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Blueberries May Help To Reduce Risk Of Heart Disease

Blueberries are more than just delicious, these little functional foods have been subject to many studies, and now they have been found to have another beneficial ability attributed to their antioxidant rich portfolio, that is the ability to help reduce the risk of heart disease according to a study published in The American Journal of Clinical Nutrition.

This study found that daily consumption one one cup of blueberries over the course of six months resulted in improved arterial function and cholesterol levels in adults with metabolic syndrome. 138 overweight and obese adults aged 50+ with metabolic syndrome were involved in the double blinded and placebo controlled parallel study.

Metabolic syndrome is a term for a cluster of conditions that includes high blood sugar, high triglycerides, and high blood pressure as well as increasing the risk of developing heart disease and Type 2 diabetes.

How to Slow Aging (and even reverse it)

Scientists like Prof Sinclair have evidence of speeding up, slowing, and even reversing aging.
Thanks to LastPass for sponsoring this video. Click here to start using LastPass: https://ve42.co/VeLP

What causes aging? According to Professor David Sinclair, it is a loss of information in our epigenome, the system of proteins like histones and chemical markers like methylation that turn on and off genes. Epigenetics allow different cell types to perform their specific functions — they are what differentiate a brain cell from a skin cell. Our DNA is constantly getting broken, by cosmic rays, UV radiation, free radicals, x-rays and regular cell division etc. When our cells repair that damage, the epigenome is not perfectly reset. And hence over time, noise accumulates in our epigenome. Our cells no longer perform their functions well.

To counter this decline, we can activate the body’s own defenses against aging by stressing the body. Eat less, eat less protein, engage in intense exercise, experience uncomfortable cold. When the body senses existential threats it triggers longevity genes, which attempt to maintain the body to ensure its survival until good times return. This may be the evolutionary legacy of early bacteria, which established these two modes of living (repair and protect vs grow and reproduce). Scientists are uncovering ways to mimic stresses on the body without the discomfort of fasting. Molecules like NMN also trigger sirtuins to monitor and repair the epigenome. This may slow aging.

Reversing aging requires an epigenetic reset, which may be possible using Yamanaka factors. These four factors can revert an adult cell into a pluripotent stem cell. Prof. Sinclair used three of the four factors to reverse aging in the retinal cells of old mice. He found they could see again after the treatment.

Special thanks to:
Professor David Sinclair, check out his book “Lifespan: Why We Age & Why We Don’t Have To“
Assistant Professor David Gold
Noemie Sierra (for polyp images)
Genepool Productions for telomere animations from Immortal: https://ve42.co/immortal
Epigenetics animations (DNA, histones, methylation etc) courtesy of: http://wehi.tv
Animation: Etsuko Uno
Art and Technical Direction: Drew Berry
Sound Design: Francois Tetaz & Emma Bortignon
Scientific Consultation: Marnie Blewitt
Courtesy of Walter and Eliza Hall Institute of Medical Research.

Filming, editing and animation by Jonny Hyman and Derek Muller.

Brent Nally interviews Bill Faloon about his longevity clinical trial

Hayley Harrison is on a constant Roll… Here she sent me privately this video of the great Bill Faloon… I have not completed the video as yet… But the beginning is awesome I will watch late tonight during my down time… Great Respect to Life Extension and Bill Faloon and Neal Francis Vanderee two of the Longevity Movements most interesting characters and the movements many activists such as Hayley “the watchful” Harrison… AEWR.


My mission is to drastically improve your life by helping you break bad habits, build and keep new healthy habits to make you the best version of yourself.

This video is my interview of longevity pioneer Bill Faloon on December 17, 2019.

- Please consider donating: https://paypal.me/BrentNally or my Bitcoin Cash (BCH) address: qr9gcfv92pzwfwa5hj9sqk3ptcnr5jss2g78n7w6f2

SHOW NOTES:

Eating chilies cuts risk of death from heart attack and stroke, study says

For many years, chili has been hailed for its therapeutic properties, and now researchers have found that eating chili peppers regularly can cut the risk of death from heart disease and stroke.

