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Exercise Spurs Nerve Growth Through Biochemical and Physical Impact

Summary: Researchers found that exercise promotes neuron growth through both biochemical signals (myokines) and physical stretching. Muscle cells, when contracted, release myokines that boost neuron growth and maturity. Furthermore, neurons that were “exercised” through mechanical movement grew just as much as those exposed to myokines.

These findings reveal the dual role of exercise in stimulating nerves, offering hope for developing therapies targeting nerve repair and neurodegenerative diseases. This research opens new avenues in treating nerve damage through “exercise as medicine.”

Salton Sea’s Shrinking Shoreline Linked to Rising Dust Pollution

How is California’s rapidly shrinking Salton Sea contributing to dust pollution in the Golden State? This is what a recent study published in Geographies hopes to address as a team of researchers investigated how much dust pollution is occurring from Salton’s receding shoreline, which has been occurring due to water needs transitioning from the Colorado River to San Diego. This study holds the potential to help researchers better understand water management strategies and how to curtail potential environmental catastrophes from them.

“This research was a direct response to a request from the community, which wanted to be involved in impactful research questions to understand shoreline reduction,” said Dr. Ryan Sinclair, MPH, who is an associate professor of environmental microbiology at Loma Linda University School of Public Health and lead author of the study. “The community wants to be able to live next to a Salton Sea that they’re proud of.”

For the study, the researchers analyzed balloon and satellite images obtained between 2002 and 2021 and estimated the average rate of shoreline loss the Salton Sea experienced during that period. They estimated the shoreline loss averaged 12.53 meters/year between 2002 and 2017 and more than tripled to 38.44 meters/year between 2017 to 2020. They also provided predictions regarding its continued retreat, estimating that between 2030 and 2041 the shoreline is estimated to retreat 22 meters in total. They caution this retreat will contribute to increased dust pollution as a result of the continued shoreline retreat.

Induced pluripotent stem cell-derived macrophages as a platform for modelling human disease

Macrophages are associated with many human diseases but are challenging to study in vivo. Here, Ginhoux and colleagues discuss how iMacs — macrophages generated from induced pluripotent stem (iPS) cells — can enable disease modelling, including through the use of patient-derived iPS cells and 3D organoid co-culture systems. Ultimately, these iMac-based approaches can improve our understanding of macrophage biology in both health and disease.

New Spectral Camera Uses AI to Boost Farm Yields by 20%

A team of EU scientists is developing a new advanced camera that uses photonics to reveal what the eye cannot see. This innovative system is being developed to transform various industries, including vertical farming. It will allow farmers growing crops like salads, herbs, and microgreens to detect plant diseases early, monitor crop health with precision, and optimise harvest times — boosting yields by up to 20%.

A new European consortium funded under the Photonics Partnership is developing a new imaging platform that ensures everything from crops to factory products is of the highest quality by detecting things humans simply cannot.

Called ‘HyperImage’, the project aims to revolutionise quality assurance and operational efficiency across different sectors. This high-tech imaging system uses AI machine learning algorithms to identify objects for more precise decision-making.

NIH study demonstrates long-term benefits of weight-loss surgery in young people

Adolescents see a greater remission of type 2 diabetes compared to adults.

What

Young people with severe obesity who underwent weight-loss surgery at age 19 or younger continued to see sustained weight loss and resolution of common obesity-related comorbidities 10 years later, according to results from a large clinical study funded by the National Institutes of Health (NIH).

There’s a Critical Thing We Can Do to Keep Alzheimer’s Symptoms at Bay

Deep sleep could be key to forestalling slow declines in brain health that may one day lead to Alzheimer’s disease, the most common form of dementia.

In their 2023 study of 62 older, cognitively healthy adults, researchers from the University of California (UC) Berkeley, Stanford University, and UC Irvine in the US found individuals with brain changes associated with Alzheimer’s performed better on memory function tests as they got more deep sleep.

This was irrespective of education and physical activity, two factors along with social connection known to contribute to cognitive resilience in older age.

A portable light system that can digitize everyday objects

Researchers from MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL), the University of California at Berkeley, and Aarhus University have taken an intriguing step forward by fabricating “PortaChrome,” a portable light system and design tool that can change the color and textures…


The portable light system and design tool “PortaChrome” uses UV and RGB LEDs to activate photochromic dye, reprogramming everyday objects like shirts. The MIT CSAIL researchers’ software can help users turn items into multicolor displays of fashion designs and health data.

Dr Päivi Sillanaukee, Special Envoy, Health & Wellbeing, Ministry of Social Affairs & Health Finland

Health Innovation For Prevention And Precision At Scale — Dr. Päivi Sillanaukee, MD, Ph.D. — Special Envoy, Health & Wellbeing, Ministry of Social Affairs and Health Finland.


Dr. Päivi Sillanaukee, MD, Ph.D. is Special Envoy for Health and Wellbeing, Ministry of Social Affairs and Health Finland (https://stm.fi/en/rdi-growth-programm…).

Dr. Sillanaukee has over 20 years of experience at highest civil servant administrative positions, both from government, including roles as Director General at Ministry of Social Affairs and Health, Ambassador for Health and Wellbeing at the Ministry for Foreign Affairs, as well as various additional roles in the public sector at the Municipalities and Special Health care district levels.

Actively participating also in Global Health, Dr. Sillanaukee has chaired and facilitated global multisectoral, multi-partner Health Security collaborations, facilitating capacity building at the country level. She served as Vice chair and member of WHO Executive Board, as Executive President for WHO/Europe Regional Committee, Member of Women in Global Health advocating for Gender Equity in Health, a member of Global Pulse Finland’s health sector advisory board, as Member of Board of Directors, Healthcare Information and Management Systems Society (HIMSS) and Member of the Inaugural Board of Digital Health \& AI Research Collaborative (I-DAIR).

Dr. Sillanaukee has also served as the co-chair of the Alliance for Health Security Cooperation (AHSC) and a member of the Steering Group of the Global Health Security Agenda.

Stem Cell Discovery Highlights importance of DNA Methylation in Cancer

A study led by Umeå University, Sweden, presents new insights into how stem cells develop and transition into specialized cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.

“The discovery opens a new track for future research into developing new and more effective treatments for certain cancers,” says Francesca Aguilo, associate professor at the Department of Molecular Biology at Umeå University and leader of the study in collaboration with various institutions including the University of Pavia, University of Texas Health Science Center at Houston, Universidad de Extremadura, and others.

All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation. Although all cells share the same origin and share the same genetic information, specialized cells use the information in different ways to perform different functions. This process is regulated by genetic and epigenetic mechanisms.