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Improving Global Resilience Against Emerging Infectious Threats — Dr. Nahid Bhadelia, MD — Founding Director, Center on Emerging Infectious Diseases (CEID), Boston University.


Dr. Nahid Bhadelia, MD, MALD is a board-certified infectious diseases physician who is the Founding Director of BU Center on Emerging Infectious Diseases (https://www.bu.edu/ceid/about-the-cen…) as well an Associate Professor at the BU School of Medicine. She served the Senior Policy Advisor for Global COVID-19 Response for the White House COVID-19 Response Team in 2022–2023, where she coordinated the interagency programs for global COVID-19 vaccine donations from the United States and was the policy lead for Project NextGen, $5B HHS program aimed at developing next generation vaccines and treatments for pandemic prone coronaviruses. She also served as the interim Testing Coordinator for the White House MPOX Response Team. She is the Director and co-founder of Biothreats Emergence, Analysis and Communications Network (BEACON), an open source outbreak surveillance program.

Between 2011–2021, Dr. Bhadelia helped develop and then served as the medical director of the Special Pathogens Unit (SPU) at Boston Medical Center, a medical unit designed to care for patients with highly communicable diseases, and a state designated Ebola Treatment Center. She was previously an associate director for BU’s maximum containment research program, the National Emerging Infectious Diseases Laboratories. She has provided direct patient care and been part of outbreak response and medical countermeasures research during multiple Ebola virus disease outbreaks in West and East Africa between 2014–2019. She was the clinical lead for a DoD-funded viral hemorrhagic fever clinical research unit in Uganda, entitled Joint Mobile Emerging Disease Intervention Clinical Capability (JMEDICC) program between 2017 and 2022. Currently, she is a co-director of Fogarty funded, BU-University of Liberia Emerging and Epidemic Viruses Research training program. She was a member of the World Health Organization(WHO)’s Technical Advisory Group on Universal Health and Preparedness Review (UHPR). She currently serves as a member of the National Academies Forum on Microbial Threats and previously served as the chair of the National Academies Workshop Committee for Potential Research Priorities to Inform Readiness and Response to Highly Pathogenic Avian Influenza A (H5N1) and member of the Ad Hoc Committee on Current State of Research, Development, and Stockpiling of Smallpox Medical Countermeasures.

Dr. Bhadelia’s research focuses on operational global health security and pandemic preparedness, including medical countermeasure evaluation and clinical care for emerging infections, diagnostics evaluation and positioning, infection control policy development, and healthcare worker training. She has health system response experience with pathogens such as H1N1, Zika, Lassa fever, Marburg virus disease, and COVID-19 at the state, national, and global levels.

Dr. Bhadelia has served on state, national, and interagency groups focused on biodefense priority setting, development of clinical care guidelines, and medical countermeasures research. She has served as a subject matter expert to the US Centers for Disease Control and Prevention, Department of Defense (DoD), White House Office of Science and Technology Policy (OSTP) and World Bank. She is an adjunct professor at Fletcher School of Law and Diplomacy at Tufts University since 2016, where she teaches on global health security and emerging pathogens.

Shaping The Culture & Conduct Of Science — Dr. Marcia McNutt Ph.D. — President, National Academy Of Sciences


Dr. Marcia McNutt, Ph.D. is President of the National Academy of Sciences (https://www.nasonline.org/directory-e…), where she also chairs the National Research Council, the operating arm of the National Academies of Sciences, Engineering, and Medicine, and serves a key role in advising our nation on various important issues pertaining to science, technology, and health.

From 2013 to 2016, Dr. McNutt served as editor-in-chief of the Science journals.

Dr. McNutt is a geophysicist who prior to joining Science, was director of the U.S. Geological Survey (USGS) and science adviser to the United States Secretary of the Interior from from 2009 to 2013. During her tenure, the USGS responded to a number of major disasters, including earthquakes in Haiti, Chile, and Japan, and the Deepwater Horizon oil spill.

Dr. McNutt led a team of government scientists and engineers at BP headquarters in Houston who helped contain the oil and cap the well. She directed the flow rate technical group that estimated the rate of oil discharge during the spill’s active phase. For her contributions, she was awarded the U.S. Coast Guard’s Meritorious Service Medal.

