Innovative technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.
The technique, known as RIFLE – rotational internal flow layer engineering – enables the construction of separate layers as delicate as one cell thick.
Such versatility is crucial to developing accurate human models of layered tubular tissue for use in research, offering an important alternative to animal models, experts say.
Layered hybrid perovskites show diverse physical properties and exceptional functionality; however, from a materials science viewpoint, the co-existence of lattice order and structural disorder can hinder the understanding of such materials. Lattice dynamics can be affected by dimensional engineering of inorganic frameworks and interactions with molecular moieties in a process that remains unknown.
The research outcomes revealed how the structural dynamics in and out of equilibrium provided unexpected observables to differentiate single-and double-layered perovskites. The study is published in Science Advances.
Michael Levin discusses his 2022 paper “Technological Approach to Mind Everywhere: An Experimentally-Grounded Framework for Understanding Diverse Bodies and Minds” and his 2023 paper with Joshua Bongard, “There’s Plenty of Room Right Here: Biological Systems as Evolved, Overloaded, Multi-scale Machines.” Links to papers flagged 🚩below.
Michael Levin is a scientist at Tufts University; his lab studies anatomical and behavioral decision-making at multiple scales of biological, artificial, and hybrid systems. He works at the intersection of developmental biology, artificial life, bioengineering, synthetic morphology, and cognitive science.
❶ Polycomputing (observer-dependent) 1:59 Outlining the discussion. 3:50 My favorite comment from round 1 interview. 5:00 What is polycomputing? 8:50 An ode to Richard Feynman’s “There’s plenty of room at the bottom“ 11:10 How/when was this discovered? Reductionism, causal power… 14:40 “It’s a view that steps away from prediction.“ 16:20 From abstract: Polycomputing is the ability of the same substrate to simultaneously compute different things *but emphasis on the observer(s)* 17:05 What’s an example of polycomputing? 19:40 They took a different approach and actually did experiments with gene regulatory networks (GRNs) 23:18 Different observers extract different utility from the exact same system. 26:35 Spatial causal emergence graphs (determinism, degeneracy) | Erik Hoel’s micro/macro & effective information. 29:25 Inventiveness of John Conway’s Game of Life.
❷ Technological Approach to Mind Everywhere. 34:20 Tell me 3 things to determine intelligence (ball vs mouse on a hill) 39:50 Jeff Hawkins’ Thousand Brains Theory. 41:05 Agency is not binary, continuum of persuadability. 44:50 Where’s the bottom of agency? Plants & insects far off from 0 46:55 What is the absolute minimum amount of agency? Some degree of goal directed behavior & indeterminacy… 51:05 Life is a system good at scaling. 51:41 “To me, our world doesn’t have 0 agency anywhere.“ 53:50 As an engineer, what can I take advantage of? 55:00 Surely you don’t think the weather has any intelligence to it…
❸ Attractor Landscapes. 58:35 Homeostatic loops, morphological spaces, attractor landscapes. 1:00:35 “Of course we’re living in a simulation!“ 1:06:45 Attractor landscapes, topography, anatomical morphous space (D’Arcy Thompson) 1:12:28 Planaria stochastic, probability of head shape proportional to evolutionary distance between species. 1:15:15 What is the secret of the universe? Attractor landscapes, quantum fields, black holes. 1:19:05 We need a new system of ethics for unconventional minds.
What happens in femtoseconds in nature can now be observed in milliseconds in the lab.
Scientists at the university of sydney.
The University of Sydney is a public research university located in Sydney, New South Wales, Australia. Founded in 1,850, it is the oldest university in Australia and is consistently ranked among the top universities in the world. The University of Sydney has a strong focus on research and offers a wide range of undergraduate and postgraduate programs across a variety of disciplines, including arts, business, engineering, law, medicine, and science.
What about 102,400 MBPS or 100GBPS. This is the speed of data transfer that you can achieve with LiFi Technology. With LiFi you can download 100 movies in just one second. How’s this incredible internet speed possible? It is possible with LED lights. Watch this video till the end for a detailed introduction and truths of LiFi technology.
The bioactivity of most near-infrared II (NIRII) fluorophores are limited, thereby conflicting the achievement of strong fluorescence and high catalytic activities, due to a lack of free electrons in the method.
To overcome this challenge, Huizhen Ma and a research team in translational medicine, neural engineering, physics, and materials at the Tianjin University China developed atomically precise gold clusters with strong near-infrared II fluorescence to show potent enzyme-mimetic activities by using atomic engineering, to form active copper single-atom sites.
These gold-copper clusters (Au21 Cu1) showed higher antioxidant nature with a 90-fold catalase-like and 3-fold higher superoxide dismutase-like activity compared to gold clusters alone. These clusters can be cleared through the kidney to monitor cisplatin-induced renal injury within a 20–120-minute window to visualize the process in 3D via near-infrared light-sheet microscopy.
Researchers from the Center for Regenerative Medicine (CReM), a joint venture between Boston University and Boston Medical Center, have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19.
The two studies describing the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression appear online in Cell Stem Cell.
For more than 20 years, the scientists leading this work have pursued a way to engraft cells into injured lung tissues with the goal of regenerating lung airways or alveoli. They suspected that for engraftment to be long-lived and functional it would be important to reconstitute the stem or progenitor “compartments” of the lung, also sometimes known as stem cell niches.
The SpaceX Crew-7 flight will take an international team of four to the space station. Moghbeli will be the only American abroad, and is leading the mission.
The daughter of Iranian political refugees, Moghbeli went to astronaut camp as a teenager and got a degree at MIT. She played three sports, including basketball, and with space in mind studied aeronautical engineering.
She later had a gutsy career as a Marine attack helicopter pilot, serving in more than 150 combat missions – part family tradition, part service to her country and part in service to her space dreams.
The so-called superconducting (SC) diode effect is an interesting nonreciprocal phenomenon, occurring when a material is SC in one direction and resistive in the other. This effect has been the focus of numerous physics studies, as its observation and reliable control in different materials could enable the future development of new integrated circuits.
Researchers at RIKEN and other institutes in Japan and the United States recently observed the SC diode effect in a newly developed device comprised of two coherently coupled Josephson junctions. Their paper, published in Nature Physics, could guide the engineering of promising technologies based on coupled Josephson junctions.
“We experimentally studied nonlocal Josephson effect, which is a characteristic SC transport in the coherently coupled Josephson junctions (JJs), inspired by a previous theoretical paper published in NanoLetters,” Sadashige Matsuo, one of the researchers who carried out the study, told Phys.org.
Researchers have successfully forced electromagnetic (EM) waves that usually pass right through each other to collide head-on by manipulating time, made possible with the unique properties of metamaterials.
Inspired by the concept of using macro-scale waves like tsunamis or earthquakes to cancel each other out, the manipulation of time interfaces to cause these photons to collide instead of pass through each other could open up a wide range of engineering applications, including advances in telecommunications, optical computing, and even energy harvesting.
Is Using One Wave to Cancel Another Wave Possible?