The true nature of reality might be lurking just beyond our senses, according to this theory.

Dense drops of cornstarch and water usually stiffen when they strike a surface, but sometimes they flow fleetingly like a liquid.

Scientists have uncovered a hidden molecular process that helps soils retain water.

APT28 exploits SOHO routers for global DNS hijacking and adversary-in-the-middle attacks, enabling credential theft and espionage.

Docker CVE-2026–34040 enables AuthZ bypass via padded requests, risking host compromise; fixed in version 29.3.1.

Solid tumors show frequent chromosome loss and some compressed cells. Phan et al. show mitotic spindle perturbations cause mis-segregation of chromosomes and heritable chromosome loss. The effects are facets of a “memory” that phenocopies standard nocodazole washout experiments, including cell death and arrest, and that proves insensitive to compression beyond a threshold.

Repairing or degrading damaged lysosomes.

Many key lysosomal repair proteins have an intrinsic propensity to form biomolecular condensates. This points to an emerging paradigm where phase separation, not just individual protein actions, may be a central feature in orchestrating the response to membrane damage.

Recent work has separately highlighted the roles of protein condensates and lipid domains in membrane repair. This raises the intriguing possibility of a mechanistic synergy, where protein and lipid phase separation coregulate each other to mount an integrated response to damage.

A key question is how cells choose between the repair and degradation of a damaged lysosome. The recent discovery of pathways that sense lipid packing defects suggests a new framework, where the biophysical state of the membrane itself helps determine organelle fate. sciencenewshighlights ScienceMission https://sciencemission.com/lysosome-integrity

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Lysosomes are sophisticated signaling hubs whose function depends on membrane integrity. A breach of this barrier, known as lysosomal membrane permeabilization, triggers inflammation and cell death, driving pathologies from lysosomal storage disorders to neurodegeneration. Cells counter membrane damage with diverse repair mechanisms, including endosomal sorting complexes required for transport machinery, sphingomyelin scrambling, annexin-mediated scaffolding, lipid transport, and stress granule plugging. This diversity suggests singular strategies are insufficient, posing an ‘orchestration challenge’ regarding precise initiation, spatial organization, and temporal coordination. This opinion article proposes that biomolecular condensation, initiated by damage cues, acts as a primary organizing principle.

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Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells. They’re scattered throughout the body, including the stomach, intestines, pancreas and lungs. Tumors that arise from these cells are called neuroendocrine tumors and are often rare and slow growing.

Around 70% of all neuroendocrine tumors arise in the pancreas or gastrointestinal tract and are known as gastroenteropancreatic neuroendocrine tumors, or GEP-NETs. Targeting these tumors is often challenging because cells become resistant to treatment.

In a recent study published in the journal Cell Reports Medicine, University of Michigan researchers have identified a new target that can suppress tumor growth. Their findings may lead to new treatment methods for GEP-NETs.