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Traditional Japanese Diet associated with Less Brain Shrinkage in Women compared to Western Diet, says research

Cognitive decline and dementia already affect more than 55 million people worldwide. This number is projected to skyrocket over the next few decades as the global population ages.

There are certain risk factors of cognitive decline and dementia that we cannot change – such as having a genetic predisposition to these conditions. But other risk factors we may have more power over – with research showing certain modifiable lifestyle habits, such as smoking, obesity and lack of exercise, are all linked to higher risk of dementia.

What role nutrition plays in preventing cognitive decline and dementia has also been the focus of scientific research for quite some time.

Machine Learning Uncovers New Ways to Kill Bacteria With Non-Antibiotic Drugs

Human history was forever changed with the discovery of antibiotics in 1928. Infectious diseases such as pneumonia, tuberculosis and sepsis were widespread and lethal until penicillin made them treatable.

Surgical procedures that once came with a high risk of infection became safer and more routine. Antibiotics marked a triumphant moment in science that transformed medical practice and saved countless lives.

But antibiotics have an inherent caveat: When overused, bacteria can evolve resistance to these drugs. The World Health Organization estimated that these superbugs caused 1.27 million deaths around the world in 2019 and will likely become an increasing threat to global public health in the coming years.

A National Security Insider Does the Math on the Dangers of AI

Jason Matheny is a delight to speak with, provided you’re up for a lengthy conversation about potential technological and biomedical catastrophe.

Now CEO and president of Rand Corporation, Matheny has built a career out of thinking about such gloomy scenarios. An economist by training with a focus on public health, he dived into the worlds of pharmaceutical development and cultivated meat before turning his attention to national security.

As director of Intelligence Advanced Research Projects Activity, the US intelligence community’s research agency, he pushed for more attention to the dangers of biological weapons and badly designed artificial intelligence. In 2021, Matheny was tapped to be President Biden’s senior adviser on technology and national security issues. And then, in July of last year, he became CEO and president of Rand, the oldest nonprofit think tank in the US, which has shaped government policy on nuclear strategy, the Vietnam War, and the development of the internet.

Significant global variation in COVID-19 guidelines: Most countries recommend at least one treatment that doesn’t work

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

And nearly every recommends at least one treatment proven not to work, the analysis shows.

Significant variations in national COVID-19 have been suspected since the advent of the pandemic, but these haven’t been formally quantified or studied in depth, note the researchers.

Revolutionizing Brain Health: Rice University Unveils Tiny, Implantable Brain Stimulator

Rice University engineers have developed the smallest implantable brain stimulator demonstrated in a human patient. Thanks to pioneering magnetoelectric power transfer technology, the pea-sized device developed in the Rice lab of Jacob Robinson in collaboration with Motif Neurotech and clinicians Dr. Sameer Sheth and Dr. Sunil Sheth can be powered wirelessly via an external transmitter and used to stimulate the brain through the dura ⎯ the protective membrane attached to the bottom of the skull.

The device, known as the Digitally programmable Over-brain Therapeutic (DOT), could revolutionize treatment for drug-resistant depression and other psychiatric or neurological disorders by providing a therapeutic alternative that offers greater patient autonomy and accessibility than current neurostimulation-based therapies and is less invasive than other brain-computer interfaces (BCIs).

Breakthrough in Bioinformatics: AI Predicts Cell Type Transformations

Advances in gene sequencing technology and computing power have significantly increased the availability of bioinformatic data and processing capabilities. This convergence provides an ideal opportunity for artificial intelligence (AI) to develop methods to control cellular behavior.

In a new study, Northwestern University researchers have reaped fruit from this nexus by developing an AI-powered transfer learning approach that repurposes publicly available data to predict combinations of gene perturbations that can transform cell type or restore diseased cells to health.

The study was recently published in the Proceedings of the National Academy of Sciences.

Intermittent Fasting Linked to Vastly Increased Chance of Heart Attack and Stroke

This regimented approach to dieting has helped many people achieve the discipline they need to lose weight, and some research has shown that it can provide a myriad of health benefits, including improved blood pressure.

But a new yet-to-be-published study, presented this week at a meeting of the American Heart Association, suggests that intermittent fasting could have serious consequences for your cardiovascular health.

In an analysis of over 20,000 US adults, the study found that those who eat in just an eight hour window or less per day — thereby fasting for at least 16 hours — had a 91 percent higher chance of dying from heart disease.