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US flu control strategy flaws and suggested improvements

In a report to be published in the peer-reviewed journal PLoS Computational Biology and currently available online, Sally Blower, a professor at the Semel Institute for Neuroscience and Human Behavior at UCLA, and Romulus Breban and Raffaele Vardavas, postdoctoral fellows in Blower’s research group, used novel mathematical modeling techniques to predict that current health policy — based on voluntary vaccinations — is not adequate to control severe flu epidemics and pandemics unless vaccination programs offer incentives to individuals.

According to the researchers, the severity of such a health crisis could be reduced if programs were to provide several years of free vaccinations to individuals who pay for only one year. Interestingly, however, some incentive programs could have the opposite effect. Providing free vaccinations for entire families, for example, could actually increase the frequency of severe epidemics. This is because when the head of the household makes a choice — flu shots or no flu shots — on behalf of all the other household members, there is no individual decision-making, and adaptability is decreased.

While other models have determined what proportion of the population would need to be vaccinated in order to prevent a pandemic, none of these models have shown whether this critical coverage can actually be reached. What has been missing, according to Blower, a mathematical and evolutionary biologist, is the human factor.

The human factor involves two biological characteristics, “memory and how adaptable people can be,” Blower said. “These characteristics drive human behavior.”

The model Blower’s team developed is inspired by game theory, used in economics to predict how non-communicating, selfish individuals reach a collective behavior with respect to a common dilemma by adapting to what they think are other people’s decisions. The group modeled each individual’s strategy for making yearly vaccination decisions as an adaptive process of trial and error. They tracked both individual-level decisions and population-level variables — that is, the yearly vaccine coverage level and influenza prevalence, where prevalence is defined as the proportion of the population that is infected. The individual-level model was based on the human biological attributes of memory and adaptability.

The Lifeboat Foundation has the bioshield project

More advice on best actions to survive a nearby nuclear blast

Carnegie Mellon researchers Keith Florig and Baruch Fischhoff offer simple, practical advice: on whether it is worth citizens’ time to stock supplies needed for a home shelter, how urgently should one seek shelter following a nearby nuclear detonation, and how long should survivors remain in a shelter after the radioactive dust settles.


“A number of emergency-management organizations recommend that people stock their homes with a couple dozen categories of emergency supplies,” said Florig of Carnegie Mellon’s engineering and public policy department. “We calculated that it would cost about $240 per year for a typical family to maintain such a stock, including the value of storage space and the time needed to tend to it.”

Their research also suggests that many families who could afford to follow the stocking guidelines might think twice about whether the investment was really worth it, given the low probability that stocked supplies would actually be used in a nuclear emergency.

They advocate simple rules for minimizing risk based on how far people are from the blast. If you are within several miles of the blast, there will be no time to flee and you will have only minutes to seek shelter. If you are 10 miles [downwind] from the blast, you will have 15 to 60 minutes to find shelter, but not enough time to reliably flee the area before the fallout arrives,” said Florig.

However, the prior advice would suggest that if you are 10 miles from the blast that you could move perpendicular to the direction of the fallout plume and get out of the way in under 15 minutes. Needing to move one mile for smaller bombs. So I would think 10–20 miles downwind is a judgement call, but 25 miles you should be able to get out of the way of the fallout plume.

Decisive, immediate action can reduce Pandemic Deaths

Cities that quickly closed schools and discouraged public gatherings had fewer deaths from the great flu pandemic in 1918 than cities that did not, researchers reported on Monday. Experts agree that a pandemic of some virus, most likely influenza, is almost 100 percent certain. What is not certain is when it will strike and which virus it will be.

In Kansas City, no more than 20 people could attend weddings or funerals. New York mandated staggered shifts at factories. In Seattle, the mayor told people to wear face masks.

No single action worked on its own, the researchers found, it was the combination of measures that saved lives. Peak death rates can be 50% to eight times lower. St. Louis authorities introduced “a broad series of measures designed to promote social distancing” as soon as flu showed up. Philadelphia downplayed the 1918 flu.

Philadelphia ended up with a peak death rate of 257 people per 100,000 population per week. St. Louis had just 31 per 100,000 at the peak.

No good vaccine would be available for months, and drugs that treat influenza are in very short supply.

So experts are looking at what they call non-pharmacologic interventions — ways to prevent infection without drugs. They hope this can buy time while companies make and distribute vaccines and drugs.

Because the virus is spread by small droplets passed within about three feet (1 meter) from person to person, keeping people apart is considered a possible strategy.

