Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: health – Page 262

Scientists are on a path to sequencing 1 million human genomes and use big data to unlock genetic secrets

The more data collected, the better the results.

Understanding the genetics of complex diseases, especially those related to the genetic differences among ethnic groups, is essentially a big data problem. And researchers need more data.

1000, 000 genomes

To address the need for more data, the National Institutes of Health has started a program called All of Us. The project aims to collect genetic information, medical records and health habits from surveys and wearables of more than a million people in the U.S. over the course of 10 years. It also has a goal of gathering more data from underrepresented minority groups to facilitate the study of health disparities. The All of Us project opened to public enrollment in 2018, and more than 270000 people have contributed samples since. The project is continuing to recruit participants from all 50 states. Participating in this effort are many academic laboratories and private companies.

Health officials monitoring dozens in US for Ebola

Local health authorities in several parts of the United States are monitoring dozens of travelers for Ebola after the Centers for Disease Control (CDC) ordered airlines to collect information on people who’d been in several western African countries, including Guinea or the Democratic Republic of Congo.

Washington state is monitoring at least 23 travelers. Another 45 are being watched in Ohio. Four people are also being monitored in Oregon.

Ebola is highly contagious and causes severe illness that often leads to death. Symptoms include fever, headache, pain and unexplained bleeding or bruising.

BPA-like chemicals likely causing “alarming” damage to brain cells

Controversy has shrouded the once-common plasticizer BPA since studies started to highlight its links to a whole range of adverse health effects in humans, but recent research has also shown that its substitutes mightn’t be all that safe either. A new study has investigated how these compounds impact nerve cells in the adult brain, with the authors finding that they likely permanently disrupt signal transmission, and also interfere with neural circuits involved in perception.

BPA, or bisphenol A, is a chemical that has been commonly used in food, beverage and other types of packaging for decades, but experts have grown increasingly concerned that it can leech into these consumables and impact human health in ways ranging from endocrine dysfunction to cancer. This came on the back of scientific studies revealing such links dating back to the 1990s, which in turn saw the rise of “BPA-free” plastics as a safer alternative.

One of those alternatives is bisphenol S (BPS), and while it allows plastic manufacturers to slap a BPA-free label on their packaging, more and more research is demonstrating that it mightn’t be much better for us. As just one example, a study last year showed through experiments on mice that just like BPA, BPS can alter the expression of genes in the placenta and likely fundamentally disrupt fetal brain development.

Call for papers abstract submission Space Renaissance

# Just 5 days left to upload an abstract to the SRIC3 Call for Papers! ## We need you to lead the Space Renaissance!

Choose among the following symposia tracks, all of them concurring to a coherent strategy for Space Settlement, kicking off the Civilian Space Development before 2025: * The immense social benefits of expanding Civilization into Outer Space * Civilization risk mitigation: space as the main Knight, defending humanity against the ‘Apocalypse’ multi-crisis * Global collaboration, working with Agencies, Companies, Space Advocacy Associations, United Nations and Governments of Planet Earth to promote Civilian Space Development and the 18th UN SDG * Space Safety: protecting human life and health in space, space debris recovering and reuse, space weather, defense from asteroids * Policies to Enable Communities Beyond Earth: technologies, financing, & Common Law * Earth orbit industrial development * The Moon and Cislunar development * Space Based Solar Power, feeding the Civilian Space Development * Greening the Solar System * Mars, the Asteroids Belt and beyond * A conceptual timetable for the founding steps of Space Settlement * Living, Sport, Art and Culture in Space, a Scifi futurologist–presentist narration * Congress Thesis 1 — Status of civilization and perspective of expansion into outer space * Congress Thesis 2 — A strategy to develop the Space Renaissance, towards 2025.

Web Space Renaissance

Dr. Suzan Murray, D.V.M., Smithsonian / SCBI — Wildlife Care And Combating Emerging Zoonotic Disease

Wildlife Care And Combating Emerging Zoonotic Diseases — Dr. Suzan Murray, D.V.M., D.A.C.Z.M. Smithsonian’s National Zoo and Conservation Biology Institute, Program Director, Global Health Program.

Dr. Suzan Murray, D.V.M., D.A.C.Z.M. is a board-certified zoo veterinarian at the Smithsonian Conservation Biology Institute (SCBI) and serves as both the Program Director of the Global Health Program and as SCBI’s chief wildlife veterinary medical officer.

Dr. Murray leads an interdisciplinary team engaged in worldwide efforts to address health issues in endangered wildlife and combat emerging infectious diseases of global significance, including zoonotic diseases.

Dr. Murray also acts as the Smithsonian liaison to the Foreign Animal Disease Threat and Pandemic Preparedness subcommittees of the White House’s Office of Science and Technology.

Dr. Murray’s work focuses on providing clinical care to free-ranging wildlife, pathogen detection, advanced diagnostics, training of international veterinarians and other health professionals, capacity building, and collaboration in infectious disease research at the human-wildlife-domestic animal interface. She previously served as chief veterinarian for the Smithsonian’s National Zoo and has a wealth of clinical knowledge and experience with wildlife and zoo animals both free-ranging and in human care.