Carried out in Italy, where chili is a common ingredient, the study compared the risk of death among 23,000 people, some of whom ate chili and some of whom didn’t.

Researchers Create Ultimate Non-Stick Coating That Repels Everything – Even Viruses and Bacteria

A self-cleaning surface that repels even the deadliest superbugs: Researchers create the ultimate non-stick coating, with medical settings and food industry in mind.

A team of researchers at McMaster University has developed a self-cleaning surface that can repel all forms of bacteria, preventing the transfer of antibiotic-resistant superbugs and other dangerous bacteria in settings ranging from hospitals to kitchens.

The new plastic surface — a treated form of conventional transparent wrap — can be shrink-wrapped onto door handles, railings, IV stands and other surfaces that can be magnets for bacteria such as MRSA and C. difficile.

Certain Foods Can Cure Infections (In The Lab, That Is…)

A recent Forbes article discussed how minestrone soup could stave off growth of a particular type of malaria. No, this did not mean that we should forget about being excited about a potential new malaria vaccine or no longer take malaria pills when traveling to malaria-ridden regions. Nor did it mean that treating malaria would now become a gourmet endeavor for discerning palates. But the concept was interesting: a science teacher engaged students in an experiment, and found that compared to other soups (yes, soups), minestrone in particular had the strongest ability to prevent growth of the organism causing malaria. In a test tube, that is.

Other foods have also been found to reduce bacteria and stave off illness, but again, this has been in the laboratory, not necessarily in the gut, respiratory tract, urinary tract, or skin. Let’s take garlic. Some like it, some don’t. But using garlic in its pure form or as an extract has become increasingly popular, especially for those exploring alternative medicine options. Its potential uses have ranged far and wide, including treatment of chronic illnesses such as diabetes mellitus and heart disease, as well as infections ranging from bacteria, fungi, and cold viruses. The active antimicrobial component of garlic is allicin, which acts to inhibit enzyme activity necessary for bacterial growth and replication. While studies on garlic’s benefits have been extensive, and many both in and out of the laboratory have been positive, there continues to be need for longer term trials and placebo-controlled studies to assess its actions. The larger studies, to date, have been in the lab. Or perhaps in the kitchen. A study looking at the antibacterial effects of garlic on hamburger meat, specifically limiting growth of the bacteria staphylococcus aureus, demonstrated that adequate amounts of garlic extract added to hamburger meat kept these nasty bugs out for up to two months when refrigerated. If you like garlic-flavored hamburgers, then this is certainly a good way to go. Tasty, and staphylococcus-free!

Curcumin, the active ingredient in turmeric, has also had its day in the limelight when it comes to various medicinal properties. Besides its potential benefit in reducing growth of cancerous tumors, it has also been investigated regarding properties including anti-viral, anti-bacterial, and anti-fungal effects. Many of the results regarding curcumin’s effects have remained in the laboratory, with clinical trials still pending. The most promising work in curcumin’s anti-bacterial effect has been in combating growth of helicobacter pylori, a bacterial pathogen which contributes to gastritis and gastric ulcers. But even in this setting, curcumin was found to be beneficial only when combined with existing medications to treat this disease.

New CRISPR-based system targets amplified antibiotic-resistant genes

Taking advantage of powerful advances in CRISPR gene editing, scientists at the University of California San Diego have set their sights on one of society’s most formidable threats to human health.

A research team led by Andrés Valderrama at UC San Diego School of Medicine and Surashree Kulkarni of the Division of Biological Sciences has developed a new CRISPR-based gene-drive system that dramatically increases the efficiency of inactivating a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.” The new “pro-active” genetic system, or Pro-AG, is detailed in a paper published December 16 in Nature Communications.

Widespread prescriptions of and use in animal food production have led to a rising prevalence of antimicrobial resistance in the environment. Evidence indicates that these environmental sources of antibiotic resistance are transmitted to humans and contribute to the current health crisis associated with the dramatic rise in drug-resistant microbes. Health experts predict that threats from antibiotic resistance could drastically increase in the coming decades, leading to some 10 million drug-resistant disease deaths per year by 2050 if left unchecked.

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