The U.S. government flu plan calls for similar measures, including allowing employees to stay home for weeks or even months, telecommuting and closing schools and perhaps large office buildings.

The Lifeboat Foundation has a bioshield project

China, Indonesia, India, Japan and the US most vulnerable to asteroids

Using maps of population density, the researchers charted the places likely to suffer the most casualties from asteroids. As might be expected, countries with large coastal populations turned out to be most vulnerable, with China, Indonesia, India, Japan and the US in the top five spots.

The team focused on smaller asteroids because they hit the Earth more frequently. An asteroid a few hundred metres across hits the planet about once every 10,000 years, on average, while those larger than 1 kilometre hit only every 100,000 years or so. Small asteroids are also harder to spot. They considered a range of impact energies corresponding to asteroids between 100 and 500 metres across, striking with typical solar system speeds of about 20,000 kilometres per second.


Simulations show the asteroid impact locations that would produce the most casualties in red. The Pacific coast of Asia is a particularly deadly place for an asteroid to strike because of tsunamis, while a direct strike on some densely populated inland areas could also cause a heavy toll (Illustration: Nick Bailey et al/University of Southampton)

The US faced the worst potential economic losses, since it has a lot of infrastructure on coastlines facing two different oceans. China was second, followed by Sweden, Canada, and Japan.

The Lifeboat asteroid shield project helps to address these risks and Tsunami warning and response systems would also help mitigate loss of life from ocean impacts.

Reducing nuclear bomb casualties

Some information on how to reduce nuclear bomb casualties

If you are downwind of the blast, look at tree tops to see direction of wind and then flee perpendicular to the wind. Because the plumes are significantly longer than they are wide, moving as little as one to five miles perpendicular to the plume can mean the difference between life and death. People in areas upwind of the detonation site, on the other hand, are safest staying where they are.

Today’s hospital burn units provide exemplary but time consuming care to burn victims, who typically arrive sporadically and in small numbers. A nuclear attack would bring a sudden surge of patients, but the medical system could dramatically minimize fatalities by training staff and equipping non-medical people to treat second-degree burn victims in much larger numbers. The focus must be on cleaning the wounds to avoid fatal infections, administering painkillers and then moving on to the next patient. And all of this must occur in the field, since thousands of victims would not make it to a hospital.

The Psychology of Security

An excellent article by Bruce Schneier on the psychology of security is available here. It starts as follows:

Security is both a feeling and a reality. And they’re not the same.

The reality of security is mathematical, based on the probability of different risks and the effectiveness of different countermeasures. We can calculate how secure your home is from burglary, based on such factors as the crime rate in the neighborhood you live in and your door-locking habits. We can calculate how likely it is for you to be murdered, either on the streets by a stranger or in your home by a family member. Or how likely you are to be the victim of identity theft. Given a large enough set of statistics on criminal acts, it’s not even hard; insurance companies do it all the time.

We can also calculate how much more secure a burglar alarm will make your home, or how well a credit freeze will protect you from identity theft. Again, given enough data, it’s easy.

But security is also a feeling, based not on probabilities and mathematical calculations, but on your psychological reactions to both risks and countermeasures. You might feel terribly afraid of terrorism, or you might feel like it’s not something worth worrying about. You might feel safer when you see people taking their shoes off at airport metal detectors, or you might not. You might feel that you’re at high risk of burglary, medium risk of murder, and low risk of identity theft. And your neighbor, in the exact same situation, might feel that he’s at high risk of identity theft, medium risk of burglary, and low risk of murder.

The difference between the feeling of security and true security, and the difference between pursuing one thing or the other, is central to the Lifeboat Foundation’s mission. For example, planetwide risks like synthetic life or unfriendly AI should be analyzed more thoroughly and given more effort than prevention of nuclear proliferation, even if we consider the near-term probability of the former scenarios to be less, simply because their scope is so much larger. For more on this topic, see Cognitive biases affecting judgement of existential risks.

Reducing the Risk of Human Extinction

A valuable paper by Jason Matheny of the University of Maryland is “Reducing the Risk of Human Extinction”. The abstract is as follows:

In this century a number of events could extinguish humanity. The probability of these events may be very low, but the expected value of preventing them could be high, as it represents the value of all future lives. We review the challenges to studying human extinction risks and, by way of example, estimate the cost-effectiveness of preventing extinction-level asteroid impacts.

Continue reading it here.

