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Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

The ability to proliferate and evolve is one of the defining characteristics of living organisms. However, no artificial materials with these characteristics have been created. In order to develop an artificial molecular system that can multiply and evolve, the information (genes) coded in DNA must be translated into RNA, proteins must be expressed, and the cycle of DNA replication with those proteins must continue over a long period in the system. To date, it has been impossible to create a reaction system in which the genes necessary for DNA replication are expressed while those genes simultaneously carry out their function.

The group succeeded in translating the genes into proteins and replicating the original circular DNA with the translated proteins by using a circular DNA carrying two genes necessary for DNA replication (artificial genomic DNA) and a cell-free transcription-translation system. Furthermore, they also successfully improved the DNA to evolve to a DNA with a 10-fold increase in replication efficiency by continuing this DNA replication cycle for about 60 days.

By adding the genes necessary for transcription and translation to the artificial genomic DNA developed by the group, it could be possible to develop artificial cells that can grow autonomously simply by feeding them low-molecular-weight compounds such as amino acids and nucleotides, in the future. If such artificial cells can be created, we can expect that useful substances currently produced using living organisms (such as substances for drug development and food production) will become more stable and easier to control.

This research has been led by Professor Norikazu Ichihashi, a research director of the project “Development of a self-regenerative artificial genome replication-transcription-translation system” in the research area “Large-scale genome synthesis and cell programming” under the JST’s Strategic Basic Research Programs CREST (Team type). In this research area, JST aims to elucidate basic principles in relation to the structure and function of genomes for the creation of a platform technology for the use of cells.

Freedom of Information Act requests are rarely speedy, but when a group of scientists asked the federal government to share the data it relied upon in licensing Pfizer’s COVID-19 vaccine, the response went beyond typical bureaucratic foot-dragging.

55 years and longer.

That’s how long the Food & Drug Administration in court papers this week proposes it should be given to review and release the trove of vaccine-related documents responsive to the request. If a federal judge in Texas agrees, plaintiffs Public Health and Medical Professionals for Transparency can expect to see the full record in 2076.

A new European satellite will use machine learning to provide rapid, low-cost information on soil conditions to enable smarter agriculture. The project is a model for what novel sensors and artificial intelligence technology can do in a vehicle no bigger than a shoebox.

Edge computing is a fashionable buzz-phrase for the technique of shifting the processing power away from the server farms of the internet and out to where the data is being collected. According to some, edge computing is the next great tech revolution, and in the case of satellites, where communications bandwidth is severely limited, it could be transformational.

The Intuition-1 satellite program will provide soil data to drive European precision agriculture projects, which involve applying fertilizer only when and where needed rather than treating an entire field. Precision agriculture is both more economical and easier on the environment — the catch is that it requires detailed information about soil conditions on a small scale. At present, establishing levels of soil nutrients in sufficient detail involves taking samples from multiple locations and sending them to a laboratory for analysis. This typically takes about three weeks.

*Food Out Of Thin Air. Just Might Work: Revolutionary protein production from renewable electricity and air.*

Solar Foods was chosen as one of the international winners of @NASA ‘s and @csa_asc ‘s @DeepSpaceFood Challenge Nov 15, 2021!

“I chose one whose cutting-edge technology can literally create food out of thin air,” said Martha Stewart, chef and judge. ## ## See also

**Three Minute Science Presentations that change the world. With examples of FAmeLab, ePatch, Solein ** https://youtu.be/6C8vECI77Oo.

This solar farm in Colorado thinks so.

The farming industry is using way too much energy both for its own and the Earth’s sake. To put it in numbers, agriculture uses approximately 21 percent of food production energy, which equals 2.2 quadrillions of kilojoules of energy each year. What’s more, about 60 percent of the energy used in agriculture goes toward gasoline, diesel, electricity, and natural gas.

That’s where agrivoltaics come in. A system where solar panels are in… See more.

Imagine a world in which smart packaging for supermarket-ready meals updates you in real-time to tell you about carbon footprints, gives live warnings on product recalls and instant safety alerts because allergens were detected unexpectedly in the factory.

But how much extra energy would be used powering such a system? And what if an accidental alert meant you were told to throw away your food for no reason?

These are some of the questions asked by team of researchers, including a Lancaster University Lecturer in Design Policy and Futures Thinking, who—by creating objects from a “smart” imaginary new world—are looking at the ethical implications of using artificial intelligence in the food sector.