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Location, location, location: Research reveals the hidden power of intracellular neighborhoods

New findings published in Molecular Cell provide details about the hidden organization of the cytoplasm—the soup of liquid, organelles, proteins, and other molecules inside a cell. The research shows it makes a big difference where in that cellular broth, messenger RNA (mRNA) gets translated into proteins.

“You know the old real estate saying, ‘location, location, location.’ It turns out it applies to how proteins get made inside of cells, too,” says Dr. Mayr, a molecular and cell biologist at the Sloan Kettering Institute, a hub for basic and translational research within MSK. “If it’s translated over here, you get twice as much as if it’s translated over there.”

This first-of-its-kind study highlights the degree to which the cytoplasm is “beautifully organized” rather than being just a big jumble of stuff, she says.

Philip Goff: Arguing for Cosmopsychism

Dr Philip Goff (University of Liverpool) speaks at the event “Metaphysics of Mind”, 19th August 2014. Abstract: Cosmopsychism is the conjunction of the following two theses: (i) the cosmos is the one fundamental object, (ii) the cosmos if conscious. I will try out the following argument for this view: Premise 1 – Each and every organic conscious state is irreducible. Premise 2 – No organic conscious state is fundamental. Premise 3 – The only way in which a state can be both irreducible and fundamental is if it is an aspect of a more fundamental state. Conclusion 1 – Therefore each and every organic conscious state is an aspect of a more fundamental state. Premise 4 – If each and every organic conscious state is an aspect of a more fundamental state, then cosmopsychism is highly likely to be true. Conclusion 2 – Therefore, cosmopsychism is highly likely to be true.

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