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From Mammoth Revival to Human Fertility with Dr. Eriona Hysolli | Singularity University

Join us for an exclusive 1-hour conversation with Dr. Eriona Hysolli, the visionary scientist bridging de-extinction technology and the future of human reproduction. Recognized by Time100 Next for her groundbreaking work reviving the woolly mammoth, Dr. Hysolli brings a unique perspective to reproductive biotechnology that you won’t find anywhere else.

In this informal Q&A session, we’ll explore how cutting-edge technologies originally developed for species conservation are now revolutionizing human fertility treatments. Dr. Hysolli will share insights on:
The latest breakthroughs in synthetic embryos and artificial wombs.
How in vitro gametogenesis could transform infertility treatment.
Lessons from mammoth de-extinction that apply to human reproductive health.
The intersection of genome engineering and fertility solutions.
Near-term commercial applications in reproductive biotechnology.

Drawing from her pioneering work at Yale, George Church’s lab at Harvard, and as Head of Biological Sciences at Colossal Biosciences, Dr. Hysolli offers a rare glimpse into technologies that could redefine human reproduction within the next decade.

The session will feature a moderated discussion followed by audience Q&A. Whether you’re an investor, entrepreneur, healthcare professional, or simply fascinated by the future of fertility, this conversation will provide essential insights into one of biotechnology’s most promising frontiers.

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Groundbreaking project to make artificial human DNA begins

In a groundbreaking development, scientists have started working on the building blocks of human life from scratch.

The project, dubbed the Synthetic Human Genome Project, is being funded by London-based Wellcome Trust, the World’s largest medical charity, with an initial investment of £10 million (approximately $12.7 million).

The research has been largely considered taboo due to fears that it could lead to designer babies or unintended consequences for future generations.

(That’s not my taboo. Creating Synthetic DNA can lead to the creation of synthetic humans. It can be useful in stopping wildlife extinction, but we don’t know the implications of what happens when we do. TheThe BBC also reported on this. Link in comments)


Work has started on a groundbreaking, yet contentious, project to create artificial human DNA from scratch, marking a potential world first.

Star Trek’s Biggest Plot Hole: UFOs and the Prime Directive

In the grand cosmology of Star Trek, the Prime Directive stands as both a legal doctrine and a quasi-religious tenet, the sacred cow of Federation ethics. It is the non-interference policy that governs Starfleet’s engagement with pre-warp civilizations, the bright line between enlightenment and colonial impulse. And yet, if one tilts their head and squints just a little, a glaring inconsistency emerges: UFOs. Our own real-world history teems with sightings, leaked military footage, close encounters of the caffeinated late-night internet variety — yet in the Star Trek universe, these are, at best, unacknowledged background noise. This omission, this gaping lacuna in Trek’s otherwise meticulous world-building, raises a disturbing implication: If the Prime Directive were real, then the galaxy is full of alien civilizations thumbing their ridged noses at it.

To be fair, Star Trek often operates under what scholars of narrative theory might call “selective realism.” It chooses which elements of contemporary history to incorporate and which to quietly ignore, much like the way a Klingon would selectively recount a battle story, omitting any unfortunate pratfalls. When the series does engage with Earth’s past, it prefers a grand mythos — World War III, the Eugenics Wars, Zephram Cochrane’s Phoenix breaking the warp barrier — rather than grappling with the more untidy fringes of historical record. And yet, our own era’s escalating catalog of unidentified aerial phenomena (UAPs, as the rebranding now insists) would seem to demand at least a passing acknowledgment. After all, a civilization governed by the Prime Directive would have had to enforce a strict policy of never being seen, yet our skies have been, apparently, a traffic jam of unidentified blips, metallic tic-tacs, and unexplained glowing orbs.

This contradiction has been largely unspoken in official Trek canon. The closest the franchise has come to addressing the issue is in Star Trek: First Contact (1996), where we see a Vulcan survey ship observing post-war Earth, waiting for Cochrane’s historic flight to justify first contact. But let’s consider the narrative implication here: If Vulcans were watching in 2063, were they also watching in 1963? If Cochrane’s flight was the green light for formal engagement, were the preceding decades a period of silent surveillance, with Romulan warbirds peeking through the ozone layer like celestial Peeping Toms?

Galactic Empire Psychology

We now know that the Galaxy is full of potentially habitable planets. So why do we see no signs that any civilizations have come before us? Matt O’Dowd, astrophysicist and host of PBS Space Time, explains why Fermi’s paradox really is so surprising, and he offers a new piece of evidence that may point towards the solution.