A recent study highlights that significant health benefits and molecular adaptations from fasting are detectable after three days.

Recent findings show that prolonged fasting triggers significant and systematic changes across multiple organs in the body. These results highlight potential health benefits that extend beyond weight loss, but they also reveal that these impactful changes only begin to occur after three full days without food.

Health Benefits of Fasting Unveiled.

In a world grappling with a multitude of health threats—ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria—the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where these tests can be done anywhere, by anyone, using a device as small and portable as your smartwatch. To do that, you need microchips capable of detecting miniscule concentrations of viruses or bacteria in the air.

Summary: Researchers have developed a Genetic Progression Score (GPS) using artificial intelligence to predict the progression of autoimmune diseases from preclinical symptoms to full disease. The GPS model integrates genetic data and electronic health records to provide personalized risk scores, improving prediction accuracy by 25% to 1,000% over existing models.

This method identifies individuals at higher risk earlier, enabling timely interventions and better disease management. The framework could also be adapted to study other underrepresented diseases, offering a breakthrough in personalized medicine and health equity.

Scientists have identified a key nucleolar complex that could be instrumental in combating neurodegenerative diseases. This complex plays a critical role in maintaining cellular health by regulating protein homeostasis (proteostasis)—the process by which cells ensure proper protein balance and function.

Research reveals that suppressing this nucleolar complex significantly reduces the toxic effects of proteins associated with Alzheimer’s.

Alzheimer’s disease is a progressive neurological disorder that primarily affects older adults, leading to memory loss, cognitive decline, and behavioral changes. It is the most common cause of dementia. The disease is characterized by the buildup of amyloid plaques and tau tangles in the brain, which disrupt cell function and communication. There is currently no cure, and treatments focus on managing symptoms and improving quality of life.

Per-and polyfluorinated alkyl substances (PFAS) earn their “forever chemical” moniker by persisting in water, soil and even the human brain. This unique ability to cross the blood-brain barrier and accumulate in brain tissue makes PFAS particularly concerning, but the underlying mechanism of their neurotoxicity must be studied further.

To that end, a new study by University at Buffalo researchers has identified 11 genes that may hold the key to understanding the brain’s response to these pervasive chemicals commonly found in everyday items. The paper is published in the journal ACS Chemical Neuroscience.

These genes, some involved in processes vital for neuronal health, were found to be consistently affected by PFAS exposure, either expressing more or less, regardless of the type of PFAS compounds tested. For example, all compounds caused a gene key for neuronal cell survival to express less, and another gene linked to neuronal cell death to express more.

The World Health Organization, WHO, has declared the outbreak of a new coronavirus in China, a global health emergency.

The WHO Director-General Tedros Ghebreyesus made the announcement at a press conference in Geneva.

WHO’s emergency committee on the epidemic had reportedly met Thursday afternoon and recommended designating the outbreak a Public Health Emergency of International Concern, PHEIC.

The World Health Organization (WHO) has declared the mpox outbreak in parts of Africa a public health emergency of international concern.

The highly contagious disease — formerly known as monkeypox — has killed at least 450 people during an initial outbreak in the Democratic Republic of Congo.

It has now spread across parts of central and east Africa, and scientists are concerned about how fast a new variant of the disease is spreading and its high fatality rate.

Research reveals distinct mechanisms underlying neonatal and post-pubertal social behaviors, providing valuable insights for developing targeted early interventions.

Researchers from the University of Texas Health Science Center at San Antonio and Hirosaki University have unveiled significant findings on the development of social behaviors in fragile X syndrome, the most common genetic cause of autism spectrum disorder. The study, published in Genomic Psychiatry, highlights the effects of a specific prenatal treatment on social behaviors in mice.

The researchers found that administering bumetanide—a drug that regulates chloride levels in neurons—to pregnant mice restored normal social communication in newborn pups with the fragile X mutation. However, they also discovered an unexpected outcome: the same treatment reduced social interaction after puberty in both fragile X and typical mice. These findings shed light on the complex and developmental-stage-specific effects of interventions for fragile X syndrome.