very different ways or fundamentally the same ways.

Continue reading “Dr. Marvin Minsky — Facing the Future” »

A team of scientists at Tufts University and Harvard University “have brought us a step closer to the goal of regenerative medicine” by using a drug cocktail to regrow a frog’s amputated legs.

Peer-reviewed study: https://www.science.org/doi/10.1126/sciadv.abj2164

Scientists say they have been able to help frogs regrow their legs for the first time. The next step? Try the procedure on mammals.

Continue reading “Scientists were able to regrow frog legs. Will it pave the way for human regeneration?” »

As Jess Bezos becomes the latest billionaire to attempt to conquer ageing, Gemma Askham meets those on the front line of the quest to delay death.

He’s backing a new biotech company working on “cellular rejuvenation programming.”

It sure looks like Jeff Bezos has plans to cheat death.

The founder and former CEO of Amazon has reportedly made an investment in the freshly launched Altos Labs, a biotech startup focused on “cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine,” according to a January 19 press release. With $3 billion in backing on day one, Altos Labs has hit the ground running with what may be the single largest funding round for a biotech company, according to the Financial Times of London.

Continue reading “Jeff Bezos Is Paying for a Way to Make Humans Immortal” »