United States unwilling to spend $300 million for asteroid location

NASA estimates the cost to find at least 90 percent of the 20,000 potentially hazardous asteroids and comets by 2020 would be about $1 billion, according to a report NASA will release later this week. It would cost $300 million if a asteroid locating telescope was piggybacked on another vehicle. The report was previewed Monday at a Planetary Defense Conference in Washington.

The agency is already tracking bigger objects, at least 3,300 feet in diameter, that could wipe out most life on Earth, much like what is theorized to have happened to dinosaurs 65 million years ago. But even that search, which has spotted 769 asteroids and comets — none of which is on course to hit Earth — is behind schedule. It’s supposed to be complete by the end of next year.

A cheaper option would be to simply piggyback on other agencies’ telescopes, a cost of about $300 million, also rejected, Johnson said.

“The decision of the agency is we just can’t do anything about it right now,” he added.

Earth got a scare in 2004, when initial readings suggested an 885-foot asteroid called 99942 Apophis seemed to have a chance of hitting Earth in 2029. But more observations showed that wouldn’t happen. Scientists say there is a 1-in-45,000 chance that it could hit in 2036.

They think it would mostly likely strike the Pacific Ocean, which would cause a tsunami on the U.S. West Coast the size of the devastating 2004 Indian Ocean wave.

John Logsdon, space policy director at George Washington University, said a stepped-up search for such asteroids is needed.

“You can’t deflect them if you can’t find them,” Logsdon said. “And we can’t find things that can cause massive damage.”

Lifeboat has an asteroid shield project

Lasers to detect and deflect asteroids

Graduate student (University of Alabama Huntsville) Blake Anderton wrote his master’s thesis on “Application of Mode-locked lasers to asteroid characterization and mitigation.” Undergraduate Gordon Aiken won a prize at a recent student conference for his poster and presentation “Space positioned LIDAR system for characterization and mitigation of Near Earth Objects.” And members of the group are building a laser system “that is the grandfather of the laser that will push the asteroids,” Fork said.

Anderton’s mode locked lasers could characterize asteroids up to 1 AU away (1.5 × 10 to the 11 meters). Arecibo and other radar observatories can only detect objects up to 0.1 AU away, so in theory a laser would represent a vast improvement over radar.

A one page powerpoint describes their asteroid detection and deflection approach About 12 of the 1AU detection volumes (around the sun in the asteroid belt) would be needed to cover the main areas for near earth asteroids.

40KW femtosecond lasers could deflect an asteroid the size of Apophis (320meters, would hit with 880 megaton force) given one year of illumination and an early start in the trajectory.

Asteroid shields are a project of the Lifeboat Foundation

There are 67 kilowatt solid state lasers and modular laser systems & mirrors for reflecting lasers to achieve more laser power from smaller modules

Asteroid shield related: deflection mission and other proposals

A giant asteroid named Apophis has a one in 45,000 chance of hitting the Earth in 2036. If it did hit the earth it could destroy a city or a region. A slate of new proposals for addressing the asteroid menace was presented today at a recent meeting of the American Association for the Advancement of Science in San Francisco.

One of the Lifeboat Foundation projects is an Asteroid Shield and the issues and points discussed are in direct alignment with Lifeboat. The specific detection and deflection projects are in the Lifeboat Asteroid Shield project.

Edward Lu of NASA has proposed “gravitational tractor” is a spacecraft—up to 20 tons (18 metric tons)—that it could divert an asteroid’s path just by thrusting its engines in a specific direction while in the asteroid’s vicinity.

Scientists also described two massive new survey-telescope projects to detect would-be killer asteroids.

One, dubbed Pan-STARRS, is slated to begin operation later this year. The project will use an array of four 6-foot-wide (1.8-meter-wide) telescopes in Hawaii to scan the skies.

The other program, the Large Synoptic Survey Telescope in Chile, will use a giant 27.5-foot-wide (8.4-meter-wide) telescope to search for killer asteroids. This telescope is scheduled for completion sometime between 2010 and 2015.


David Morrison, an astronomer at NASA’s Ames Research Center, said that “the rate of discoveries is going to ramp up. We’re going to see discoveries being made at 50 to 100 times the current rate.”

“You can expect asteroids like Apophis [to be found] every month.”

Schweickart, the former astronaut, thinks the United Nations needs to draft a treaty detailing standardized international measures that will be carried out in response to any asteroid threat.

His group, the Association of Space Explorers, has started building a team of scientists, risk specialists, and policymakers to draft such a treaty, which will be submitted to the UN for consideration in 2009.

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