Continue reading “Dr. Suzan Murray, D.V.M., Smithsonian / SCBI — Wildlife Care And Combating Emerging Zoonotic Disease” | >

IBM Bringing Quantum on-Prem for Cleveland Clinic

Fueled by the need for faster life sciences and healthcare research, especially in the wake of the deadly COVID-19 pandemic, IBM and the 100-year-old Cleveland Clinic are partnering to bolster the Clinic’s research capabilities by integrating a wide range of IBM’s advanced technologies in quantum computing, AI and the cloud.

Access to IBM’s quantum systems has so far been primarily cloud-based, but IBM is providing the Cleveland Clinic with IBM’s first private-sector, on-premises quantum computer in the U.S. Scheduled for delivery next year, the initial IBM Quantum System One will harness between 50 to 100 qubits, according to IBM, but the goal is to stand up a more powerful, more advanced, next-generation 1000+ qubit quantum system at the Clinic as the project matures.

For the Cleveland Clinic, the 10-year partnership with IBM will add huge research capabilities and power as part of an all-new Discovery Center being created at the Clinic’s campus in Cleveland, Ohio. The Accelerator will serve as the technology foundation for the Clinic’s new Global Center for Pathogen Research & Human Health, which is being developed to drive research in areas including genomics, single-cell transcriptomics, population health, clinical applications and chemical and drug discovery, according to the Clinic.

An Evolutionary Discovery That “Literally Changes the Textbook”

MSU’s expertise in fish biology, genetics helping researchers rewrite evolutionary history and shape future health studies.

The network of nerves connecting our eyes to our brains is sophisticated and researchers have now shown that it evolved much earlier than previously thought, thanks to an unexpected source: the gar fish.

Michigan State University’s Ingo Braasch has helped an international research team show that this connection scheme was already present in ancient fish at least 450 million years ago. That makes it about 100 million years older than previously believed.

Dr. Lee Chae — Co-Founder / CTO, Brightseed — Re-Connect People and Plants, For Health & Wellness

Using Artificial Intelligence And Plant Biology, To Re-Connect People and Plants, For Health & Wellness — Dr. Lee Chae, Ph.D., Co-Founder & CTO, Brightseed.

Dr. Lee Chae, Ph.D., is a Co-Founder and Chief Technology Officer at Brightseed, a novel life sciences company, merging the tools of plant biology and artificial intelligence, with a goal of enabling a healthier future by re-illuminating and re-activating the connections between people and plants.

Dr. Chae is a seasoned R&D technology developer and has designed advanced discovery methodologies for food technology, agricultural biotech, bio-medicine, and synthetic biology. He has been a principal scientist of multiple discoveries, including machine-learning driven discovery of novel nutritional bio-actives in plants and computationally guided identification of plant-based proteins for food.

With as Ph.D in Plant Biology, Computational and Genomic Biology, from University of California, Berkeley, Dr. Chae was also a founding member of the Quantitative Biosciences Institute, and did Post-Doctoral Research at the Carnegie Institution at Stanford.

Prior to Brightseed, Dr. Chae served as the VP of R&D at Hampton Creek, a company developing and marketing plant-based alternatives to conventionally-produced food products.

Continue reading “Dr. Lee Chae — Co-Founder / CTO, Brightseed — Re-Connect People and Plants, For Health & Wellness” | >

First Infection of Human Cells During Spaceflight Analyzed

“Before we began this study, we had extensive data showing that spaceflight completely reprogrammed Salmonella at every level to become a better pathogen,”

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

Now, in the first study of its kind, Cheryl Nickerson, lead author Jennifer Barrila, and their colleagues describe the infection of human cells by the intestinal pathogen Salmonella Typhimurium during spaceflight. They show how the microgravity environment of spaceflight changes the molecular profile of human intestinal cells and how these expression patterns are further changed in response to infection. In another first, the researchers were also able to detect molecular changes in the bacterial pathogen while inside the infected host cells.

The results offer fresh insights into the infection process and may lead to novel methods for combatting invasive pathogens during spaceflight and under less exotic conditions here on earth.

Cancer Mortality Among People Living in Areas With Various Levels of Natural Background Radiation

There are many places on the earth, where natural background radiation exposures are elevated significantly above about 2.5 mSv/year. The studies of health effects on populations living in such places are crucially important for understanding the impact of low doses of ionizing radiation. This article critically reviews some recent representative literature that addresses the likelihood of radiation-induced cancer and early childhood death in regions with high natural background radiation. The comparative and Bayesian analysis of the published data shows that the linear no-threshold hypothesis does not likely explain the results of these recent studies, whereas they favor the model of threshold or hormesis. Neither cancers nor early childhood deaths positively correlate with dose rates in regions with elevated natural background radiation.

Keywords: natural radiation, background radiation, HBRA, HNBR, low radiation, cancer, hormesis.