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Introduction to spatial genomics The power of single-cell resolution Mapping the blueprint of health Case study: Bio-Techne Challenges and future prospects References Further reading

Spatial genomics is a cutting-edge field that combines genomics and spatial analysis to investigate the role of genomic features in disease at single-cell resolution.

Spatial genomics is a field of study that focuses on analyzing the spatial organization of genomic features within intact tissues. It involves the simultaneous analysis of various molecular components, including genomic DNA and RNA, through transcriptomic analysis and epigenetic modifications within their spatial context. These techniques aim to reveal the spatial relationships between the different genomic elements and provide insights into the organization and function of single cells within tissues, enabling the molecular connection of a particular genotype to its phenotype.

The Hubble Space Telescope recently suffered a glitch that made it go into safe mode, so it has not been collecting new science data since November 23. But on Friday, December 8, NASA will attempt to get the telescope up and running again by tweaking the operation of one of its three gyros.

The gyros are responsible for keeping the telescope pointed in the right direction, and an error in one of them put the telescope into safe mode to prevent any damage occurring to its hardware. Although it is theoretically possible for the telescope to operate with just one gyro, this would be less efficient and observing time would be lost as it would take longer for the telescope to switch between targets. So ideally, all three gyros can be operational.

The problem with the telescope was first shared on November 29, when NASA announced it was performing tests to understand the issue. Now, the tests are complete and NASA plans to resume operations. “After analyzing the data, the team has determined science operations can resume under three-gyro control,” NASA wrote in a new update. “Based on the performance observed during the tests, the team has decided to operate the gyros in a higher-precision mode during science observations. Hubble’s instruments and the observatory itself remain stable and in good health.”

Max Lugavere is a health and wellness expert, author and a diet advocate. Working out what to eat is hard. Which is odd because everybody does it. You’d think that the science of nutrition, a thing the entire human race relies on multiple times per day, would have some definitive answers. Thankfully Max can explain why it’s such a mess and give some solid principles we can all use. Expect to learn whether carnivore is an optimal diet for us all to follow, whether organic and non-GMO actually makes that much of a difference, what to look for in a magnesium supplement, the actual science of seed oils, whether sunscreen is a danger, why nutrition science is so contested, why calories matter but they aren’t all that matter and much more…

Rosacea is a skin condition that causes reddened skin and rash, usually on the nose and cheeks. There is no test for rosacea, so health care providers will typically diagnose it based on the appearance of the skin and your health history. They may run tests to rule out any other conditions. Learn more from NIAMS:

What is rosacea? It is a long-term disease that causes reddened skin and pimples, usually on the face. It can also make the skin thicker and cause eye problems.

Register for free and learn how to never be afraid of cancer again from health expert: Nathan Crane.

A wave of health concern is sweeping across Europe, echoing similar patterns of pediatric pneumonia seen in China. This concern stems from the increasing prevalence of a rather understated yet potent bacterium – Mycoplasma pneumonia, known for causing “walking pneumonia,” particularly for children.

Mycoplasma pneumoniae is a unique bacterium with the capability of triggering a spectrum of respiratory infections, ranging from mild to severe pneumonia. This pathogen predominantly targets school-aged children, with Public Health France indicating it accounts for 30–50% of community-acquired pneumonia infections in this demographic.

Pneumonia, as it stands, is a condition where the lungs’ air sacs become inflamed, potentially filling with fluid or pus. This results in symptoms that include coughing and difficulty breathing.

Takeaways:

• Barry Young, a public health worker in New Zealand, was arrested for allegedly accessing and leaking personal information from work databases. Young claims the data shows that COVID-19 vaccines are causing deaths.

• Young leaked the data to Steve Kirsch, a vaccine critic, who anonymized the data and uploaded it to his Wasabi file storage account. Kirsch claims the data proves that the COVID-19 vaccines have caused more than 10 million deaths worldwide.

The model expects to generate $203 million in revenue by 2030 from its new health promotion business.

How would you feel if someone offered you a stay at a hotel, but with a catch: they would watch you sleep and collect data from your body? Would you be curious, excited, or creeped out? Well, that’s exactly what a Japanese IT company plans to do as part of its new health promotion business.

NTT’s bold plan

Continue reading “Why a Japan firm plans to track sleep pattern of 10 million hotel guests” »

An international team led by researchers at the University of Toronto has uncovered over 100 genes that are common to primate brains but have undergone evolutionary divergence only in humans—and which could be a source of our unique cognitive ability.

The researchers, led by Associate Professor Jesse Gillis from the Donnelly Center for Cellular and Biomolecular Research and the department of physiology at U of T’s Temerty Faculty of Medicine, found the genes are expressed differently in the brains of humans compared to four of our relatives—chimpanzees, gorillas, macaques and marmosets.

The findings, published in Nature Ecology & Evolution, suggest that reduced selective pressure, or tolerance to loss-of-function mutations, may have allowed the genes to take on higher-level cognitive capacity. The study is part of the Human Cell Atlas, a global initiative to map all human cells to better understand health and disease.