Astrophysicist Matthew O’Dowd spends his time studying the universe, especially really far-away things like Quasars, super-massive black holes and evolving galaxies. He completed his Ph.D. at NASA´s Space Telescope Science Institute, followed by work at the University of Melbourne and Columbia University. Currently he is a professor at the City University of New York´s Lehman College and an Associate at the American Museum of Natural Historys Hayden Planetarium.

Thumbnail © Nadja Niemiec.

This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

Are we heading towards World War III? | Heni Ozi Cukier | TEDxLisboa

This talk dives into four critical dimensions — social, economic, political, and military — to uncover the patterns that led to World War I and II. By comparing those pivotal moments with today’s global dynamics, it reveals troubling signs of growing instability. Are we on the brink of a Third World War? Through the lens of history, this analysis offers a powerful reflection on the present — and a warning to not repeat the mistakes of the past.

Heni Ozi Cukier, widely known as Professor HOC, is an expert in international politics dedicated to making geopolitics more accessible to the general public. He shares his extensive knowledge — and insights into the challenges and dynamics of the contemporary world — through what has become Brazil’s largest geopolitics YouTube channel: PROFESSOR HOC.

He is also behind award-winning documentaries, including Cracol ndia.

In the United States, he worked at the United Nations Security Council, the Organization of American States (OAS), and the Woodrow Wilson Center think tank.

In Brazil, he gained prominence as the founder and coordinator of the postgraduate program in Geopolitics at PUC Paraná, establishing himself as a leading voice in teaching international relations and analyzing global affairs.

He holds a degree in Philosophy and Political Science, and a Master’s in Conflict Resolution and International Peace from the renowned American University in Washington, DC. This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

A Theory Says We Can’t Find Advanced Aliens Because They’re Not Trying to Be Found

For more than 40 years, the Search for Extraterrestrial Intelligence (SETI) organization has turned its gaze toward the cosmos in search for an answer to one of humanity’s greatest questions: Are we alone? Often taking the form of the “Fermi paradox”—a 75-year-old thought experiment that explores why there are so many worlds, yet seemingly no alien civilizations—this grand question has inspired a lot of possible solutions. Maybe life is much rarer than we imagine? Maybe it’s incredibly difficult to evolve into a modern civilization like ours? Or maybe aliens are speaking in a language we simply don’t understand.

Recovery is still possible for critically endangered Hawaiian honeycreeper with urgent intervention

A new study, led by San Diego Zoo Wildlife Alliance, Smithsonian’s National Zoo & Conservation Biology Institute, and additional researchers, offers a unique lens for understanding the unprecedented extinction crisis of native Hawaiian forest birds.

Just 17 out of approximately 60 species of the iconic honeycreeper remain, most of which are facing due to avian malaria. The findings, published in Current Biology, include new evidence that there is still time to save the critically endangered honeycreeper ‘akeke’e—but the window is rapidly closing.

“In a race against time to save the remaining honeycreepers, necessary insights about their survival are found in their ,” said Christopher Kyriazis, Ph.D., lead author and postdoctoral researcher from San Diego Zoo Wildlife Alliance. “Our findings provide a new understanding of the last remaining individuals as recovery efforts forge on in their native forests and in human care.”

The cost of some invasive species could be 16 times higher than we thought

From river-clogging plants to disease-carrying insects, the direct economic cost of invasive species worldwide has averaged about $35 billion a year for decades, researchers said Monday.

Since 1960, damage from non-native plants and animals expanding into new territory has cost society more than $2.2 trillion, more than 16 times higher than previous estimates, they reported in the journal Nature Ecology & Evolution.

The accelerating spread of —from mosquitoes to to tough-to-eradicate plants—blights agriculture, spreads disease and drives the growing pace of species extinction.

Alien Superweapons: The Reality Flattener | 3 Body Problem

This is the weapon that will destroy our solar system in Season 3 of Netflix’s 3 Body Problem: the Dual-Vector Foil. It’s a Dimensional Strike deployed by a super advanced alien civilization called the Singers. Once activated, it expands at light speed, consuming everything in its path. It’s expected to be featured in Season 3 of Netflix’s 3 Body Problem series.

Music:
’The Summoning’ by Scott Buckley — released under CC-BY 4.0. www.scottbuckley.com.au.
@ScottBuckley.
There’s Life Out There — Cooper Cannell.
Jungle — Aakash Gandhi.
Atlantis by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/

Chapters:
00:00 Dimension Strike.
01:55 Dimensional Decay In Sci-Fi.
02:27 Bunker Era.
03:05 Dual-Vector Foil.
04:34 Why Use Dimension Weapons?
06:05 Nature of the Collapsing Universe.

Produced in part with SpaceEngine PRO © Cosmographic Software LLC.

Some 3D models are from NASA: https://nasa3d.arc.nasa.gov/models.

Textures: