Lifeboat Foundation

Scientists at ETH Zurich isolate genes for a longer, healthier life.

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The UCHealth Eye Center implants first bionic eye in a Colorado resident.

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Glucosepane is one of the most significant mechanisms of aging and yet very few people are working on it!

As we age skin and blood vessels lose their elasticity. People care too much about the skin and too little about the blood vessels, but that is always the way of it. Appearance first and substance later, if at all. Yet you can live inside an aged skin; beyond the raised risk of skin cancer its damaged state arguably only makes life less pleasant, and the present state of medical science can ensure that the numerous age-related dermatological dysfunctions can be kept to a state of minor inconvenience. Loss of blood vessel elasticity, on the other hand, will steadily destroy your health and then kill you. Arterial stiffening causes remodeling of the cardiovascular system and hypertension. The biological systems that regulate blood pressure become dysfunctional as blood vessels depart from ideal youthful behavior, creating a downward spiral of increasing blood pressure and reactions to that increase. Small blood vessels fail under the strain in ever larger numbers, damaging surrounding tissue. In the brain this damage contributes to age-related cognitive decline by creating countless tiny, unnoticed strokes. Ultimately this process leads to dementia. More important parts of the cardiovascular system are likely to fail first, however, perhaps causing a stroke, or a heart attack, or the slower decline of congestive heart failure.

From what is known today, it is reasonable to propose that the two main culprits driving loss of tissue elasticity are sugary cross-links generated as a byproduct of the normal operation of cellular metabolism and growing numbers of senescent cells. Elasticity is a property of the extracellular matrix, an intricate structure of collagens and other proteins created by cells. Different arrangements of these molecules produce very different structures, ranging from load-bearing tissues such as bone and cartilage to elastic tissues such as skin and blood vessel walls. Disrupting the arrangement and interaction of molecules in the extracellular matrix also disrupts its properties. Persistent cross-links achieve this by linking proteins together and restricting their normal range of motion. Senescent cells, on the other hand, secrete a range of proteins capable of breaking down or remodeling portions of the surrounding extracellular matrix, and altering the behavior of nearby cells for the worse.

Continue reading “Scores of Labs Should be Gearing Up to Work on Glucosepane Cross-Link Breakers, But Are They?” »

At MIT, researchers have developed a stretchable bandage-like device capable of sensing skin temperature, delivering drugs transdermally, and containing electronics that include LED lights for displaying information. The various components of the system are designed to work together, for example the drug dispenser activating only when skin temperature is within a certain range and the LEDs lighting up when the drug reservoirs are running low. While this is only a prototype device, it certainly points toward future flexible devices that stay attached to a person’s skin, or even internally, for extended periods of time while providing health data and taking therapeutic actions in an intelligent way.

The device is based on a stretchable hydrogel matrix that reliably holds onto embedded metallic components linked by pliable wires. The hydrogel was made to have a stiffness similar to human soft tissues so that it blends well with the body when attached to it. When wires, drug reservoirs, delivery channels, and electronic components were built-in, the team tested the stretchiness of the final result showing that it maintains functionality even after repeated stress.

Continue reading “Flexible Electronics Used to Make Smart, Temperature Responsive Drug Eluting Patch” »

MOUNTAIN VIEW, Calif. — Google Life Sciences, the Silicon Valley giant’s new foray into health and medicine, announced a new name Monday that slips easily off the tongue but might sound antiquated to a high-tech, life-sciences ear: Verily.

“Verily, I swear,” as Shakespeare wrote in Henry VIII.

The word means “truly” or “certainly.” It dates back to 13th century Middle English and fell out of common use … well, a while ago. It often pops up, however, in the still very popular King James Bible.

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Bodycap develops innovative solutions, promoting new uses and is placed at the service of world players in the health and well-being.

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The world’s first anti-ageing drug will be tested on humans next year in trials which could see diseases like Alzheimer’s and Parkinson’s consigned to distant memory.

Scientists now believe that it is possible to actually stop people growing old as quickly and help them live in good health well into their 110s and 120s.

Although it might seem like science fiction, researchers have already proven that the diabetes drug metformin extends the life of animals, and the Food and Drug Administration in the US has now given the go ahead for a trial to see if the same effects can be replicated in humans.

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London, UK, November, 19, 2015 (PRWEB UK) 19 November 2015.

What matters in beauty is perception. Perception is how you and other people see you, and this perception is almost always biased. Still, healthy people look more attractive despite their age and nationality.

This has enabled the team of biogerontologists and data scientists, who believe that in the near future machines will be able to get a lot of vital medical information about people’s health by just processing their photos, to develop a set of algorithms that can accurately evaluate the criteria linked to perception of human beauty and health where it is most important – the human face. But evaluating beauty and health is not enough. The team’s challenge is to find effective ways to slow down ageing and help people look healthy and beautiful.

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Watch: This amazing, tiny origami robot could revolutionize healthcare around the world » http://cnnmon.ie/1l0VlfQ

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